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Comments (1,094)

This is awesome! Thank you so much! Can I ask what the duloxetine does for you?...

https://connect.mayoclinic.org/comment/1338257/

Can I ask what the duloxetine does for

Discussion: Low Dose Naltrexone and Neuropathy

Support Group: Neuropathy

Posted: Jun 30, 2025

I've been taking duloxetine to treat my depression for almost 10 years, along with nortriptyline.

https://connect.mayoclinic.org/comment/1307981/

I've been taking duloxetine to treat

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: May 19, 2025

I've been on Duloxetine for 2 years with no problems. I take it at night before...

https://connect.mayoclinic.org/comment/1269151/

I've been on Duloxetine for 2 years

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: Mar 29, 2025

Had side effects of diarehea nausea etc. Duloxetine does not have the side effects for me.

https://connect.mayoclinic.org/comment/1377410/

Duloxetine does not have the side effects

Discussion: Anyone taking Mirtazapine? Is it working for you? Any side effects?

Support Group: Depression & Anxiety

Posted: Aug 23, 2025

I stopped Duloxetine after only two days of 20mg. Side effects were terrible.

https://connect.mayoclinic.org/comment/1389812/

I stopped Duloxetine after only two

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: Sep 8, 2025

Hi, @boo55 - how are things going with the sleeplessness you were experiencing from the duloxetine...

https://connect.mayoclinic.org/comment/261793/

sleeplessness you were experiencing from the duloxetine

Discussion: I can't sleep when taking Cymbalta: What else can I do for pain?

Support Group: Chronic Pain

Posted: Jun 10, 2019

Hi, @chowmama2 - I'm glad that taking duloxetine has been a good choice for you. I'm...

https://connect.mayoclinic.org/comment/92462/

chowmama2 - I'm glad that taking duloxetine ... mentioned your first two weeks of taking duloxetine

Discussion: Anyone here dealing with peripheral neuropathy?

Support Group: Neuropathy

Posted: Oct 1, 2018

Me too, Jerid -- I refuse to take hard drugs ... I know I may have...

https://connect.mayoclinic.org/comment/99166/

My Pain Specialist added Duloxetine ... it would if I were not taking the Duloxetine

Discussion: Chronic Pain members - Welcome, please introduce yourself

Support Group: Chronic Pain

Posted: Oct 3, 2020

I’m taking Duloxetine with Gabapenten….and I think it eases the burning in my lower legs. I...

https://connect.mayoclinic.org/comment/699000/

I’m taking Duloxetine with Gabapenten

Discussion: Has anyone tried anti-depressant medication for neuropathic pain?

Support Group: Neuropathy

Posted: Apr 14, 2022

Addition to my comment above. My Duloxetine tablets are 60 mg each. I’m on the highest...

https://connect.mayoclinic.org/comment/1252429/

My Duloxetine tablets are 60 mg each

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: Mar 7, 2025

I started with Duloxetine by itself and had to add Gabapentin as my feet would not...

https://connect.mayoclinic.org/comment/737776/

I started with Duloxetine by itself

Discussion: Looking to connect with people who have non-diabetic neuropathy

Support Group: Neuropathy

Posted: Aug 15, 2022

I have severe SFN over the entire body for a good 9 years probably contracted through...

https://connect.mayoclinic.org/comment/990132/

I've been on 60mg Duloxetine and ... I started duloxetine again on 60mg and ... worse or I developed tolerance to duloxetine

Discussion: Ideas for pain relief from Small Fiber Neuropathy (SFN)

Support Group: Neuropathy

Posted: Jan 2, 2024

Here’s a good review of duloxitine. It may provide some answers and advice. https://en.wikipedia.org/wiki/Duloxetine, the generic...

https://connect.mayoclinic.org/comment/715786/

Here’s a good review of duloxitine. ... https://en.wikipedia.org/wiki/Duloxetine

Discussion: Who else has Autonomic Neuropathy?

Support Group: Neuropathy

Posted: Jun 9, 2022

Why would anyone start on Cymbalta if Eli Lilly discontinues it? Start with another version of...

https://connect.mayoclinic.org/comment/1203039/

Start with another version of duloxetine

Discussion: Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Support Group: Chronic Pain

Posted: Jan 3, 2025

Thank you Rachel @rwinney for your reply. As in your case, my doctor wants me to...

https://connect.mayoclinic.org/comment/157839/

start with 30mg of extended release Duloxetine ... currently taking and did you feel that the Duloxetine

Discussion: Living with Neuropathy - Welcome to the group

Support Group: Neuropathy

Posted: Sep 7, 2019

I have taken those too. For a few years. Gabapentin and Duloxetine at night and Gabapentin...

https://connect.mayoclinic.org/comment/734127/

Gabapentin and Duloxetine at night and

Discussion: Gabapentin and Cymbalta

Support Group: Neuropathy

Posted: Aug 4, 2022

I did quit taking the Duloxetine entirely. It was affecting my appetite; which I couldn’t afford...

https://connect.mayoclinic.org/comment/683552/

I did quit taking the Duloxetine entirely

Discussion: What's your experience with duloxetine (US Brand Name; Cymbalta)?

Support Group: Depression & Anxiety

Posted: Feb 22, 2022

@sueinmn I will definitely pay attention medication like that. What does duloxetine do for you is...

https://connect.mayoclinic.org/comment/1234363/

What does duloxetine do for you is it

Discussion: Can’t get Asthma under control

Support Group: Asthma & Allergy

Posted: Feb 11, 2025

Hello @d13 I'm sorry to hear that you had to give up on the Duloxetine. I...

https://connect.mayoclinic.org/comment/676103/

hear that you had to give up on the Duloxetine ... I have been able to take the Duloxetine

Discussion: Internal Body Tremors and Tinnitus

Support Group: Brain & Nervous System

Posted: Jan 29, 2022

Hi, @marleneace - I imagine you were very relieved to make that transition from venlafaxine (Effexor)...

https://connect.mayoclinic.org/comment/124131/

transition from venlafaxine (Effexor) to duloxetine ... Mayo Clinic Connect discussion on duloxetine

Discussion: Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)

Support Group: Depression & Anxiety

Posted: Jan 8, 2019