Colonization of bacteria

Posted by spider109 @spider109, Jan 17 6:16am

I had a sputum culture on 1/6/25. The results showed “Heavy growth- Kleb ssp Pnemonia. I thought it was some type of pneumonia. I went to Mayo Jax for my annual testing, (I have Pulmonary Fibrosis & Bronchiectasis) and the transplant pulmonologist said it is not pneumonia!!! It is colonization of bacteria in your lungs. He did not elaborate on it at all.. prior going to Mayo, my home pulmonologist put me on Amoxicillin/Clavunate, 2x daily for 7 days. I noticed that it was harder to cough up my mucus prior to the culture, and my mucus had been a cloudy light brown color, where as previously had been clear and white. Has anyone had any experience with colonization of bacteria/ Kleb sat Pnemonia. I have no other symptoms besides harder to cough up mucus and discoloration of mucus. Thank-you.

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@tconz

I have Abscessus and I was told by NJH Lab that colonization is like a chocolate chip cookie that has many chips or a few. You definitely want a smaller amount and my NJH doctors told me since my colony count is low ranging 4-12 they don't treat unless I am sick. They said under 50 don't treat and anything above depending on your current condition (coughing, high colony count, etc) they will treat. I hope this helps with the colony count.

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Thank you for that information about the colony count. I was not told that by the lead doctor I saw during my week of testing at NJH. He did say that the count was so low that he didn't want to start antibiotics.
Hearing what you were told at NJH makes me feel better about my decision of not starting the antibiotics that Tyler suggested I start and take. My last colony count is 3. I was in NJH 15 months ago. I feel well, sleep well, appetite good, no uncontrollable coughing, no fever, chills etc. etc. and no shortness of breath.
So yes, your post about NJH's belief about the colony count, it helped me. Thanks.
Barbara

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@spider109

I had a MAC culture done in October with the results in November and it was negative. I know that doesn’t mean that I could’ve got it between now & then though.

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I had bronchoscopy done smear was taken it was negative. The biopsy came back a month later with few MAC cells. How was culture taken ? From sputum? Do pulmonologists treat by culture size differently - heavy vs few? I am currently in waiting mode for 6 months as Dr thinks it will resolve on its own. Wondering if trying to cough daily will help?

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@deborahuhrich

I had bronchoscopy done smear was taken it was negative. The biopsy came back a month later with few MAC cells. How was culture taken ? From sputum? Do pulmonologists treat by culture size differently - heavy vs few? I am currently in waiting mode for 6 months as Dr thinks it will resolve on its own. Wondering if trying to cough daily will help?

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FYI: NJH put me on Nebulizing, Vest, Aerobika and Air Way Clearance and Huff Coughing with having found out I had little to a mild showing of MAC.
If nothing else you might study to learn how to do the different things suggested on the threads here on Mayo Clinic Connect, Air Way Clearance and Postural Drainage, Exercise etc. etc. to help clear the lungs of any possible mucus, if they have said you have BE, Bronchiectasis? What do you think????
Barbara

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@sueinmn

@spider109 Klebsiella ssp pneumoniae is an opportunist!
It invades our weakened lungs if given the chance, and can cause pneumonia. The discolored mucus is a typical sign of this infection.
https://www.webmd.com/a-to-z-guides/klebsiella-pneumoniae-infection
Because it has been around for some time, Kliebsella can also be antibiotic-resistant, so if it returns, your doc may need to have the specimen sensitivity tested to see which drugs will work. If you use oxygen or a CPAP/BiPAP, you may want to take a close look at your disinfecting processes for the equipment, hoses, masks, etc.

Are you feeling better with the antibiotics?

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Hi. I was just diagnosed with Klebsiella pneumoniae in a sputum sample result (had been clear til then in the 2 years since my Bronchiectasis diagnosis). I don't know what it means, really, beyond that it's not good. I would be grateful for info on how it's usually managed, etc. before I speak with my pulmonologist.

Thanks!

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Hi. I just got a culture back today that shows this. Pulmonologist is out of reach for a couple of days and I don't know what standard treatment protocol is.
How are you doing?

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@wsbme74

Hi. I just got a culture back today that shows this. Pulmonologist is out of reach for a couple of days and I don't know what standard treatment protocol is.
How are you doing?

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I’m doing okay, I have noticed mucus is much harder to cough up, and thicker also. I find myself nebulizing more often, sometimes 3x daily but not always. Mucus is always a cloudy yellowish/green color. My Mayo Pulmonologist, and a Mayo Transplant Pulmonologist stated that since I have no other symptoms except the discoloration and harder to cough out tells them that it’s colonized not infection. Any my Mayo Pulmonologist put me on Azrithromycin 250 1x daily I believe to ward off future infections, and put me on a maintenance inhaler called Bevespi to keep airways open 2 puffs 2x daily. Hope this helps.

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@wsbme74

Hi. I was just diagnosed with Klebsiella pneumoniae in a sputum sample result (had been clear til then in the 2 years since my Bronchiectasis diagnosis). I don't know what it means, really, beyond that it's not good. I would be grateful for info on how it's usually managed, etc. before I speak with my pulmonologist.

Thanks!

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The lab will likely do susceptibility testing on your culture to come up with the correct antibiotic. I believe it's highly treatable if recall correctly. Better than growing NTM or fungus, for a little reframing!

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Klebsiella is usually treated with an oral antibiotic for 7-10 days. One of those bugs that's hard to completely eradicate. Good luck to you.

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@spider109

I’m doing okay, I have noticed mucus is much harder to cough up, and thicker also. I find myself nebulizing more often, sometimes 3x daily but not always. Mucus is always a cloudy yellowish/green color. My Mayo Pulmonologist, and a Mayo Transplant Pulmonologist stated that since I have no other symptoms except the discoloration and harder to cough out tells them that it’s colonized not infection. Any my Mayo Pulmonologist put me on Azrithromycin 250 1x daily I believe to ward off future infections, and put me on a maintenance inhaler called Bevespi to keep airways open 2 puffs 2x daily. Hope this helps.

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Thank you. This is really helpful - especially in the absence of any response from my pulmonologist! As always, thank goodness for the patient community!
I had only to nebulize once a day and then do airway clearance at night but this seems to have changed suddenly and the mucus is definitely thicker suddenly and hard to expel. I have asthma, too, so am taking an inhaler to keep my airways more open, too.
Thank you for your help and be well!

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@wolfplanetzero

Klebsiella is usually treated with an oral antibiotic for 7-10 days. One of those bugs that's hard to completely eradicate. Good luck to you.

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Thank you! Yes, I hear it can be tricky, unfortunately. I hate the days that have lapsed not getting a pulmonologist reply, either. Maine is not great with leading healthcare.

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