Primary Sclerosing Cholangitis (PSC)

Welcome to the online home of the Chris M. Carlos and Catherine Nicole Jockisch Carlos Endowment for Primary Sclerosing Cholangitis (PSC). Thanks to support provided by this endowment, dedicated Mayo Clinic investigators and their teams are making strides to better understand and treat PSC patients, with the ultimate goal of developing a cure for this disease.

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PUBLIC PAGE
Sep 9, 2019

Mayo Clinic PSC Abstracts Accepted for the 2019 Annual AASLD meeting

By Konstantinos N. Lazaridis, M.D., @klazaridis

AASLD Doctor with Stethoscope image

The American Association for the Study of Liver Disease (AASLD) is the leading society of scientists and health care professionals in the United States committed to preventing, diagnosing, and treating liver disease. During the annual AASLD meeting that will take place in Boston, MA (November 8-12, 2019) our group has submitted five scientific abstracts, which have being accepted for presentation. Accepted abstracts represent high caliber work, which will be shared with other scientists and health care professionals. Our work that was accepted for this meeting ranges from discovery, to translation, and to clinical application. We are very excited to share with our followers this work on PSC.

Abstract 1: Changes in Liver Stiffness Measured by Magnetic Resonance Elastography are Associated with Outcomes in Primary Sclerosing Cholangitis

Presenter: John E. Eaton, M.D.

Presentation Type: Poster Presentation
Presentation Date(s)/Time(s):

Friday, November 8: 8:00 am – 5:30 pm; Presenters Available: 12:30 – 1:30pm
Saturday, November 9: 2:00 pm–7:00 pm; Presenters Available: 5:15 – 6:15pm
Sunday, November 10: 8:00 am – 5:30 pm; Presenters Available: 12:30 – 1:30pm
Monday, November 11: 8:00 am – 5:30 pm; Presenters Available: 12:30 – 1:30pm

Location: Hynes Convention Center, Hall B

Financial Support: Chris M. Carlos and Catharine Nicole Jockisch Carlos Endowment Fund in Primary Sclerosing Cholangitis

 

Abstract 2: Therapeutic Targeting of Ductular Reactive Cells in Cholestatic Liver Disease

Presenter: Adiba I. Azad, M.D.

Presentation Type: Oral Presentation
Presentation Date/Time: Monday, November 11th at 5 p.m.

Location: Room 210, Hynes Convention Center

Financial Support: Chris M. Carlos and Catharine Nicole Jockisch Carlos Endowment Fund in Primary Sclerosing Cholangitis

 

Abstract 3: Modulation of the Intestinal Microbiome Alters Disease Progression in Germ Free Rodent Models of Primary Sclerosing Cholangitis

Presenter: Steven P. O'Hara, Ph.D.

Presentation Type: Poster Presentation

Presentation Date(s)/Time(s):

Friday, November 8: 8:00 am – 5:30 pm; Presenters Available: 12:30 – 1:30pm
Saturday, November 9: 2:00 pm–7:00 pm; Presenters Available: 5:15 – 6:15pm
Sunday, November 10: 8:00 am – 5:30 pm; Presenters Available: 12:30 – 1:30pm
Monday, November 11: 8:00 am – 5:30 pm; Presenters Available: 12:30 – 1:30pm

Location: Hynes Convention Center, Hall B

Financial Support: DK57993, DK84567, Chris M. Carlos and Catharine Nicole Jockisch Carlos Endowment Fund in Primary Sclerosing Cholangitis

 

Abstract 4: Bile Acid Profiles Predict Hepatic Decompensation in Primary Sclerosing Cholangitis

Presenter: Omar Y. Mousa, M.B.B.S.

Presentation Type: Oral Presentation
Presentation Date/Time: Monday, November 11th at 10:45 a.m.

Location: Constitution Ballroom, Hynes Convention Center

Financial Support: DK118619, Chris M. Carlos and Catharine Nicole Jockisch Carlos Endowment Fund in Primary Sclerosing Cholangitis, and PSC Partners Seeking A Cure

 

Abstract 5: Transcription Factor, ETS1, Interacts with Histone Acetyl Transferase, p300, Promoting the Anti-Apoptotic Phenotype of Senescent Cholangiocytes via Induced Transcription of the Pro-Survival Gene, BCL2L1

Presenter: Patrick L. Splinter, M.S.

Presentation Type: Oral Presentation
Presentation Date/Time: Sunday, November 10th at 5 p.m.

Location: Room 210, Hynes Convention Center

Financial Support: DK57993 and Chris M. Carlos and Catharine Nicole Jockisch Carlos Endowment Fund in Primary Sclerosing Cholangitis

 

Read the full abstracts from the PSC team here.

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