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@thomasmichael, here are other discussions where members mention treatment with bicalutamide (Casodex) - https://connect.mayoclinic.org/group/prostate-cancer/?search=casodex&index=discussions

https://connect.mayoclinic.org/comment/1208576/

Discussion: Prostate cancer treatment choices

Support Group: Prostate Cancer

Posted: Jan 10, 2025

Fellow cancer patient here just weighing in with what I’ve been able to find. My doctor...

https://connect.mayoclinic.org/comment/1120373/

Discussion: Does ADT actually kill cancer cells?

Support Group: Prostate Cancer

Posted: Aug 8, 2024

My understanding is that Casodex blocks testosterone from getting into cancer cells while drugs like Lupron...

https://connect.mayoclinic.org/comment/1120148/

Discussion: Does ADT actually kill cancer cells?

Support Group: Prostate Cancer

Posted: Aug 8, 2024

@jeffmarc Jeff, can you please explain that protocol and if it is always the case, or...

https://connect.mayoclinic.org/comment/1401114/

Discussion: 44yr PSA180 Gleason9 non-metastatic. Surgery or Treatment?

Support Group: Prostate Cancer

Posted: Sep 25, 2025

Hi @starman, I’m not sure that anyone could make a definitive connection between Casodex (bicalutamide), cardiac...

https://connect.mayoclinic.org/comment/938196/

Discussion: Casodex: ADT Side Effects and Cardiac Issues?

Support Group: Prostate Cancer

Posted: Sep 28, 2023

For those who don’t start on Orgovyx (because some insurances here in the U.S. either won’t...

https://connect.mayoclinic.org/comment/1346711/

Discussion: Husband’s low psa, aggressive Gleason 8

Support Group: Prostate Cancer

Posted: Jul 12, 2025

That can happen. Did they start him on Casodex (Bicalutimide) prior to his Lupron injections?

https://connect.mayoclinic.org/comment/1470124/

Discussion: My husband's PSA rose after two Lupron treatments. Thoughts?

Support Group: Prostate Cancer

Posted: Dec 29, 2025

Received hormone treatment with casodex. Sixty days later diagnosed with heart failure. Stopped casodex. Received a...

https://connect.mayoclinic.org/comment/998497/

Discussion: Overwhelming fear after undetectable to slightly detectable psa

Support Group: Prostate Cancer

Posted: Jan 16, 2024

Casodex 30 days next then Zolodex 3 Mos injection

https://connect.mayoclinic.org/comment/916756/

Discussion: Enzalutamide (Xtandi): Anyone have experience with this drug?

Support Group: Prostate Cancer

Posted: Aug 21, 2023

@grandpun Did you take any ADT "optimizers" with your Lupron shots? Like Zytiga, Nubeqa, or old...

https://connect.mayoclinic.org/comment/1502586/

Discussion: Weighing the cancer risk reduction & quality-of-life cost of ADT?

Support Group: Prostate Cancer

Posted: Feb 10 1:57pm

Finally met with Urologist and Oncologist. Plan is to do 30 days of Casodex, get CT...

https://connect.mayoclinic.org/comment/774963/

Discussion: Metastatic Prostate Cancer: Where do I go from here?

Support Group: Prostate Cancer

Posted: Nov 19, 2022

@dinu Trenantone Is just Lupron with another name. Did they give you Casodex (Biclutamide) first? You...

https://connect.mayoclinic.org/comment/1401077/

Discussion: 44yr PSA180 Gleason9 non-metastatic. Surgery or Treatment?

Support Group: Prostate Cancer

Posted: Sep 25, 2025

I don’t want ADT either. Lucky I do not have pain yet. Cancer moved to my...

https://connect.mayoclinic.org/comment/1003798/

Discussion: Prostate Cancer Warriors Support Group - Wednesdays nights

Support Group: Prostate Cancer

Posted: Jan 25, 2024

I have been on Lupron for 22 years. In the beginning, PSA rose a tad ,...

https://connect.mayoclinic.org/comment/955296/

Discussion: Treatment for Prostate Cancer Metastasized to Bones

Support Group: Prostate Cancer

Posted: Oct 28, 2023

Casodex is a 1st generation anti-androgen, or bio-genesis inhibitor. The only place I see it being...

https://connect.mayoclinic.org/comment/1098023/

Discussion: ADT as a stand alone treatment

Support Group: Prostate Cancer

Posted: Jul 2, 2024

@brianjarvis Yes, I can see how a flare could cause some harm. But this flare situation...

https://connect.mayoclinic.org/comment/1482224/

Discussion: ADT injection: Benefits worth the toll it will take on my body?

Support Group: Prostate Cancer

Posted: Jan 14 1:07pm

Hi Gently, Can u pls tell me the source of your info on Casodex? My cancer...

https://connect.mayoclinic.org/comment/1202027/

Discussion: How do you decide whether to take part in a study group?

Support Group: Prostate Cancer

Posted: Jan 1, 2025

With Casodex and Lupron I'm starting to grow my very own set of boobs! But for...

https://connect.mayoclinic.org/comment/1172330/

Discussion: Prostate cancer humor?

Support Group: Prostate Cancer

Posted: Nov 12, 2024

My T levels always Rise considerably when taking Casodex. (over 1000) but PSA drops usually in...

https://connect.mayoclinic.org/comment/1120123/

Discussion: Does ADT actually kill cancer cells?

Support Group: Prostate Cancer

Posted: Aug 8, 2024

I seem to remember Dr Shultz of PCRI fame mentioning that while uncommon, Casodex as a...

https://connect.mayoclinic.org/comment/1097675/

Discussion: ADT as a stand alone treatment

Support Group: Prostate Cancer

Posted: Jul 1, 2024

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