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Welcome to the online home of the Chris M. Carlos and Catherine Nicole Jockisch Carlos Endowment for Primary Sclerosing Cholangitis (PSC). Thanks to support provided by this endowment, dedicated Mayo Clinic investigators and their teams are making strides to better understand and treat PSC patients, with the ultimate goal of developing a cure for this disease.
Follow the PSC page and stay up-to-date as we post news about advances in PSC research, clinical trials, and available resources.
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Human environmental exposures and corresponding metabolic responses are highly variable, and may contribute to disease in genetically susceptible individuals. Recently, ultra-high resolution mass spectrometry (HRMS)…
Primary Sclerosing Cholangitis (PSC) often strikes without a patient noticing any symptoms or signs of disease. For Nicole Jockisch Carlos, an Atlanta resident, this was…
When Dr. Nicholas LaRusso arrived at Mayo Clinic for a three-month elective during his fourth year of medical school, he knew where he wanted to…
In an effort to better predict the outcomes for Primary Sclerosing Cholangitis (PSC) patients, Mayo Clinic researchers have created a new tool called the Primary…
A Mayo Clinic-led research consortium recently received a significant, five-year grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study…
Having trained at the National Human Genome Research Institute (NHGRI) in the early 2000s, Konstantinos N. Lazaridis, M.D., is no stranger to sifting through sequences…
Although researchers have known for several decades that about 75% of patients with Primary Sclerosing Cholangitis (PSC) also suffer from Inflammatory Bowel Disease (IBD), whether…
A major goal of our current research for Primary Sclerosing Cholangitis (PSC) involves capturing “the exposome,” or the role of environmental exposures – pollutants,…
Dr. Gregory Gores knows first-hand the importance of training the next generation of physician scientists interested in Primary Sclerosing Cholangitis (PSC). It was during his…
Aided by the advent of the high-throughput data measurement era, systems biology approaches are ushering in a new period within Primary Sclerosing Cholangitis (PSC) research.…
Dr. Angela Cheung, the first Carlos PSC Research Program fellow, explains a new area of research – epigenomics – and what it means for…
Thanks to generous support provided by the Chris M. Carlos and Catherine Nicole Jockisch Carlos Primary Sclerosing Cholangitis (PSC) Endowment, Mayo Clinic’s PSC research team…
For more than four decades, the Mayo Clinic Division of Gastroenterology and Hepatology has led the field in clinical and scientific discoveries related to…
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