Brand Name Cymbalta by Eli Lilly is being discontinued!

I have Lungs NETS. Now officially diagnosed,the old carcinoid syndrome flushing, bloating..l have developed bone pain. My Palliative Counselor put me on cymbalta to help me non-stress and help with the pain. I had a menginoma, removed 7 years along and was using seizure medication. a) anyone with Neuroendocrine Cancer should have their SEROTONIN levels checked first. d) oThis form of cancer your serotonin is high, the pills develops more serotonin, in the brain and in your gut. The two places do not mix. Also, sends it out histamines which feeds your tumors and causes extreme itching and flushing.. Only a NET specialist "might" understand all this. For me the brain serotonin skyrocketed causing me to have 3 seizures and felt my eyes were going to pop out of my head. Check, check palliative of do not understand us. It is frustating, l am still walking around with aching where my tumor scare is.

11 year antidepressant survivor and champion of awareness, and 5 year breast cancer survivor here. I'm in the USA. I'm looking for verification from the drug company, or fda, or news media, or pharmacy notice, or other trusted source. That Cymbalta and Prozac name brand (or Duloxetine and Fluoxetine generics) have been recalled by the FDA, and or other authorities, in the US and outside the country. The FDA recalled Cymbalta 3 different times in 2024 for cancer causing ingredients. I am both a rx antidepressant drug survivor, and also a breast cancer survivor. We do NOT need treatments that cause cancer!

The FDA website says the generics are removed from the market, when the name brand drugs are removed, but my research results suggest it may take over a year to remove the generic drugs too.
The FDA also promises the generics and name brand drugs are the same, but my research results suggest that is not necessarily true. White the drug's warning leaflets are identical and the list of ingredients are the same, the generics are too often substandard, and often miss-measured doses. This means risks listed and some not listed increase when taken as directed, and the risks increase if used to measure to taper off the drugs.

It takes approximately 2.5 years to taper off Rx psych drugs, but the drug companies refused to include HOW to taper off. If they did, few people would start the drug. After only 7 days after staring any Rx psych drug, a 5% slow taper method is required to avoid serious and life threatening serotonin syndrome, akathesia, seizures, sexual disfunction, pain, depression, anxiety, head aches, blurred vision, unusual bleeding, birth defects, vomiting, black outs, in ability to speak or write walk talk sleep eat or move as normal, mania, hallucinations, glaucoma, and suicidal thoughts and worse.

Risks are NOT limited to while taking or taping off the drug, and and increase over time, after dose changes, switching psych drugs, does strength, drug food disease interactions, and other certain situations.

Ideally taper off before problems start. Up to 78% of people who tried to stop taking antidepressant drugs ended up reinstating, and increasing risks, and having to start their slow taper all over again. Do not use psych drugs as a bridge or as treatment for the adverse reactions of psych drugs.

The reports are not rare. What is rare are patients and drs who write formal reports to their medical records and the authorities, as the drug's warning leaflets from the drug companies indicate to do if "Any side effects are experienced". Find the leaflets online that are usually hidden by the pharmacies. The online version is the best option. All rx drugs have risks, and the public has a right to know.

The law requires the warnings posted online, so no one can deny or hide them from you. The leaflets should be reviewed with your prescriber before filling the prescription, and independently as well. We should teach HOW to research drugs in school, and the FDA and doctors and pharmacies, so until then, we the PEOPLE are spreading awareness.

More and more doctors are aware, so don't settle for doctors who try to deny the warnings, patient rights, and patient reports of side effects.

I know many people who have not survived psych drugs and the drs who denied the risks and reports.
We demand more information, from the Mayo Clinic. I see you have information on serotonin syndrome, so please help.

My husband's on Duloxetine, and I heard about the recall. I called our pharmacy and asked about the recall. They said the recalls are on specific lot #'s from specific sources, and my husband's was not included.

You are correct. Some generic versions of duloxetine were contaminated and were recalled last October.

Generic duloxetine is not being discontinued. Eli Lilly made the decision to stop production of the name brand drug Cymbalta for "business reasons." They were not ordered to do it, but the patent was expired and they faced competition from generics and resistance by insurance companies to cover the higher cost.

There are a lot better antidepressants than Cymbalta with far less side effects.
I think Zoloft ( Sertraline) is the most described SSRI in that family of drugs and is very well tolerated by the vast majority of people. Combine it with Wellbutrin and give it a try.
Let us know how it goes if you decide to do that.

Sertraline does not have the same beneficial effect on chronic pain, which is what I use it for. This was last on the list of things to try that my body can tolerate and is not an opioid. Thankfully, it has been working for 5 years now without large dosage increases.

I found I get reasonable relief of my musculoskeletal pain (almost my entire spine is a mess except for an area of thoracic below T2. The rest is fused operatively except for areas in my cervical spine above C5 and that shows as fused on my scans etc which the neurosurgeons say is the body’s way to protect itself.
I do have depression and have had chronic pain for over a decade. Other areas have had surgery and those are doing ok. So I stay on duloxetine.