Evenity and side effects: What helps joint and muscle pain?

I am confused @jillgirl. Evenity is two injections, one right after the other. You used the word "infusion." Are you referring to Reclast? There is no way to have a slow injection. Can you clarify?

It sure sounds like you should not do any more Evenity!

I am referring to Evenity. You are correct, it is two injections. My mistake to call these injections infusions. But it isn't like any injection/shot I have taken. The first visit one nurse place the needles in the back of each arm, both given at the same time and finishing in 20 minutes. I was told I had to stay for observation for 30 minutes. With the second injection one person on each side placed the needles in the back of both arms at the exact same time, counting 1, 2, 3 -needles in. It was over in a minute or two. I was told I did need to stay afterwards and was free to leave. I believe the injections were given too fast due to the dizziness and immediate facial problems. It would be interesting to know how others have been given their Evenity injections.

Hi, I got my first set of shots a month ago and felt the same way. I kept passing out for a few minutes and then waking up and then passing out again. I was so tired for the rest of the day I couldn’t even make dinner that night. In the couple of weeks after that first treatment I would get bad bouts of exhaustion but I’ve been having those on and off anyway so I’m not sure what’s the Evenity and what’s something else going on with me. I get my second set of shots tomorrow. I’m 53 with very severe OP (4.1 spine, 3.5 hips). The other symptom I’m wondering if anyone is experiencing is aching joints. My back and knees hurt even before Evenity but now my hips hurt too and my knees hurt more. My back already hurt a lot so that’s about the same. I hope that’s helpful. I’m grateful to everyone who shares on here because this is kind of a scary experience and it’s so helpful to hear what others have experienced. I’ve always been in good health so this has been a bit of a shock. Wishing everyone well!

I had the two shots given by one nurse, separated by 3 minutes (at my request and my allergist's), but the injections themselves cannot be slowed down. Maybe you are thinking of slow infusions for Reclast?

I had similar reactions to yours but they improved when I had them in my thighs.

My kid has type 1 diabetes so I knew that thigh injections are absorbed more slowly. If you react this way, I would avoid tummy for sure- the site of fastest absorption, for insulin anyway. And insulin is also subcutaneous in fat.

This kind of immediate "reaction" is not a "side effect." Side effects tend to be most intense around day 12 in my experience. I saw an allergist after my first injections . I hope you will see an allergist before going near Evenity again, if you ever do!

@songbird18 Keith McCormick, the author of "Great Bones," told me that 40% of his patients on Evenity have joint pain. I am talking with him next week and will ask a follow-up question on how long this lasts after treatment, if it does.

Yes, I have my most-intense joint pain around day 10 after injection.
I have had 4 so far, and no change in that.
My pain is in my left shoulder and hip--not sure if it is in joint or in muscle--had severe injury to both from fa bad fall 15 years ago, which may or may not be related to current Evenity injections.
But fatigue seems to be lessening over the course of the shots.
#5 this week..
Good luck to you, Songbird, and to us all.

You have to go that far to get your injections? You're a trooper.
I walked soon after my first two, and the day that I had the third, the weather was crummy, so I just did some light exercise at home. That could be the reason.

Jollyroger
I’m so glad I just registered and you’ll (yes I’m from the south!) are teaching me so much!!
I had my 12th Prolia injection March 27, 2024.
I was concerned to keep getting Prolia after a friend told me her doctor stopped her from taking Prolia but not why.
I had asked my primary care doctor to order Evenity because my Bone Density had not improved? but he didn’t so I went ahead and got the injection. My Sister told me yesterday that our cousin had posted on FB about Prolia Trap!
I Google and found ALL the problems!
The FDA warning issued in Jan. Etc.
So I signed up for Mayo - because I can trust them!
So thanks for teaching me so much today.
My first action is to find an endocrinologist!
Thanks again!

Thanks for your reply and information on best location for the injections.
I will request thigh injections, not the back of the arms. And certainly not a 1-3 minute injection.
I did have yet another face burnig/itching/extreme red blotchiness about a 1.5 weeks later. My face was burning so badly I placed an icepack on it.
With most of my Sjogren's flares, my face has these reactions, yet milder. I think the Evenity is causing the Sjorgen's flares, when involving my face, to triple. I had to resort to 5% lidocaine cream to deaden my face.

That is the timing of my burning sensations as well. @jillgirl
So it is not immediate so not allergic-?

Perhaps those of us with autoimmune issues are more prone to these problems.