Medication following Evenity- Reclast vs Prolia?

If you looked at the graphs, Evenity did work best for the spine (12% improvement) vs ~6 percent elsewhere. 12 % is greater than 6 %.

@normahorn Yes, that is true and I stated that in my comment. What I wanted to illustrate was that while it does improve the spine numbers more than the hip numbers it is still on average quite effective for the hips. More effective than anything else.

The way the statement is made over and over in the different groups it either directly states that it doesn't work well for the hips or more commonly it implies that Evenity does not work well for the hips. The further implication, always without proof, is that there is some other med that would work better.

I'm pretty sure that many people making that type of statement and many reading that type of statement have the impression that Evenity is not very good for the hips and there's probably something better. That's the impression I'm trying to counteract.

@naturegirl5 thanks for your nice comment. I appreciate it.
That's so great that you made such excellent results in the hip area. Despite what I wrote about Evenity helping the hips I personally got terrific gains in the spine and not so much in the TH and FN.
I'm going to add to my weight routine to try to target that area even more. I was already doing squats, deadlifts, and weighted carries. I'm adding lunges and jumping with impact on landing. Very easy on the impact portion though.
Congratulations again on those so important hip gains.

@awfultruth I should add that I did not and do not rely on medication alone. I pay attention to my diet and nutrients to make sure that these are calcium rich. I've been weightlifting for over 30 years, hiking, walking, and x-country skiing. I've always been active and doing things I enjoy. When I started weightlifting I did it because it was something I found I enjoyed. This was long before I knew weightlifting might be helpful for the osteoporosis I had not yet developed. I don't follow any particular program for weightlifting. I have been working with a personal trainer since my total hip replacement surgery 5 years ago. I also workout with aerobics and weights on my own. But now I've added balance training and since this is done in a standing position on one or both legs it is also weight bearing. Like you, I do squats with a barbell, Romanian Dead Lifts with a kettlebell, deadlifts with the barbell (my personal favorite) and weighted carries.

Congratulations to you on your weightlifting and your bone density gains. Let's continue to spread that scientific evidence with references linked and cited right here on Mayo Clinic Connect.

I was on Prolia without any issues for several years until time for my December injection. I had it scheduled and my appointment was canceled. When I called about that, I was told by my doctor’s office that my insurance carrier made the change. After I did my research and spoke with my. Rheumatologist I decided to go with the Reclast. The infusion was no problem and the fact Medicare paid sure made it easier on my budget. However, if you are told you might have some flu-like side effects, I suggest you prepare by hydrating and get some nsaids or Tylenol in your system first. I’ve never had a worse reaction. Wasn’t able to get out of bed the next day. Headache from hell. The good news is I’ll only need one more, most likely!

@dvs01 I have been told that that reaction is unlikely with the second one. It was for me!

I am the opposite of you. I was on Reclast for several years and was informed that after 6 years, I need to get off Reclast and go on another medication. Never had one side effect with Reclast. I am now on Prolia. Had my first shot in October and no side effects. I wax told that I have to stay on Prolia now forever. Were you told that you eventually have to stop your Reclast infusions?

@susanjane77 I am curious whether Prolia, as an anti-resorptive, poses fewer risks than continuing Reclast, also an anti-resorptive. I know people seem to do Prolia for longer, and Reclast is usually 3-5 years.

Were you able to have any drug holidays while on Reclast?

Sorry but i do not understand your question. As i stated, I was on Reclast for several years. I was informed by my physician and the infusion nurses that one can be on Reclast for only a few years and need to stop and go on another medication. My physician thinks that Prolia is the best choice for me but i will never change or go off it. Thankfully, i have had no side effects from Prolia. I hope this continues.

No drug holiday while on Reclast. An infusion once a year.

@susanjane77 I do not know the answer but was asking because anti-resorptive- both Reclast and Prolia- carry risk of jaw necrosis and atypical femur fracture. I just wondered how that risk pans out when you start an anti-resorptive after another anti-resorptive. Maybe someone has a study to contribute on this! They have established that Prolia can be taken 10 years so it may be fine. I would ask my doctor but you sound content with your path.