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Comments (2,477)

Hi, I have had RA for 10 years. I was first diagnosed with Hashimoto’s Thyroiditis. One...

https://connect.mayoclinic.org/comment/145473/

plaquenil and within 1 month added methotrexate ... I now take 7.5 mg Rasuvo (methotrexate

Discussion: Rheumatoid Arthritis (RA) - Introduce yourself and meet others

Support Group: Autoimmune Diseases

Posted: Sep 25, 2019

I have Vexas. I was diagnosed within the last year or so. Was on methotrexate and...

https://connect.mayoclinic.org/comment/1312864/

Was on methotrexate and it didn'

Discussion: Has anyone heard of VEXAS syndrome?

Support Group: Blood Cancers & Disorders

Posted: May 25, 2025

Thank you for saying that, because I am still dealing with PMR, and do not want...

https://connect.mayoclinic.org/comment/780956/

What is the methotrexate?

Discussion: Can PMR (Polymyalgia Rheumatica) be induced by vaccine?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Dec 4, 2022

Methotrexate injections weekly work for me, along with folic acid daily. Stay away from Actemra, nasty...

https://connect.mayoclinic.org/comment/1237220/

Methotrexate injections weekly work

Discussion: New to PMR diagnosis

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Feb 15, 2025

The key is good rheumatologist. Many knee jerk to methotrexate as a therapeutic trial rather than...

https://connect.mayoclinic.org/comment/1243099/

Many knee jerk to methotrexate as a

Discussion: PsA or NOT PsA? Any ideas??

Support Group: Autoimmune Diseases

Posted: Feb 22, 2025

@theodorastronger perhaps you could ask if you could take the Methotrexate in pill form which you...

https://connect.mayoclinic.org/comment/1160231/

you could ask if you could take the Methotrexate

Discussion: Starting dosage of methotrexate?

Support Group: Autoimmune Diseases

Posted: Oct 21, 2024

https://connect.mayoclinic.org/comment/1091941/

Was taking methotrexate to lower immune

Discussion: Esophageal Lichen Planus

Support Group: Autoimmune Diseases

Posted: Jun 22, 2024

Thanks. Apparently it is not yet approved in Canada. I have recently started Methotrexate, however I...

https://connect.mayoclinic.org/comment/1288319/

I have recently started Methotrexate

Discussion: What is the goal when tapering?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Apr 23, 2025

I have lichen planus. I took methotrexate for 2 Mos and took myself off. I've never...

https://connect.mayoclinic.org/comment/1442465/

I took methotrexate for 2 Mos and took ... I also took folic acid with the methotrexate

Discussion: Anyone using Methotrexate for treating Lichen Sclerosis?

Support Group: Autoimmune Diseases

Posted: Nov 19, 2025

@captainkenny I have been on Actemera infusions once a month for my GCA. I also have...

https://connect.mayoclinic.org/comment/1441519/

Methotrexate did not do anything for

Discussion: Giant cell arteritis:I’m afraid and would appreciate any advice

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Nov 18, 2025

Not yet I am very afraid to start due to the horrible side effects My CRP...

https://connect.mayoclinic.org/comment/645017/

My CRP is 25 and I am still taking methotrexate

Discussion: Has anyone tried the medication leflunomide?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Oct 14, 2021

@bio - I feel for you! I thought my psoriasis was bad, but yours looks far...

https://connect.mayoclinic.org/comment/717357/

me - cleared all my psoriasis - was Methotrexate ... Then I was reduced to 6 tablets of Methotrexate ... dermatologist reduced my dose to 4 Methotrexate ... tell if it will be as effective as Methotrexate ... Ask your dermatologist if Methotrexate

Discussion: Psoriasis: What treatment helps?

Support Group: Skin Health

Posted: Jun 14, 2022

Depends on how much you value your only liver. And make no mistake, I did enjoy...

https://connect.mayoclinic.org/comment/1127764/

I was on Methotrexate for RA between ... Enbrel instead of Humira, and began methotrexate ... No Methotrexate. ... But the insurance companies like methotrexate ... And methotrexate.

Discussion: Methytrexate and alcohol

Support Group: Autoimmune Diseases

Posted: Aug 20, 2024

I am currently on 2.5 mg of Methotrexate / 6 tablets 1 day a week --...

https://connect.mayoclinic.org/comment/681010/

I am currently on 2.5 mg of Methotrexate ... Folic ------------- I have been on the Methotrexate

Discussion: Experience with Methotrexate?

Support Group: Polymyalgia Rheumatica (PMR)

Posted: Feb 15, 2022

Doctor keeps encouraging me to try Methotrexate and I keep resisting. I would like some anecdotal...

https://connect.mayoclinic.org/comment/651801/

Doctor keeps encouraging me to try Methotrexate ... 10 years and all my blood work that methotrexate