Zometa infusions to help prevent bone loss from cancer treatments

Posted by trixie1313 @trixie1313, Jun 13, 2019

Has anyone had Zometa infusions to help combat the effects of aromatase inhibitors (bone loss). I have osteoporosis of my spine and osteopenia of the hip and am told I need this to prevent future fractures.

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I had my first Zometa infusion in August of this year. Really no instructions other than hydrate. I’ll ask my oncologist about Claritin & Tylenol. I was fine after infusion. Felt no different. No side effects. I will do infusions every 6 months.
Just a question: do you think that side effects occur due to the speed of the infusion. My infusion started w/ a liquid/saline (???) for about 20-30 minutes snd then they put the Zometa bag on. I have no basis of procedure as this was my first.

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I'm not taking an AI. I have been on Tamoxifen for 6 months. I'm 41 and have been having pain in my hips and knees. I'm not sure if it's age related or possibly a side effect. I have a desk job so I try to get in 10,000 steps a day. I keep reading exercise is the key to help with joint pain. Have any of you had Zometa with Tamoxifen? Did it help with joint pain? Thanks!

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@sequoia

I had my first Zometa infusion in August of this year. Really no instructions other than hydrate. I’ll ask my oncologist about Claritin & Tylenol. I was fine after infusion. Felt no different. No side effects. I will do infusions every 6 months.
Just a question: do you think that side effects occur due to the speed of the infusion. My infusion started w/ a liquid/saline (???) for about 20-30 minutes snd then they put the Zometa bag on. I have no basis of procedure as this was my first.

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Yes! I would get flu like sickness after and my oncologist had them slow the drip down to over 65 minutes instead of 30 and it made a world of difference. No SE at all after that.

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@nikki727

Yes! I would get flu like sickness after and my oncologist had them slow the drip down to over 65 minutes instead of 30 and it made a world of difference. No SE at all after that.

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That’s good to know & I’m sure others will find your information very helpful. Thanks for posting this & im glad it helped you with the Dick effects. Blessings

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Upcoming Zometa infusion: I was told to take Claritin 1 week before + 1 week after infusion because it will help prevent or lessen potential bone pain. Also, thanks to this discussion group, I asked what time frame / infusion speed was ordered, and I was told my session is scheduled for 90 minutes. How much of that is prep, how much actual infusion, I don’t know, but it definitely sound like a slow and steady pace.

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@ellerbracke

Upcoming Zometa infusion: I was told to take Claritin 1 week before + 1 week after infusion because it will help prevent or lessen potential bone pain. Also, thanks to this discussion group, I asked what time frame / infusion speed was ordered, and I was told my session is scheduled for 90 minutes. How much of that is prep, how much actual infusion, I don’t know, but it definitely sound like a slow and steady pace.

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Thanks for sharing about the Claritin, isn’t that interesting. I bet you that there are others here who will benefit from that information.

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@auntieoakley : Quick update: had first Zometa infusion yesterday morning. No problems, if you don’t count the usual frustrating rummaging for a vein. 3 attempts in different locations, so about par for the course. Otherwise no issues. No pain, and amazingly not even a bruise at the injection site (quite unusual, mostly I look like a horse kicked me after surgery IV lines). Now just hoping Zometa does it’s job.

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@ellerbracke

@auntieoakley : Quick update: had first Zometa infusion yesterday morning. No problems, if you don’t count the usual frustrating rummaging for a vein. 3 attempts in different locations, so about par for the course. Otherwise no issues. No pain, and amazingly not even a bruise at the injection site (quite unusual, mostly I look like a horse kicked me after surgery IV lines). Now just hoping Zometa does it’s job.

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Yippee! I have pretty much the same experience. But I never knew about the Claritin. Celebrate taking the best care of you that is possible.

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@auntieoakley

No one mentioned it to me either, until my oncologist retired and I started seeing my husbands wonderful oncologist. He said geez I sure would hate to see you get a compression fracture and after I had an accident and everything broke two years before. It seemed like my pcp would have picked up on it. Thanks be to Mayo trained doctors!
You will need to advocate for yourself in this. If your doctor won’t listen, I would humbly suggest a second opinion might be in order. Maybe this drug isn’t right for you, but pretending there is no problem certainly can’t be the best plan for you either.

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My oncologist mentioned the bone density issue at the meeting when he recommended anastrozole. We went over the major side effects. I gather the issue is less that the drug causes this than that estrogen depletion does. But maybe the aromatase inhibitors exacerbate the bone loss?

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A friend suffered a broken neck, one that was too risky for surgery, and he wore a carbon-fiber 'halo' for 2 years. I took him a calcium/D3/K2 supplement when he was in the hospital. The neurosurgeon read the label the following day and commented that the K2 was particularly important in bone healing and protects against calcium building up the arteries. My cardiologist also said that K2 seems to do that according to recent studies. My friend fully healed, though the neck vertebrae were in fragments when first injured. I don't know that the K2 helped but the surgeon was pleased with the rate of healing of a very bad injury.

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