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Nocardia Nova

Posted by mr1123 @mr1123, Oct 18 11:43am

I had MAC and my last sputum tests shows the MAC as negative however Nocardia Nova lung disease, maybe as a result of the MAC.
Just wondering if anyone else has had experience with this.
Currently on antibiotics 24/7 infusion and 2nd antibiotic 4 pills a day.
From what I have read, it can do some bad things to your body and spread to other areas.
If anyone has had this or any info I would appreciate hearing from you.
Prayers for the group.
Miriam

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pacathy | @pacathy | Oct 20 10:05am

I have no first hand info and while I have bronchiectasis, my sputum were negative for MAC. I grew out pseudonymous putida on 1, but elected to watch.

I did a very quick lit search for . Nocardia seems similar to
MAC in that it’s in environment and most often causes respiratory symptoms as you probably already know.

I found a 2018 study from Julie Steinbrink at U of Michigan comparing immunocompromised and nonimmunocompromized patients with various species of Nocardia. There were 112 patients. Two things stood out to me…dissemination (spread) was more likely in patients with solid organ transplants and “All species except Nocardia caviae, Nocardia nova, and Nocardia cyriacigeorgia, which only caused pulmonary infection, were able to cause disseminated infection.” That would seem to be good news for you. A couple things to keep in mind are that the study was smallish and is already 6 years old and patients were even longer ago. Medicine progresses fairly quickly-also good news for you.
I saw a few more recent studies with smaller sample sizes, one from France and 1 Portugal. They emphasized the need to test for antibiotic sensitivity.
Good luck to you and keep us posted.

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mr1123 | @mr1123 | Oct 22 11:27am
In reply to @pacathy "I have no first hand info and while I have bronchiectasis, my sputum were negative for..." + (show)
@pacathy

I have no first hand info and while I have bronchiectasis, my sputum were negative for MAC. I grew out pseudonymous putida on 1, but elected to watch.

I did a very quick lit search for . Nocardia seems similar to
MAC in that it’s in environment and most often causes respiratory symptoms as you probably already know.

I found a 2018 study from Julie Steinbrink at U of Michigan comparing immunocompromised and nonimmunocompromized patients with various species of Nocardia. There were 112 patients. Two things stood out to me…dissemination (spread) was more likely in patients with solid organ transplants and “All species except Nocardia caviae, Nocardia nova, and Nocardia cyriacigeorgia, which only caused pulmonary infection, were able to cause disseminated infection.” That would seem to be good news for you. A couple things to keep in mind are that the study was smallish and is already 6 years old and patients were even longer ago. Medicine progresses fairly quickly-also good news for you.
I saw a few more recent studies with smaller sample sizes, one from France and 1 Portugal. They emphasized the need to test for antibiotic sensitivity.
Good luck to you and keep us posted.

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Thanks for the information. My culture is currently in Texas and doctors are working to see what antibiotics will work on mine.
I appreciate your response.
Prayers for this group.
Miriam

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