Post covid itch and hives

I too have the itching on my mid back and have had it since I got the first Covid Vaccine over three years ago. I only got the first two shots (thank the Lord) but the itching is horrible. It comes when I am stressed, get hot, wear something that is irritating to my skin, or sometimes just out of the blue. I don't think I have a rash just a few bumps that I can feel when I reach my hand back. I also get really itchy on my head. I also have switched shampoo's, body wash, laundry soaps, lotions, etc to all things pure. I have been diagnosed with Chronic Spontaneous Urticaria. I have been tested for Mastocytosis (which came out negative) because my tryptase levels are so high and if I get bit by any type of Spyder, bug, mosquito, or Bee I have a severe reaction due to the High Tryptase levels that become even higher. My allergist said that you can have Spontaneous Chronic Urticaria without having a rash, that it can be internal. It is no fun itching all the time. I have been getting injections of Xolair monthly for at least a year and they have helped but this time they injected one shot into my stomach rather than one in each arm and it didn't work at all.

Long COVID has made my skin a wonderland...small intensely itchy rashes/bumps, raised stone like tiny bumps that do not itch, raised red small patches of skin, red areas that form a scale that peels off leaving a scar, etc. I also now have a transient butterfly mask of a rash on my face and two COVID toes that turn anywhere from red to white and send shooting nerve pain up my foot.

Taking Lysine every day is helping with the itchy rashes...some that I have had for months are healing now. Lysine is thought to slow viral replication so doc did a punch biopsy and it is not herpes or shingles...so some other virus is causing all of this.

I started to get that itching on my mid upper back and arms and almost 9 months ago now. I thought it was eczema. I went to one dermatologist and she ened up a freezing a few spots. She said it had to do with my nerves? It was a medically complicated explanation. So I went to another dermatologist for a second opinion (always do that and research it for yourself!).
At the end of the day, it ended up being contact hives, more specifically, see below.
Chronic idiopathic urticaria (CIU) is the persistent, often daily appearance of hives (urticaria) that last for six or more weeks for no known reason. These hives are often itchy welts or bumps that appear when a trigger in the body causes mast cells to release histamine, serotonin, or other chemicals under the skin (which they are finding out is related to long Covid).
I had already been on Dupixent, which both dermatologist said that if I hadn't, that the hives would have been worse. The second dermatologist put me on the Xolair, but before the third injection, I ended up itching worse than before and stopped using it. Right now, I just continue my Dupixent injections (2x a month), use my over the counter FexofenadineHydochloride (allergy relief-two times a day), and my Triamcinolone Acetonide cream (as needed). I traded out my body wash for some Aveeno body wash that is fragrance free and try to keep my skin moisturized. If you have animals, keep your bed sheets clean as often as you can too.
This has at least kept my itching managable. I hope this helps someone out there. I'm actually going to see a third Dermatologist this week, I don't give up that easily to try and figure things out. I've been doing a lot of research on my own and hoping to figure something out. Keep you all posted.

Tell me more about your Dupixent and Xolair issue? You itched more with both? I have been on Xolair for years and it doesn't seem to do much. Just today I convinced my dermatologist to prescribe both. I have heard, albeit anecdotally, that both will do the trick? I use the other meds you mention and none of them do very much. Any further info would be appreciated.

The itching is nuts!
I've had it 4 years with LC. My head, especially my face, arms, hands, feet. It instantly turns into hive and redness.
More and more of the oddest symptoms keep showing up.
Since covid and 4+ years LC I lose so much hair. I do have very long extremely thick hair but, everyday that I brush my hair, I pull large hand fulls out with LC. I'm exhausted with all of this. I've tried dr., after dr.,s without any luck of any help of relief from any of it. The brain fog, dizziness, heart palpitations, breathing issues, sick daily, digestive issues, sleep issues, bloating, swelling and so much more but, the bone and muscle pain OH MY!!!! I can go on and on but in NWI, we've extremely careless dr's that don't care to even remotely attempt to help with ANYTHING JUST HERE TAKE THIS, THIS AND THIS WHEN I SAY TRIED IT, TRIED, TRIED IT and none of it helps with anything period. In this area it's about insurance collections not actual treatment and none of them care to want to help you with LC. I'm exhausted! I feel at this point it's not ever going away and most days are debilitating. I pray for all of you dealing with LC and the destruction and havoc it causes over our bodies and lives.