I have a very high calcium score. What next?

Posted by dpframing @dpframing, Aug 24, 2018

Just joined the site and I'm looking to share with others who have had a high calcium score. I found out today that mine is 2996 and I am scared by this. I am 61 and I am totally asymptomatic. Now I feel like a walking time bomb. I am thinking of requesting an angiogram to see if there's any narrowing anywhere and if it can be corrected with a stent. After a second heart doctor told me that the plaque buildup might be uniform over the course of years with no big problem areas, I am encouraged. But the score still freaks me out, specifically my LAD at 1333. I don't smoke or drink but I have to lose 40 lbs.

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I am a 67 year old with a CAC of 613. Pre-diabetic. BMI of 23. On Rosuvastatin 20 mg, Aspirin 81mg, and Amilodipine 5mgs daily
My LDL 36. Total Choletestrol 117, Triglyceride 64, HDL 67.
My cardiologist is recommending Ozempic 0.25 mg /week by injection for cardiac protection (not for weight loss or diabetes). My out of pocket expense will be $560 a month.
Anyone else got recommendation to start on Ozempic?
Any thoughts? Thank you

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@rtchacko

I am a 67 yr old female with a CAC of 613. On rosuvastatin 20 and Aspirin 81mg. I am a pre-diabetic. My cardiologist is recommending ozempic for cardio-protection. My BMI is 23. My out of pocket expense will be $ 575/month. Does any other cardiologist recommend this?

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I haven’t heard of ozempic for cardio, but wegovy has been approved by the FDA for cardio and, therefore, even Medicare covers it, but you hit the donut hole very quickly and have large out of pocket until the next year. That was fine with me because it made me feel so bad I wouldn’t have continued taking wegovy after two months anyway.

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@llynch17056

I haven’t heard of ozempic for cardio, but wegovy has been approved by the FDA for cardio and, therefore, even Medicare covers it, but you hit the donut hole very quickly and have large out of pocket until the next year. That was fine with me because it made me feel so bad I wouldn’t have continued taking wegovy after two months anyway.

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Thank you. What I understand is both Ozempic and Wegovy are GPL-1 class of medications. I am pre-diabetic and that is why my cardiolgist recommended ozempic. Ozempic helps with insulin resistance as well. From the research I have done from limited evidence out there, GPL-1 group of drugs may give an additional 20% cardiovascular protection, which is significant in my opinion. Yes, I am hearing that the side effects can be difficult to tolerate. I haven't started that yet.
My insurance told me if my cardiologist preauthorizes it, I will have to bay a big co-payment for the first month and afterwards, it will be minimal for a year. I am still trying to decide.

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@rtchacko

Thank you. What I understand is both Ozempic and Wegovy are GPL-1 class of medications. I am pre-diabetic and that is why my cardiolgist recommended ozempic. Ozempic helps with insulin resistance as well. From the research I have done from limited evidence out there, GPL-1 group of drugs may give an additional 20% cardiovascular protection, which is significant in my opinion. Yes, I am hearing that the side effects can be difficult to tolerate. I haven't started that yet.
My insurance told me if my cardiologist preauthorizes it, I will have to bay a big co-payment for the first month and afterwards, it will be minimal for a year. I am still trying to decide.

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I am on Medicare Advantage and my first month was something like $25, my second month was something like $125, then my third month and the months thereafter were closer to $1,000 because I hit the donut hole. Another problem with that is that it can effect my other meds to be higher because of what Medicare paid for those first two months. Anyway, I felt so bad. The reason you lose weight is because you are so nauseated and feel so bad you don’t eat. Not for me. For many reasons.

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Good morning,
I would absolutely demand an angiogram and I'll give you my reason.
I am not overweight, work out 3-4x a week, total cholesterol of 102 (all cholesterol types are, and have been, well in line). EKGs, stress tests, etc always came out perfect. I've been a vegetarian for over 10 years. The model of good health, right? Wrong.
Took a calcium heart scan and my score was 2397!
Long story longer - after an angiogram it was discovered that I had 4 arteries over 90% blocked each. Cardiologist said a fatal heart attack was imminent.
Ended up having quadruple bypass surgery, which saved my life.
Please demand an angiogram.

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@leaddogy2k

Good morning,
I would absolutely demand an angiogram and I'll give you my reason.
I am not overweight, work out 3-4x a week, total cholesterol of 102 (all cholesterol types are, and have been, well in line). EKGs, stress tests, etc always came out perfect. I've been a vegetarian for over 10 years. The model of good health, right? Wrong.
Took a calcium heart scan and my score was 2397!
Long story longer - after an angiogram it was discovered that I had 4 arteries over 90% blocked each. Cardiologist said a fatal heart attack was imminent.
Ended up having quadruple bypass surgery, which saved my life.
Please demand an angiogram.

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So, lead, you had a nuclear stress test - with great ejection fraction? CT was fine, also?

Also, age and statin use would be helpful.

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Yes. Nuclear stress test was fine, CT was fine. I'm 67 and been on statins for 7 or 8 years.

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Interesting - your stats are much like mine!

Been through CT, stress with echo - all OK. Statins for five years. LDL 50, total cholesterol 100, CAC 2350. Just finished nuc stress test - either great LVEF at 78%, or high LVEF at 78%.

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@kisu

In the U.S., one in five people (20%) have the genetic allele, Lp(a). That's around 66.6 million people. There are 3 present drugs to treat Lp(a). There are 2 PCSK9 drugs Repatha and Praluent. Repatha can reduce LDL by 55%-75% and Lp(a) by 26.9%. Praluent can reduce LDL by 43-58% and Lp(a) by 26-30%. The 3rd drug an inclisiran drug, Leqvio reduces LDL by 40-60% and Lp(a) 20-30%. Does Ireland have access to these drugs? Pelacarsen, Ollpasiran, and Zerlasiran can reduce Lp(a) more effectively and may be available in 2-3 years.
Taking a high dose of statin does not decrease Lp(a) and can increase Lp(a) by up to 20%. Since Lp(a) is an independent factor no amount of exercise, diet or statin can reduce it.

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I started taking two 500 mg. doses of slow release niacin daily and my Lp(a) went down dramatically.

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@llynch17056

I am on Medicare Advantage and my first month was something like $25, my second month was something like $125, then my third month and the months thereafter were closer to $1,000 because I hit the donut hole. Another problem with that is that it can effect my other meds to be higher because of what Medicare paid for those first two months. Anyway, I felt so bad. The reason you lose weight is because you are so nauseated and feel so bad you don’t eat. Not for me. For many reasons.

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At least the expense will be limited to $2000 in 2025 thanks to the changes to Medicare. Still a lot, I know.

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