Repatha as a treatment for high HDL Cholesterol

Posted by sue225 @sue225, May 7, 2019

Think I have posted this before but no feedback as of yet. Very interested in hearing from people who are on Repatha (evoculomab) to treat their high LDL levels. I am one of those patients.

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Profile picture for agb @agb

I had an appointment with my cardiologist this week and asked whether it’s true that lowering the LDL below 70 would start to reverse arterial blockage and if so, how. Here’s what he said:

Yes, absolutely. When you have a cut, your body immediately goes into healing mode and in just a few days, the cut is usually well healed. If every day you beat on that cut, your body would be spending its effort to fix what you damaged by beating the wound and not the wound itself.

In a similar way, when you lower LDL, your body will stop fighting it and will start to smooth and harden the plaque in your arteries. This lowers the risk of a piece of soft plaque breaking off, causing a heart attack, stroke, or other event and overall, lowers the risk of a cardiac event. Over a very long time, at glacial speeds, the hardened plaque will actually get smaller, but he noted one might have to live to 150 to see the difference.

Lipitor has lowered my LDL from 252 to 109 and Repatha lowered that again to 27. Fingers crossed here

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Wow. Thanks for your thoughtful reply. When the Repatha lowered it further, were you still on the Statin, too? I have to say that for the first time I am excited to see my numbers on my next blood work. I have a real love/hate relationship with medication. I think a lot of it is unnecessary if you are willing to do the work of living a healthy lifestyle. Obviously, not always the case.

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Profile picture for HomeAgainLA @llynch17056

Wow. Thanks for your thoughtful reply. When the Repatha lowered it further, were you still on the Statin, too? I have to say that for the first time I am excited to see my numbers on my next blood work. I have a real love/hate relationship with medication. I think a lot of it is unnecessary if you are willing to do the work of living a healthy lifestyle. Obviously, not always the case.

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yes, still on 80 mg atorvastatin, 10 mg Zetia, plus the Repatha

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Profile picture for agb @agb

yes, still on 80 mg atorvastatin, 10 mg Zetia, plus the Repatha

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Wow

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So, to summarize what you have said re your cardiologist's statement - you might have a lower CAC score if you double your lifetime?

I have not yet heard of anyone lowering their calcium score (CAC score) ...

Anyone?

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Profile picture for mayoconnectuser1 @mayoconnectuser1

So, to summarize what you have said re your cardiologist's statement - you might have a lower CAC score if you double your lifetime?

I have not yet heard of anyone lowering their calcium score (CAC score) ...

Anyone?

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That's my understanding, yes. He also told me that he expects my CAC score to increase, as plaque hardens and there is less soft material around. I don't expect to be around long enough to see a decreased score.

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Has anyone used a probiotic to help with the loose stools cause by taking Repatha? And, most important, has it helped? thanks. d

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Profile picture for cepheid815 @cepheid815

My cholesterol is ideal since i quit statins and added cinnamon to my diet. My regular doctor does not believe it. But it was a suggestion of another doctor. My arteries were all clear for my open heart surgery. My surgery was needed for removal of a benign tumor which was a once in 10years event for him personally. My experience supports the cinnamon recommendation. At my request during surgery the maze was performed which limited my AF from a frequent to a seldom visitor. The maze procedure was easier to perform because the arteries did not require any time. I swear that my spouse and i have managed to eliminate use of statins with cinnamon.

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@cepheid815 I too would like to know what type of cinnamon, how often, and where do you get it. Cinnamon sometimes can be hard on stomach acid, I think.

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Profile picture for Lou @lcd

Be sure to let the Repatha "warm up" a bit before injecting. I have found that upper leg is much better than pinching belly area. I was getting bruising and marks that lasted months in belly area. I have had limited success, and will be talking to my doctor soon to stop the medication. Ezetimibe has been a miracle drug for me with overnight success after years of fighting hereditary cholesterol.

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@lcd Wow, interesting! I have no fat in my thighs so I can't squeeze enough flesh to be able to get the injector to plunge into my upper thighs. The belly area is best and the backs of my arms, with help from my husband. I also take Ezetimibe and the combination has been great.

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