New Predictive Blood Test: ctDNA

Posted by colely @colely, Jun 10 8:37am

From http://www.theguardian.com. A new ctDNA blood test identifies returning circulating tumor cells before a scan can find cancer recurrence. The old ctDNA used a technique called whole exome sequencing that typically looks for between 16 and 50 mutations. The new test uses whole genome sequencing and searches for 1,800 mutations making it more sensitive. June 2, 2024. This sounds like a real advancement! I wonder when it will be implemented in our treatment.

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How is this test different from signatera, this test also detects cancer in the blood before it shows up in scans . It also detects CtDna.

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@shireen71

How is this test different from signatera, this test also detects cancer in the blood before it shows up in scans . It also detects CtDna.

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I just looked up the information regarding the Signatera test. I saw two obvious differences. Firstly, they request a tumor sample, besides a blood sample. Secondly, they use the old, whole exhome sequencing which would not be able to find the much larger amount of mutations that the new, whole genome sequencing finds, with the new test.

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@kstar077

I am happy for future test also. I am seeing my oncologist next month and will ask for the new blood test. I am also having my mri July 26. Hope all is well.

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Saw my oncologist two days ago. Asked about new blood test. Said Insurance does not pay for. In the thousands to get it.

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@kstar077

Saw my oncologist two days ago. Asked about new blood test. Said Insurance does not pay for. In the thousands to get it.

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Contact Natera directly to ask. If you have “commercial insurance” (their words, not mine), then they will attempt to bill your insurance; if insurance denies it, they will appeal. If insurance covers it, you would be responsible for cost up to your deductible / cost-sharing / co-pays.

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Insurance does not pay for new blood test. My oncologist said so.

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@kstar077

Saw my oncologist two days ago. Asked about new blood test. Said Insurance does not pay for. In the thousands to get it.

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The Signatera test was estimated to cost US$1,750 to profile five plasma samples.

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@kstar077

Insurance does not pay for new blood test. My oncologist said so.

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The test is available for clinical and research use and is covered by Medicare for patients with colorectal cancer, breast cancer, ovarian cancer and muscle invasive bladder cancer, as well as for immunotherapy monitoring of any solid tumor.

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@elizabet

The test is available for clinical and research use and is covered by Medicare for patients with colorectal cancer, breast cancer, ovarian cancer and muscle invasive bladder cancer, as well as for immunotherapy monitoring of any solid tumor.

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Can this test identify future breast cancer percentages?

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@elizabet

The test is available for clinical and research use and is covered by Medicare for patients with colorectal cancer, breast cancer, ovarian cancer and muscle invasive bladder cancer, as well as for immunotherapy monitoring of any solid tumor.

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What exactly is the blood test called? I am on Medicare and I had breast cancer. I would like to have blood test that picks up on microscopic breast cancer you are speaking of. Thank you

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@kstar077

What exactly is the blood test called? I am on Medicare and I had breast cancer. I would like to have blood test that picks up on microscopic breast cancer you are speaking of. Thank you

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My predictive blood test is called Signatera.

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