Possible Amiodarone side effects

Posted by heart2024 @heart2024, Jun 24, 2024

I have a long history of heart rhythm problems originally thought to be SVT. I have had adenosen administered 6 times. In addition I am on a pacemaker/defibrillator. I have a stent and a TAVR. I started Amiodarone on May 1, 2024 after being hospitalized with a diagnosis of V-Tach and am now on the maintenance dose. Since May 1, I have noticed a weakness in my left side and in the last 10 days I have noticed that my hands are twitchy to the point of affecting my computer mouse control. Has anyone else had those symptoms? If so, what did you do? This is very disturbing. I am ready to discuss with my doctor stopping the drug.

Interested in more discussions like this? Go to the Heart Rhythm Conditions Support Group.

Hi and welcome to connect. Here is an ongoing discussion about Amiodrone you may find if interest. It's a well used medication and many on. Here are on it so they may be able to replay to your question. I myself did not have those aside affects but every one is different. https://connect.mayoclinic.org/discussion/amiodarone/

REPLY

I was on it only for eight weeks (extended by two weeks due to a little setback with AF, but then got weaned off successfully). It worked over night, but with 800 mg per day for the first week for a loading dose. I didn't want to take it, having researched it months earlier looking for options for my increasingly active AF. But, the ER doctor did consult with my electrophysiologist and they agreed to put me on Amiodarone for a term to get my post-ablation heart to calm down.
To the point, I had no discernible side effects. I knew to avoid sun exposure, and to watch for blue skin and lips, but what I wanted most to avoid were pulmonary hypertension and liver toxicity. When I took my last dose eight weeks later, I was still showing no unwelcome signs. I never was asked to submit a blood sample for them to monitor my system, but maybe in only eight weeks it was not a problem.

The specialist you deal with may feel that what you are experiencing is not unheard of, so at least you can take small comfort in knowing that it can happen, and that Amiodarone is what is causing the new symptoms. However, this may be a new 'nuther development quite unrelated to Amiodarone...so the upshot is you gotta let your experts know what you have going on.

REPLY

I just pulled up the side effects of that drug.!!!!

REPLY
Profile picture for lindy9 @lindy9

I just pulled up the side effects of that drug.!!!!

Jump to this post

So did I and hand tremors and leg weakness is listed. I see my Dr tomorrow.

REPLY

GRAMMAR CORRECTION: *are listed

REPLY

My mom wound up allergic to amiodorone. Her legs and ankles began to swell and she broke out in a rash. For her, it was the iodine that is in the medication.

REPLY

Update: My doctor and I agreed that I should come off the amiodarone immediately. But it will take about 3 months before it is completely out of my system.

REPLY

I was on Amiodarone for about 2 years. Previously on Multaq. I lowered my dose by half and it seemed to work ok, but not 100%. Doc added Coreg and about 5 months I started having symptoms. Fatigue, lightheaded, and muscle tiredness on exercise. I went off both as per Doc advice. The symptoms have been horrible. I am a big hiker/walker everyday…rain, snow, etc. I feel like I can barely walk. My back, leg, and arm muscles feel like lead. Doc has me down for 2 blood tests and a pulmonary function test. I feel like I aged within 5 days! Anyone have these symptoms? I know Amiodarone has a long half life, but I don’t know how long I can deal with this.

REPLY

I assume you have AF
and are using anti arrhythmia drugs to control. Everything I read plus EP advice is to get an Ablation and get off the drugs. Drugs can have serious side effects plus their efficacy deteriorates with time plus drugs only control the arrhythmia they don’t correct the underlying problem of fibrosis

REPLY
Profile picture for chickenfarmer @chickenfarmer

I assume you have AF
and are using anti arrhythmia drugs to control. Everything I read plus EP advice is to get an Ablation and get off the drugs. Drugs can have serious side effects plus their efficacy deteriorates with time plus drugs only control the arrhythmia they don’t correct the underlying problem of fibrosis

Jump to this post

@chickenfarmer The electrophysiology and cardiology communities have said for two years now that ablation is the standard of care for AF. If done skillfully and comprehensively, it can get the person of most drugs and stop any progression toward the undesired outcomes like mitral valve prolapse and enlargement/heart failure.

REPLY
Please sign in or register to post a reply.