Primary Sclerosing Cholangitis (PSC)

Welcome to the online home of the Chris M. Carlos and Catherine Nicole Jockisch Carlos Endowment for Primary Sclerosing Cholangitis (PSC). Thanks to support provided by this endowment, dedicated Mayo Clinic investigators and their teams are making strides to better understand and treat PSC patients, with the ultimate goal of developing a cure for this disease.

Follow the PSC page and stay up-to-date as we post news about advances in PSC research, clinical trials, and available resources.

PUBLIC PAGE
Apr 8, 2019

Validation of the PREsTo machine learning algorithm for the prediction of disease progression in patients with PSC

By Ethan McConkey, Moderator @ethanmcconkey
In an abstract presented this week at the 2019 European Association for the Study of the Liver (EASL) meeting in Vienna, Austria, Dr. John Eaton from Mayo Clinic, Rochester, MN, reported the confirmation of the PREsTo machine learning algorithm for the prognostication of disease progression in a randomized trial [...]
Validation of the PREsTo machine learning algorithm for the prediction of disease progression in patients with PSC
Mar 25, 2019

15th annual conference for PSC patients and caregivers in Rochester, MN

By Konstantinos N. Lazaridis, M.D. @klazaridis
We are privileged to host in Rochester, Minnesota the 15th annual conference for PSC patients and their caregivers (June 20-23, 2019). In a partnership with the PSC Partners Seeking a Cure we have created an exciting and informative program (please see the attached agenda). During this conference, we will highlight our current state of-the-art research efforts, and [...]
15th annual conference for PSC patients and caregivers in Rochester, MN
Mar 11, 2019

PSC Investigator Profile: Ravishankar Iyer, Ph.D.

By Ethan McConkey, Moderator @ethanmcconkey
In the early 1980s, Ravi Iyer, Ph.D., helped usher in a new application of artificial intelligence, one marked by the ability to predict when individual machines would fail. At the time, computer scientists had developed systems allowing machines to perform tasks normally requiring human intelligence, such as speech recognition [...]
PSC Investigator Profile: Ravishankar Iyer, Ph.D.
Feb 25, 2019

Rare Disease Day February 28th, 2019

By Konstantinos N. Lazaridis, M.D. @klazaridis
This Thursday, February 28th, we celebrate: "Rare Disease Day". Therefore, we dedicate this week's post to the anniversary of Rare Disease Day in an effort to raise awareness about rare diseases. Rare diseases are individually rare but collectively common. In the United States, a “rare disease” is defined [...]
Rare Disease Day February 28th, 2019
Feb 11, 2019

PSC Investigator Profile: Tom Hemming Karlsen, M.D., Ph.D.

By Konstantinos N. Lazaridis, M.D. @klazaridis
A decade ago, Tom Hemming Karlsen, M.D., Ph.D., who leads the Norwegian PSC Research Center (NoPSC), joined forces with Konstantinos Lazaridis, M.D., of Mayo Clinic to uncover the culprits driving PSC. At the time, neither could have foreseen the transformative power of their collaborative genetic study on the global [...]
PSC Investigator Profile: Tom Hemming Karlsen, M.D., Ph.D.

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