1. < Kidney & Bladder

Has anyone had their GFR drop 20 points in less than year?

Posted by like2dance2 @like2dance2, Sep 14 10:05am

In January 2024 my GFR went from 53 to 43. It dropped another 11 points between May and August. My Albumin/ Creatine Ratio is 1500. My nephrologist seems totally unconcerned. I am scared. I also have MGUS. Does anyone have these kind of numbers? What did your Doctor say?

Interested in more discussions like this? Go to the Kidney & Bladder Support Group.

cheyne | @cheyne | Oct 28 2:15pm

Hi,
I can tell you when your kidneys stop working you become weak, tired and lathargic within around 12 hours of the event. I managed 18 hours not knowing what was wrong and drove myself to the ED.
My mother in law is 95 and at GFR 18 without any help or medication ever. Frankly I don't understand her Dr's not doing more. She has become an inspiration to me as I have refused any help myself. I do what I can to protect what kidney function that has rebounded, treating it as my first concern. I refuse to let Dr's mitigate my health to treat other health issues I have. I do medicate but not at the expence of my kidney health.
Cheers

REPLY
Lynne Marie | @lbrockme | Oct 28 4:07pm
In reply to @like2dance2 "Thank you all for your comments. My nephrologist has ordered a kidney biopsy. In addition to..." + (show)
@like2dance2

Thank you all for your comments. My nephrologist has ordered a kidney biopsy. In addition to the decline in gfr in 3 months, my creatine albumin ratio has gone fron trace to 1498. At least if MGUS is involved I will know after biopsy, I hope.

Jump to this post

Mine jumps around as well. Hydration, exercise, infection, all play into the changes. Some medications alter it as well. I found that some make it more unstable as well.
Hoping you testing comes back good.

REPLY
robtemery | @robtemery | Nov 5 1:24am

I am looking for answers. I was experiencing excessive urination. Measured 1800 mils overnight. I made an appt with PCP who told me it was diabetes, fasting 140 and 2 hours after meal 149 (different days). I went to an urgent care clinic and the doctor sent me to ER. ER said I had kidney failure GFR 80-90 down to GFR 21 in less than two months. Urologist said I had vesicoureteral reflux. My bladder was not emptying and backing up into kidneys. Utrasound showed bladder was emptying and CT full. The Urologist is proposing a Transurethral resection of the prostate (TURP) and not the preferred Surgery for vesicoureteral reflux that repairs the defect in the valve between the bladder and each affected ureter. A defect in the valve keeps it from closing and preventing urine from flowing backward. (TURP) is the surgical removal of part of the prostate gland. It is one option available to relieve the symptoms of an enlarged prostate or other benign (non-cancerous) prostate disease. I do have BPH but not symptoms such, problems with starting urination, reduced urine flow frequent urination, particularly at night
urgency and possible urgency incontinence (when you lose control of your bladder)
passing drops of urine involuntarily after you think you've finished
blood in the urine.

Common side effects after surgery include bleeding after the operation, retrograde ejaculation, urinary symptoms do not change, erectile dysfunction, urethral strictures and
urinary incontinence. Lastly TURP does nothing defect in the valve between the bladder and each affected ureter. A defect in the valve keeps it from closing and preventing urine from flowing backward into the Kidneys

REPLY
2 replies
celia16 | @celia16 | Nov 6 6:36pm
In reply to @robtemery "I am looking for answers. I was experiencing excessive urination. Measured 1800 mils overnight. I made..." + (show)
@robtemery

I am looking for answers. I was experiencing excessive urination. Measured 1800 mils overnight. I made an appt with PCP who told me it was diabetes, fasting 140 and 2 hours after meal 149 (different days). I went to an urgent care clinic and the doctor sent me to ER. ER said I had kidney failure GFR 80-90 down to GFR 21 in less than two months. Urologist said I had vesicoureteral reflux. My bladder was not emptying and backing up into kidneys. Utrasound showed bladder was emptying and CT full. The Urologist is proposing a Transurethral resection of the prostate (TURP) and not the preferred Surgery for vesicoureteral reflux that repairs the defect in the valve between the bladder and each affected ureter. A defect in the valve keeps it from closing and preventing urine from flowing backward. (TURP) is the surgical removal of part of the prostate gland. It is one option available to relieve the symptoms of an enlarged prostate or other benign (non-cancerous) prostate disease. I do have BPH but not symptoms such, problems with starting urination, reduced urine flow frequent urination, particularly at night
urgency and possible urgency incontinence (when you lose control of your bladder)
passing drops of urine involuntarily after you think you've finished
blood in the urine.

