Ofev for Pulmonary Fibrosis??

Have any of you had nosebleeds from taking Ofev?

I used to get nosebleeds from the oxygen (I think it was the oxygen at least). My doctor recommended that I buy nose gel. It moisturizes the nostrils and stopped the bleeding. You can find it next to the other nasal sprays.

Thanks so much! We are currently investigating this possibility. We took note of this when Hubby had one of his extended sneezing fits after dinner tonight -- even without having any of the Esbriet for a couple of days. The sneezing may or may not have been irritation from the POC cannula or the oxygen itself, but at least he didn't have the usual nosebleed afterward. I reminded him to use his Ayr gel. Tomorrow, he's going to try eating dinner without the oxygen cannula. It's complicated. So many variables! I hope he can get this figured out before he speaks with his pulmonologist.
P. S.
He and I just had another little discussion about these details, and came to the conclusion that since he never had nosebleeds before he was taking the pills (sneezing or no sneezing/cannula or no cannula), it must be due to the pills.
Be well!

My 54 year old husband is on Ofev for IPF. We found that his nose bleeds are caused from lack of moisture in his nose. We added humidified air for his oxygen and we put bacitracin in his nose for moisture and helps catch germs. Occasionally he still has nose bleeds.

So you feel the benefits of Ofev outweigh the drawbacks of having nosebleeds? We're not so sure, because my hubby's had a couple of doozies the last couple of days -- even after having stopped the Esbriet 2 weeks ago. Friday night after dinner, and while just sitting in the recliner, his nosebleed was a little more severe than usual, and took about a half hour to resolve, with holding his nose for two 10-minute intervals. Then early Saturday morning when he got out of bed, his nose started bleeding pretty profusely and wouldn't stop for about 45 minutes -- with three 10-minute intervals of holding his nose while I timed it. This is the first time he's had a morning nosebleed. This Sunday evening before dinner, it happened again while just watching football in his recliner. Thankfully, he was able to stop the bleed after only holding his nostrils for 10 minutes. He's using nasal gel and Afrin nasal spray. I'm encouraging him to drink more water and take extra vitamin C -- two suggestions I found online which might help.
He thinks the oxygen cannula may be an irritant (and he's holding it just outside his nose, currently, but it's just the one nostril which is doing the bleeding). I am looking into the possibility of switching to a regular oxygen mask. Any experience with that?

Make sure the doctor agrees with the face mask. A different liter flow will be needed for the oxygen mask. The doctor will tell you what liter flow will be needed. The source of the oxygen will need to be considered also. You will have to consult with the company that supplies the oxygen. So you can see it is not a matter of just switching from nasal cannula to a mask.
Make sure that anything that you use on the nose is water soluble. If petroleum is mentioned in the ingredients of the medicine or topical ointment don't use it with the nasal cannula. It interacts with the oxygen causing the soreness.
I am a retired respiratory therapist so I speak from knowledge and experience.
Hope some of this info will help you out . Have a blessed day.

Update: Hubby saw an Ear, Nose and Throat specialist for these nosebleeds. The ENT treated it by cauterizing a blood vessel. So, it may not have been the Esbriet after all. Doctor suggested that he wait two weeks until nose is healed before re-starting the Esbriet.

Look into the Afrin nasal spray. This may be the cause of some his issues.

Are you saying that Afrin can cause nosebleeds? On the recommendation of some in this group, he was only using Afrin occasionally to help stop the nosebleeds. Not sure if it made any difference, but he hasn't had any nosebleeds since he had the blood vessel cauterized last week.

Hi. Sorry for the slow reply. My understanding from several ENT docs Ive seen over the years is long term use of products like Afrin can cause nose bleeds. It actually drys the out the tissue. I was told to use very sparingly. They prefer I not to use at all. It does work to clear your sinuses but there are side effects. I’ve stopped using it. Little background, I’ve broken my nose twice and then had surgery to “fix”. So I’ve been down this road with Afrin and cauterization. Cauterization can be a limited fix as well. Help this helps. Good luck with it all.