Anyone Taking Mirtazapine for Sleep?

Posted by dfb @dfb, Jan 24 12:26pm

I've recently titrated off of 450mg of Venlafaxine that I had been on for fifteen years. While I was on it I would wake up every two hours until they put me on 150mg of Seroquel, but that makes me depressed and groggy, so I no longer take that.

Even though I am no longer on Venlafaxine I still wake up every two hours. I believe, and I think my provider now agrees, that the sleep disturbances are at least contributing to my depression and anxiety, if not the cause.

Soooo, my primary care provider has ordered a sleep study that I don't suspect will find anything. And my psych provider has just prescribed Mirtazapine. I of course have looked it up but I'm interested in any first hand experiences with the drug.

Does it help you sleep through the night?
Where you able to stop taking it?
How bad where the side effects?

Thank you for any information you can provide.

May you live in peace and good health.

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My background is treatment resistant depression and generalized anxiety disorder, with a past history of panic disorder.
I have been taking 15 mg of mirtazipine at bedtime for approx 2 months. I don’t notice any side effects, and I do sleep through the night. I should mention I also take 1 mg clonazepam at bedtime.
Before I started this regimen I didn’t ever sleep all night, and awoke with severe anxiety. I haven’t tried getting off it, so I have no input for that.
I hope you have success with it.

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@charlie11

My background is treatment resistant depression and generalized anxiety disorder, with a past history of panic disorder.
I have been taking 15 mg of mirtazipine at bedtime for approx 2 months. I don’t notice any side effects, and I do sleep through the night. I should mention I also take 1 mg clonazepam at bedtime.
Before I started this regimen I didn’t ever sleep all night, and awoke with severe anxiety. I haven’t tried getting off it, so I have no input for that.
I hope you have success with it.

Jump to this post

Thank you!

Has your appetite increased? I understand weight gain can be an issue.

Increased body fat exacerbates depression and I don’t need that.

Thank you again.

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I started taking Mirtazapine 15 mg approx. 8 months ago due to severe insomnia for 2 months. This is the only medication that worked for me, along with 1/2 a pill of zoplicon ( 7.5 mg). I take both just before bed and get at least 8 hours of sleep. I do wake up 1-2 per night but go right back to sleep. The zoplicon alone stopped working for me, but the two are giving me a good nights rest. No side effects other than increased appetite. Keep healthy snack foods around ( fruit, nuts, cheese) and so far my weight has not changed.

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My psychiatrist added Mirtazapine to my Wellbutrin when it started to help less with depression. I tried Abilify first and found it had no effect, but Mirtazapine got me back to a more stable place. I don't recall any side effects, but I know I'm complicated. I also took Clonazepam for 15 years until 3 months ago, and it helped my quality of sleep, along with a CPAP machine. If you snore or wake up suddenly, a sleep study might be helpful in deciding what treatment would be best for you. Obesity is a common factor, but I've always been thin - my wife uses the word skinny - so weight isn't necessarily a determining factor. However, uncontrolled sleep apnea can result in a number of serious health issues, so it's not a bad idea to rule it out.

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@jimhd

My psychiatrist added Mirtazapine to my Wellbutrin when it started to help less with depression. I tried Abilify first and found it had no effect, but Mirtazapine got me back to a more stable place. I don't recall any side effects, but I know I'm complicated. I also took Clonazepam for 15 years until 3 months ago, and it helped my quality of sleep, along with a CPAP machine. If you snore or wake up suddenly, a sleep study might be helpful in deciding what treatment would be best for you. Obesity is a common factor, but I've always been thin - my wife uses the word skinny - so weight isn't necessarily a determining factor. However, uncontrolled sleep apnea can result in a number of serious health issues, so it's not a bad idea to rule it out.

Jump to this post

What dose are you on and have you experienced weight gain?

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@crbarefoot

What dose are you on and have you experienced weight gain?

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I take 45mg of Mirtazapine, and I don't think I experienced weight gain associated with it. I'll look back at my records and see if it did.

Jim

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@crbarefoot

What dose are you on and have you experienced weight gain?

Jump to this post

I think I had slowly gained weight during the years around that time, so in 2017 I cut back on sweet snacks and on second helpings at meal time, and got down from 208 to my comfortable weight of 155. I work to maintain around 160 lbs, which is about right for my 6'2" height. So, it's possible that I gained weight over the first few years of starting it, but it was quite gradual.

Jim

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Thanks. I just did not know if lower doses caused less hunger. I was always beyond starving on 30 mg
Ty!

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I've just started taking 15mg at night for sleep about a week ago. So far I have not experienced any improvement in my sleep patterns. I am, however hungry all the time.

I've recently lost thirty five pounds and need to lose another twenty five to reach a healthy weight. I can not afford to gain weight as I believe the excess weight is a significant contributor to my depression.

I am so tired of side effects from medication and the providers who dismiss them.

I do not believe I can achieve good mental health if my physical health is a mess. The body and the mind are one integrated system.

Yeah, I'm frustrated.

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