Common side effects after surgery include bleeding after the operation, retrograde ejaculation, urinary symptoms do not change, erectile dysfunction, urethral strictures and
urinary incontinence. Lastly TURP does nothing defect in the valve between the bladder and each affected ureter. A defect in the valve keeps it from closing and preventing urine from flowing backward into the Kidneys

Jump to this post

I hope you get some answers. What are you inclined to do? I wish you all the best. That must have been a terrible shock.

Does anyone know if having a colonoscopy several days before eGFR test can impact the result? I had a two day prep that was not like the first one and it was brutal. I did consume a lot of fluids. I felt my body was out of sorts and dehydrated from all the fluid I lost. The results were normal, but down a little from a year ago. September of last year I was 97. Since then I’ve lost a lot of weight, added exercise, eat a very nutritious diet, and gotten my vitamin deficiency treated. I was not expecting a decline. My doctor said normal, no problem, but…. I’m returning in 3 months to recheck.

REPLY
1 reply
robtemery | @robtemery | Nov 6 8:36pm
In reply to @celia16 "I hope you get some answers. What are you inclined to do? I wish you all..." + (show)
@celia16

I hope you get some answers. What are you inclined to do? I wish you all the best. That must have been a terrible shock.

Does anyone know if having a colonoscopy several days before eGFR test can impact the result? I had a two day prep that was not like the first one and it was brutal. I did consume a lot of fluids. I felt my body was out of sorts and dehydrated from all the fluid I lost. The results were normal, but down a little from a year ago. September of last year I was 97. Since then I’ve lost a lot of weight, added exercise, eat a very nutritious diet, and gotten my vitamin deficiency treated. I was not expecting a decline. My doctor said normal, no problem, but…. I’m returning in 3 months to recheck.

Jump to this post

You are speaking to the wrong individual. One colonoscopy when I turned 50
and now 76. I at one time was a Medical Malpractice Litigator. What I have
heard Doctor testify makes me reluctant to go to the doctor. In a
nutshell, my kids are backed up and no evident stones. Urologist believes
urine is backing up from the bladder because of restriction from BPH. I
have BPH but no symptoms. Wife says bullshit,No surgery. I live in
Waikiki Beach and as I have learned there is only a couple of Urologists
around.

REPLY
Mentor
Ginger, Volunteer Mentor | @gingerw | Nov 7 5:54pm
In reply to @robtemery "I am looking for answers. I was experiencing excessive urination. Measured 1800 mils overnight. I made..." + (show)
@robtemery

I am looking for answers. I was experiencing excessive urination. Measured 1800 mils overnight. I made an appt with PCP who told me it was diabetes, fasting 140 and 2 hours after meal 149 (different days). I went to an urgent care clinic and the doctor sent me to ER. ER said I had kidney failure GFR 80-90 down to GFR 21 in less than two months. Urologist said I had vesicoureteral reflux. My bladder was not emptying and backing up into kidneys. Utrasound showed bladder was emptying and CT full. The Urologist is proposing a Transurethral resection of the prostate (TURP) and not the preferred Surgery for vesicoureteral reflux that repairs the defect in the valve between the bladder and each affected ureter. A defect in the valve keeps it from closing and preventing urine from flowing backward. (TURP) is the surgical removal of part of the prostate gland. It is one option available to relieve the symptoms of an enlarged prostate or other benign (non-cancerous) prostate disease. I do have BPH but not symptoms such, problems with starting urination, reduced urine flow frequent urination, particularly at night
urgency and possible urgency incontinence (when you lose control of your bladder)
passing drops of urine involuntarily after you think you've finished
blood in the urine.

Common side effects after surgery include bleeding after the operation, retrograde ejaculation, urinary symptoms do not change, erectile dysfunction, urethral strictures and
urinary incontinence. Lastly TURP does nothing defect in the valve between the bladder and each affected ureter. A defect in the valve keeps it from closing and preventing urine from flowing backward into the Kidneys

Jump to this post

@robtemery Welcome to Mayo Clinic Connect. Have you been able to get a referral to a nephrologist, to look into why your eGFR took a nosedive? Has it been rechecked recently, at all? In my experience with different maladies, you can have something going on without there being many [or any!] symptoms.

Personally, I would be hesitant to step into any surgery without having confidence in what the doctor is saying, and being sure they diagnosis is accurate.
Ginger

REPLY
View MoreView Less
Please sign in or register to post a reply.