Does Camzyos reduce thickening of the heart or manage symptoms?

Posted by haasil @haasil, Jul 16 1:09pm

I have been advised to take Camzyos but can't find any information regarding whether or not this medication actually reduces the thickening of the heart or just for symptoms. Anyone know?

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gjs | @gjs | Jul 19 9:25pm

Thanks for the explanation.

andyherman3 | @andyherman3 | Jul 20 7:58am

The black box warning is regarding the risk of congestive heart failure (CHF). That is why they require repeat echos frequently when you start to be sure your ejection fraction (EF) stays at an acceptable level (usually > 55% but that number may vary). This has to do with how Camzyos relaxes the contraction of the heart. From what I know, that rarely occurs but they are required to warn patient and monitor for it. Drug interactions can worsen this so we need to share what meds we taking and if we change anything. There are newer agents being studied (Aficamtin) which don’t appear to have the same drug interactions and require less echos.