Getting off of Seroquel

Posted by anniegk @anniegk, Jun 8, 2018

I have been on 300 mgs. Seroquel ER for over a year for augmenting my antidepressant which is 45 mgs. Of Mirtazapine. I decided to try and get off of the Seroquel. I was on 300mgs ER (extended release). I titrated down to 250 mg ER for 2 months without too many problems.than i titrated down to 200mgs ER just 5 days ago. My plan is to try to titrate off using ER tablets. My thinking is that perhaps the drug will remove its self from my system more gradually. I have had some nausea and a couple of episodes of diarrhea. I also have a very irregular heart beat and was started on 60 mgs of Propranolol ER (extended release) 4 weeks ago. It seems to be helping my heartbeat. I have wondered if the nausea and light headness is from the Propranolol, a Beta Blocker, or the dose reduction of the Seroquel. I also wonder if the way iam titrating the Seroquel is safe. My doctor says it will only take a couple of weeks...I think that is too fast of a taper after being on a drug for over a year. What do you think?

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dlm | @dlm | Mar 26 8:41am

In reply to @brucerwilson "There are only two numbers on blood pressure. Systolic and diastolic. What is the third number?" + (show)

probably heart rate..

jlee1985 | @jlee1985 | Apr 12 9:32pm

Hey i've been on 50 mg of Seroquel for about 4 and a half years I've tried a 2 month taper once and didn't succeed had really bad heart palpitations, really bad insomnia and anxiety I was thinking to do really slow taper about 25% decrease every 3 months. Or maybe slower. Need any advise would really help. Scared to try again!!

kawanhee | @kawanhee | Apr 13 7:50am

In reply to @jlee1985 "Hey i've been on 50 mg of Seroquel for about 4 and a half years I've..." + (show)

I tapered from Ativan .5 very slowly. Suggested by my sleep medicine doctor.
Attached is how I did my taper.
You could do it more slowly. And if I had something going on, I just stayed longer at one “session.”

lava57ca | @lava57ca | May 17 5:24pm

I am trying to give up seroquel xr 50mg. at night time. Doctor has prescribed 25 mg regular seroquel to dose down. Managed to dose down from 100 mg xr to 50 mg xr no problem. Hoping this goes as easy. Having issues with my heart so I need to stop this med. I have been on this for 6 years.
Wish me luck and any advise will be greatly appreciated.

lava57ca | @lava57ca | May 18 10:07am

In reply to @jlee1985 "Hey i've been on 50 mg of Seroquel for about 4 and a half years I've..." + (show)

I am trying the same as you. From 50mg seroquel xr. Doctor suggested 25 mg regular seroquel to help with taper. If you have any other suggestions, please let me know as I know this is the most problematic of all the tapers.
Hoping your taper is going well.

celia16 | @celia16 | Aug 27 6:15pm

What if you are taking only .25 Seroquel?

jennymarie45 | @jennymarie45 | Nov 7 10:27pm

I'm not sure how long I've been on Quetiapine. I take 200mg every night. I also soundlike I'm drunk all the time! I'm slurring my words really badly especially around people I don't talk to on a regular basis. My doctor suggested coming off of it. But didn't help me. I'm seeing him again on Monday Nov. 25th. But I really want to start coming off it now! I was thinking of first cutting myself down to 175mg. Just coming down 25mg a couple weeks at a time.... I know I haven't been on this drug for a year but more than 6 months. My diagnosis is Bipolar type 1 and general anxiety Can anybody help?