Tymlos causing belly fat?

My impression was that the puffiness of my belly on Tymlos was not fat. But my tummy sticks out permanently from fractures and the Tymlos effect is, in my experience, temporary!

I found this somewhere…and had an appt with a specialist pharmacist in endocrinology (because I was aggravating my endocrinologist with questions he couldn’t answer) and discussed what I had found and he agreed that TYmLoS can do this as it affects the parathyroid. My endocrinologist insisted that it wasn’t in the list of side effects. I call “BS”!
“ Tymlos and fat gain

The literature of experience with parathyroid treatment is replete with abdominal thickening. Enough of that literature had reached scientists that they determined that high levels of calcium in the blood prevents fat cell apoptosis, even in individuals who have never taken drugs that work specifically by increasing serum levels of calcium through the administration of parathyroid hormone. Abdominal fat is also a feature of parathyroid diseases that increase serum calcium.

The statement regarding Tymlos (abaloparatide) and its association with fat gain can be examined through existing literature on parathyroid hormone (PTH) treatments and their effects on body composition, particularly abdominal fat.

Background on Tymlos and PTH

Tymlos is a synthetic analog of parathyroid hormone (PTH) used primarily to treat osteoporosis in postmenopausal women. PTH promotes bone formation but can also have metabolic effects, including influencing fat metabolism.”

So it definitely sounds like TYmLoS is causing f the abdominal fat. I’m now wondering if injecting in the thigh makes a difference? I didn’t even know I could do that. I will
Start taking L-Carnitine as a fat metabolizer and boot it helps. I eat a clean diet and exercise but I am starting to look like a bloated spongebob. I am not happy.

I found this somewhere…and had an appt with a specialist pharmacist in endocrinology (because I was aggravating my endocrinologist with questions he couldn’t answer) and discussed what I had found and he agreed that TYmLoS can do this as it affects the parathyroid. My endocrinologist insisted that it wasn’t in the list of side effects. I call “BS”!
“ Tymlos and fat gain

The literature of experience with parathyroid treatment is replete with abdominal thickening. Enough of that literature had reached scientists that they determined that high levels of calcium in the blood prevents fat cell apoptosis, even in individuals who have never taken drugs that work specifically by increasing serum levels of calcium through the administration of parathyroid hormone. Abdominal fat is also a feature of parathyroid diseases that increase serum calcium.

The statement regarding Tymlos (abaloparatide) and its association with fat gain can be examined through existing literature on parathyroid hormone (PTH) treatments and their effects on body composition, particularly abdominal fat.

Background on Tymlos and PTH

Tymlos is a synthetic analog of parathyroid hormone (PTH) used primarily to treat osteoporosis in postmenopausal women. PTH promotes bone formation but can also have metabolic effects, including influencing fat metabolism.”

So it definitely sounds like TYmLoS is causing f the abdominal fat. I’m now wondering if injecting in the thigh makes a difference? I didn’t even know I could do that. I will
Start taking L-Carnitine as a fat metabolizer and boot it helps. I eat a clean diet and exercise but I am starting to look like a bloated spongebob. I am not happy.

Thanks for this info - very interesting.

The PTH analogs also increase cortisol levels which leads to more belly fat.

I've been on both Tymlos and Forteo in the past year and noticed significant increases in my belly measurement; increases of 1 to 2 inches with no change in diet. In face, I am eating a better diet (more plants, more protein, fewer carbs, no to low sugar) and an increased level of activity.

I'm not sure that injecting in the thigh would make a difference as the analog enters the blood stream and impacts calcium levels systemically.

I found this somewhere…and had an appt with a specialist pharmacist in endocrinology (because I was aggravating my endocrinologist with questions he couldn’t answer) and discussed what I had found and he agreed that TYmLoS can do this as it affects the parathyroid. My endocrinologist insisted that it wasn’t in the list of side effects. I call “BS”!
“ Tymlos and fat gain

The literature of experience with parathyroid treatment is replete with abdominal thickening. Enough of that literature had reached scientists that they determined that high levels of calcium in the blood prevents fat cell apoptosis, even in individuals who have never taken drugs that work specifically by increasing serum levels of calcium through the administration of parathyroid hormone. Abdominal fat is also a feature of parathyroid diseases that increase serum calcium.

The statement regarding Tymlos (abaloparatide) and its association with fat gain can be examined through existing literature on parathyroid hormone (PTH) treatments and their effects on body composition, particularly abdominal fat.

Background on Tymlos and PTH

Tymlos is a synthetic analog of parathyroid hormone (PTH) used primarily to treat osteoporosis in postmenopausal women. PTH promotes bone formation but can also have metabolic effects, including influencing fat metabolism.”

So it definitely sounds like TYmLoS is causing f the abdominal fat. I’m now wondering if injecting in the thigh makes a difference? I didn’t even know I could do that. I will
Start taking L-Carnitine as a fat metabolizer and boot it helps. I eat a clean diet and exercise but I am starting to look like a bloated spongebob. I am not happy.

@oopsiedaisy
I am same! I started off with Tymlos and noticed what I call “my second belly” forming higher on my abdomen. Due to insurance change, I was off all meds for probably a good eight weeks, until I was approved by the new company for generic Forteo. During that time I noticed the second belly diminishing. Now, my dad (who I care for in our home) was hospitalized twice during this time and I was skipping some meals, etc. —so that could have helped as well. But back on meds and that second belly is going strong! (Doesn’t help that I now crave sweets more than I had before—but that could be stress too!)