Reclast Infusions: Side-effects & Recovery time

Posted by cindydee @cindydee, Mar 20, 2018

I just had a reclast infusion last week and have had serious side effects. I had the worst flue like aching for 5 days then my lefty arm became full of inflammation in the wrist, elbow and shoulder which caused extreme pain and I lost the ability to straighten my elbow. Ultrasound showed huge amounts of fluid throughout the arm. The right arm is now starting to have the same symptoms. The pain is excruciating. Has anyone else experienced anything like this? Neither the ER doctor nor the Dr. who prescribed the procedure knew what to do to ease the symptoms. Both arms from fingertips to shoulder are swollen and neither elbow will straighten. Anyone else have adverse reactions to the reclast infusion? If yes, how long did it last?

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@basole8

I received my Reclast infusion last Wednesday. I started with the typical flu like symptoms but they have progressed to isolated and severe muscle/connective tissue pain with generalized weakness. I am experiencing terrible muscle soreness and tenderness from typical movements I do daily. I ran errands Friday and by Saturday morning I had terrible pain on my anterior right shin (driving foot). I did light house cleaning yesterday and today I can't grip with my hand due to pain/weakness. I am a physical therapist and I'm nervous to handle my pediatric patients because I can't trust my strength and I'm afraid of the pain that might follow. Has anyone found treatment techniques to address these symptoms. I am hydrating religiously,

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Well when my nurse called back she said to take Claritin. I was shocked. But I did read on the mayo clinic site about taking it. I'll keep you all posted in 2-4 days

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@sillyblone

I have osteoporosis which was diagnosed in 2022. I cannot belive the side effects from the drugs that I am seeing. I am reluctant to even think about it. Please pass on anything that actually works. I would appreciate your comments. Hugs to you all dealing with this !

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I was told Claritin for 2-4 days. We'll see how it works

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@sillyblone

I have osteoporosis which was diagnosed in 2022. I cannot belive the side effects from the drugs that I am seeing. I am reluctant to even think about it. Please pass on anything that actually works. I would appreciate your comments. Hugs to you all dealing with this !

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@sillyblone and others, these side effects are still within the time frame of the "acute phase reaction" that happens mostly with just the first infusion. @linda1974 @basole8 can you let us know if they fade out?

@sillyblone in my experience fractures are worse than any side effects I have encountered, but that's me. Pain and disability from fractures are life-altering.

I have done 5 years hormonal meds for cancer, 2 years Tymlos, 1/2 year Evenity and now 20% Reclast every three months (due to kidneys and afib I have low doses).

I liked Tymlos and got onto it by starting at a low dose and moving up.

Many of my friends, who never come on this forum, do fine on all these drugs. I am sensitive but most aren't.

Of course respect anyone's choices as long as the doctor, and even the forum, have made clear what the different medications do and how they function to increase bone.

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@linda1974

Well when my nurse called back she said to take Claritin. I was shocked. But I did read on the mayo clinic site about taking it. I'll keep you all posted in 2-4 days

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@linda1974, dow did the Claritin work for you? I hope you are getting some relief!! I am a 8 days out and my pain is tolerable with tylonol but still can't resume typical activity. I was afraid to take the claritin on top of everything else but would try if you had success.

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@basole8

@linda1974, dow did the Claritin work for you? I hope you are getting some relief!! I am a 8 days out and my pain is tolerable with tylonol but still can't resume typical activity. I was afraid to take the claritin on top of everything else but would try if you had success.

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The Claritin works fantastic, along with ibuprofen or Tylenol. I felt good yesterday, but today I'm back to normal. Highly recommend it for Reclast

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@windyshores

@sillyblone and others, these side effects are still within the time frame of the "acute phase reaction" that happens mostly with just the first infusion. @linda1974 @basole8 can you let us know if they fade out?

@sillyblone in my experience fractures are worse than any side effects I have encountered, but that's me. Pain and disability from fractures are life-altering.

I have done 5 years hormonal meds for cancer, 2 years Tymlos, 1/2 year Evenity and now 20% Reclast every three months (due to kidneys and afib I have low doses).

I liked Tymlos and got onto it by starting at a low dose and moving up.

Many of my friends, who never come on this forum, do fine on all these drugs. I am sensitive but most aren't.

Of course respect anyone's choices as long as the doctor, and even the forum, have made clear what the different medications do and how they function to increase bone.

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With the help of Claritin, ibuprofen and Tylenol. I'm doing fantastic. I would recommend it

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@linda1974

The Claritin works fantastic, along with ibuprofen or Tylenol. I felt good yesterday, but today I'm back to normal. Highly recommend it for Reclast

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So glad to hear you got through it and are back to normal!

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I just felt achy for a few days; not bad at all. The nurse at the infusion center suggested that administering the drug through the IV for a longer amount of time / slower drip is sometimes helpful in addressing the side effects after. (I'm not sure if this is verified by science.) I drank a few extra glasses of water beforehand. Tylenol helped after also!

I had 2 Reclast infusions over 2 years, then went back to osteopenia. The third year I was on a drug holiday, with a bone density scan scheduled for the end of the year. But then 10 months after my second Reclast infusion I fell and fractured my pelvis and hip (non-displaced fractures; healed on their own in 3 months). Now my endocrinologist wants me to start taking Forteo (self-injecting shots every day for 2 years), followed by another drug.

It's very hard to make these decisions as to what to do, even though my doc has an excellent reputation!

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@theodorastronger

I just felt achy for a few days; not bad at all. The nurse at the infusion center suggested that administering the drug through the IV for a longer amount of time / slower drip is sometimes helpful in addressing the side effects after. (I'm not sure if this is verified by science.) I drank a few extra glasses of water beforehand. Tylenol helped after also!

I had 2 Reclast infusions over 2 years, then went back to osteopenia. The third year I was on a drug holiday, with a bone density scan scheduled for the end of the year. But then 10 months after my second Reclast infusion I fell and fractured my pelvis and hip (non-displaced fractures; healed on their own in 3 months). Now my endocrinologist wants me to start taking Forteo (self-injecting shots every day for 2 years), followed by another drug.

It's very hard to make these decisions as to what to do, even though my doc has an excellent reputation!

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I agree, it seems there are so many different drugs and a lot of times you need another prescription due to a prescription. My prolia caused cholesterol to go up so now on a prescription for that also. Wishing you the best and Happy Holidays!

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Hi everyone, my Reclast infusion was a week and a half ago. On Claritin for 5 days with ibuprofen/Tylenol. I was good. After taking nothing for 2 days I feel like I took 3 steps backwards. My joint pain is back and fatigue. So I'll be getting more Claritin today. Not sure how long I'll have to be on it, but it's better than the pain. I'll be checking with my Dr for sure, but maybe someone here has a suggestion.

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