Where do you turn when you've tried many Fibromyalgia medications?

I was prescribed Naltrexone .25 mg, and it's helped so much. I haven't had a full-blown flare up in so long. I can feel when one is coming on, but it never becomes overwhelming where I'm in bed for days at a time. I believe it has lessened the pain but not taken it away completely. I also take 10 mg Baclofen which is a muscle relaxer. Both of these I take at bedtime, they make me sleepy which helps with the sleep issues.

Now, do jump all over me. I’ve had Fibro for 25 years, tried all meds +. I’m not able to take NSAID’s, but I want to have a life. SO? 90% of the time, I take nothing and try and work through it for the day resting as needed. When I WANT to go somewhere ; see grandkids, Bible study, visit a friend or light travel. I take 1/2 Norco. I know it is a major controversy and I understand it, but that is the only way I can enjoy an event. For me, it does nothing but relieve the pain to some degree. I am very disciplined with it and thankful my doctor works with me. 10 per month and never use all of them. Gentle hugs 🤗

I am glad to hear that naltrexone works for you. I was in the original naltrexone study at Stanford and it works just the opposite on me than it did everyone else. I guess you can say I’m one of a kind.😄

I have been prescribed Lyrica, Cymbalta, gabapentin, e-gabalin (I forget the spelling), and a variety of other drugs, none of which worked, some of which made me much sicker (Cymbalta, which my PCP now lists in my chart as an allergen for me). I wish I'd find the targeted medication for fibromyalgia because all these others are broader-scope drugs that can cause quite damaging effects. We call them "side," but they're frontal.

That's exactly what I do! Works like a charm. Just 1/2 Percocet when absolutely needed, no more than 2 halves per day, and not more than 2 or 3 days in a row.
May take 1/2 before babysitting the grand kids this evening!

Yes, took so many and “side effects “ make life worse. Work with your doctor to see if just a pain med works ONLY AS NEEDED. CA will prescribe 10 a month for some. I know OR only want you to take cannabis I’ve been told.

I'm 76 years old and I have experience the same side effects that you are all talking about. I just can't take some of the pills. I had a wonderful doctor allow me to take xanax, and I would take half of a .25 when I really needed it, and it would head off some of the worst pain. At my age, nobody will give me the medication I need for pain and it's very frustrating.

I understand. I tried all the meds they gave me and couldn’t tolerate them (and have a life). One doctor told me HE didn’t want me to have the Norco. I’m afraid I went ballistic on him and among other things asked (so the drug addicts van have it, but I can’t? It was him and not the Insurance he works for. He retired and I went to another doctor who asked who authorized Norco. Turns out the old doctor was the go-to doctor to ok meds. You have to fight for yourself and what is right for you. I’m past your age. I really do Understand the opioid concern, but don’t put me in that box.