Exciting Phase 2 Results from the ARINA-1 Trial!!

Posted by becleartoday @becleartoday, May 1 10:17am

Hi Everyone,

CLINICAL TRIAL UPDATE✨✨
GREAT NEWS ABOUT ARINA-1 nebulizing therapy clinical trial (NOT AN ANTIBIOTIC)!!

Were you in the trial? If so, thank you!!! ✨✨

"These results highlight the important role that ARINA-1 could play in the treatment of non-CF bronchiectasis and are extremely encouraging for patients," said Charles Daley, MD, Professor and Chief, Division of Mycobacterial & Respiratory Infections at National Jewish Health in Denver, Colorado.

"ARINA-1’s novel mechanism improved quality of life and also improved mucus biomarkers in people with bronchiectasis," said Carolyn Durham, PhD, Chief Scientific Officer of Renovion.

"The quality of life data confirms that improving mucus biomarkers, such as viscosity and NE (neutrophil elastase) can reduce symptoms and also improve patient outcomes in this underserved patient population.

These data provide a strong rationale for the continued development of ARINA-1 for NCFBE patients, as well as other populations that suffer from mucus symptoms. We look forward to further analyzing the data and discussing next steps with regulatory authorities."

https://tinyurl.com/yskwez7n

Renovion will discuss study results at the American Thoracic Society Meeting (May 17-22) and present findings at the World Bronchiectasis Conference (July 4-6) in Dundee, Scotland.
Excerpts from BusinessWire April 30th

Warm regards,
Linda Esposito

PS- What's better than sharing good news?

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

scoop | @scoop | May 4 5:22pm

In reply to @becleartoday "It will be a couple of years. They still have to do a phase 3, and..." + (show)

Sorry I was not clear -- how soon until phase 3 the next round of clinical trials if you happen to know. Thanks @becleartoday for posting about this!

becleartoday | @becleartoday | May 4 5:42pm

Nothing is currently planned. I believe they’re waiting for funding.

spider109 | @spider109 | May 5 4:48am

I would be VERY INTERESTED in participating in the clinical trial. I’ve been diagnosed for 3 yrs with NSIP with fibrosis & Bronchiectasis, which has been said to be “significant” according to Mayo Jax Pulmonologist Dr.Lee. I live in upstate NY but would gladly travel to other northeastern hospitals to participate. I also go to Florida in the Winter and could participate there also. Please Linda, post sites if you are allowed to for these trials. Thank you

becleartoday | @becleartoday | May 5 5:44am

I understand your interest because I feel the same way. Right now a phase 3 is not scheduled. Often these trials are very expensive and they need to gather up financial backing. When they are ready to move ahead, I will submit the trial to the Mayo IRB so that I can post it.

Enjoy the day,
Linda Esposito

laureltn | @laureltn | May 5 8:56am

In reply to @becleartoday "Will do! Are you in the Tennessee support group? NTM info and research has over 40..." + (show)

Good morning! If I can help with the Tennessee support group, please let me know! I'm in Knoxville today, but will be back home later today and will be happy to give you more information!

Laurel

helenmp | @helenmp | May 5 3:18pm

In reply to @becleartoday "Will do! Are you in the Tennessee support group? NTM info and research has over 40..." + (show)

How do you find a support group in your state?
I live in Florida.
Any information would be great. There seems to be many resources through group participation, but I have never been given much information besides I have MAC.
Example…. I never heard about drinking specific water except in this site.
Currently, I have occasional coughing, mostly in the morning, but what symptoms do I need to be aware of if/when this progresses.
I have several questions but don’t seem to have many answers. I am a very proactive person with my medical care in general, but right now, I feel like I am in limbo, waiting for something, but not sure what? Not a comfortable place for me at all.
I hope you can offer some ideas.
Thanks
Helen

becleartoday | @becleartoday | May 5 3:57pm

In reply to @helenmp "How do you find a support group in your state? I live in Florida. Any information..." + (show)

Hi Helen,
We can help you! I am a volunteer patient ambassador for the nonprofit Bronchiectasis & NTM Info and Research. We have over 35 support groups with several in Florida. Please email me at PatientAmbassador1@ntminfo.org and we will find you the right group.

Best,
Linda Esposito

scoop | @scoop | May 5 4:30pm

In reply to @becleartoday "Hi Helen, We can help you! I am a volunteer patient ambassador for the nonprofit Bronchiectasis..." + (show)

Curious if the nonprofit Bronchiectasis & NTM Info and Research is a patient registry? In other words, to join the site do they require you to register as a patient for access to medical records for search purposes?

becleartoday | @becleartoday | May 5 4:46pm

In reply to @scoop "Curious if the nonprofit Bronchiectasis & NTM Info and Research is a patient registry? In other..." + (show)

No. It is a nonprofit. NTM info.org. Many institutions including the COPD Foundation and UT Tyler reference these support groups. Some groups meet in person and others are virtual. I learned a lot in my NYC group. Linda