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Discussions (308)
Just joined, biopsy shows 4+4 (Group 4)
My rising PSA, 5 years after Proton treatment prompted a PSMA/PET scan, followed by biopsy at Johns Hopkins. Biopsy shows 4+4 (Group 4) cancer, Can...
New (to me) PCRI Resource and 2022 review
Background: I had PBT therapy in early 2020; with a PSA of 8.3, and I did a 4 month course of ADT. When I was...
Additional radiation treatment for 2nd recurrence
My PSA was 5.53 and my Gleason score was 3+4 =7. I had a robotic prostatectomy in 2006. Went undetectable until 2013. I then Had...
ADT before surgery: Good idea?
I have been working with 3 COE’s . I have decided on surgery. 62 yrs G9, non metastatic, localized PC. PSMA pet 2/10th. Surgery 3/26....
IRE for biorecurrence of PC confined to prostate—any thoughts?
My lesion is right anterior mid-gland, a biorecurrence after Proton therapy at JH 5 years ago. Current biopsy and PSMA/PET showed no spread. My Gleason...
Rise in PSA after 4 years on ADH & Zytiga
My first post with this group. My PS has been.007 undetectable for 4 years. It has now rose to .19 . Dr ordered a PSMA...
New to the prostate cancer club
New to the club: I figured that I would get started with my reading and research to help guide my Journey here.Bio:Age 50, Weight 185,...
Radical Prostatectomy vs. Radiation therapy?
I'm a 65 year old very active workaholic male. I have a 100+ year old restaurant that is/was family owned and operated. Now there is...
Monitoring PSA post surgery with Gleason 9
49 yo, Gleason 9, surgery in 6 weeks. My PSA was around 1 for years and then in Jan ‘25 went to 4.3. Seems like...
What does Capsular Invasion mean? What are the next treatment options?
I’m having recurrence after triplet treatment (Lupron and darolutamide, then Chemo, then IMRT) for Gleason 9 metastatic. Thirteen months of Lupron ended last February. Continuing...
Pre diagnosis function considerations
My research starting down this road is leading me towards some conclusions to bounce off others here. I have been on AS for about 4...
PET scan explanation, findings & personal conclusion
Background: Diagnosis of prostate cancer 2010. Gleason 3+3; PSA: 6.46 noted as slow growth cancer. Underwent proton radiation therapy at Loma Linda Hospital, a pioneer...
Quandry on my chosen pathway
I was diagnosed with PC late Dec .2025 at Mayo, MN. 1 smaller lesion, PSMA shows no spread. I decided I would do radiation SBRT...
Recurrence in pelvic lymph node
I'm meeting with my radiologist this week, and would appreciate your suggestions about questions I should ask. After a prostatectomy five years ago (Gleason 8),...
12 Days of Christmas greetings
(First diagnosis fall, 2024) In the first year of treatment, my prostate gave to me… A warning from PSA 2 toasted gonads 3 positive samples...
Is PSA rise inevitable after hormone therapy?
In 2024 I had a prostatectomy & PSA rose, am a Gleason 9, stage 4. PSMA detected lung nodules (only area) that disappeared after Eligard...
Oligo metastatic PC detected
Detected oligo metastatic ( low volume) prostate cancer on 11/08/25. Gleason score 8. PSMA PET shows Meta sized to Left testicle, left acetabulum , para...
Dealing with metastatic prostate cancer and other health issues
My husband (85 years old and loves his quality of life) was diagnosed with metastasized prostate cancer in March 2025: stage 4 and Gleason of...
New Blood Test Detects 50 Types of Cancer at an Early Stage
https://grail.com/our-products/ Three days ago my GP recommended the Galleri blood test which one pays for out of pocket. She told me that it picks up...
Need Radiotherapy guidance
Hi I went for RP last year Feb-2022. The pathology report came with a Gleason score of 3+5 and one pelvic node positive. PSA test...
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