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Fatigue from Zometa?
I've been on ZYTIGA, Lupron, and Prednisone for 10 months now. PSA is non detectable for the last 7 months. I've had very bad fatigue from all this. I had a tumor at the top of my femur which was radiated and they put a titanium rod in the femur to strengthen the bone. When they put the rod in the femur bone broke. It has been very slow to heal. My oncologist started me on Zometa infusion this week. The Zometa has hit me hard. I can barely get out of bed in the morning. And then two hours later, I have to crawl back in bed. I go through the whole day like this.
Has anyone had similar experience from Zomeda?
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From Mayoclinic
Yes, fatigue is a common side effect of Zometa (zoledronic acid) infusions. Many sources list tiredness or fatigue among the most frequently reported symptoms, often occurring alongside other mild effects such as fever, bone or muscle pain, and flu-like symptoms. This fatigue may develop soon after the infusion and can last for a few days. If fatigue becomes severe or persistent, it is important to inform your healthcare provider
I had an Zometa infusion yesterday (the 4th) Tom and never noticed a fatigue problem.
It may be an interaction with Abiraterone. The two together.
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2 ReactionsI don't reply much to the posts but I've been reading them and often feel short-changed, I get my zometa infusion every three months and don't notice any changes I do have fatigue but never linked it to the zometa, I was told I had PC about four years ago was never offered radeation or surgery, was put on chemo for 5 doses then ADT.
I have stage 4 gleason 9 5+4 ,16 hot spots from shoulders to tail bone, I've seen 3 doctors for radeation but they tell me it won't help me . They don't know but have said at some point I'll get Plavcto, I'm in Utah and I really don't think they care sense I'm 78 and at .01 psa so I'm belly aching on line.
Thanks for all the good words and info on this board I really appreciate it.
Some doctors with zap all of your metastasis two or three at a time. I know people that have had that done, but I’m not sure if it would be effective in your case. Dr. Mark Scholz in Marina del Rey, California believes in SBRT and feels it can resolve peoples problems. You can have a consultation with him, but if not him some center of excellence where they can take a look at what being done and see if they can do more. He was discussing his thoughts at the last PCRI conference At the end of March. You can find it on YouTube and skip to that spot where he starts talking.
Yes, at. 01 it’s hard to do something, The drugs you are taking are working? It would’ve helped to know what drugs you actually on. If you are on both ADT and an ARSI (Zytiga or a lutamide) Then you truly do have to move onto something else If your PSA starts rising.
It is true that even with an undetectable PSA you can have metastasis that are not producing PSA or can’t be detected. There was a study (Wiley) that found some people that are undetectable have metastasis growing.
If you want to target the metastasis, there is radium 223 also known as Xofigo, Which is specifically designed to target Metastasis in the bones.
Then there is Pluvicto and or Chemo.
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