Who has been on Prolia and hasn’t had any bone density gains.

Hi @kristie2 . I'm supposed to start Evenity in a couple of weeks. My rheumatologist wants me to do 1-2 years of Prolia afterwards & then a few years of Reclast & then done. I don't want to do Prolia at all. The official Prescription Guide for Evenity has a chart with relative risk reduction for a new vertebral fracture & it states 73% reduction after one year of Evenity & a 75% reduction after one year of Evenity & then one year of Prolia. That doesn't sound like much of a difference that would encourage me to try Prolia. I hope you get more responses. I'd like to know, too.

I have to say that after taking Prolia for one year and my DEXA showed zero improvement. I guess that I fall in the category of 5% of people who fail with Prolia. The average gain is 5-6% in the first year. I would have never taken it if I knew. I was so against it but my endocrinologist convinced me that was the way to go. I must admit that I had no side effects and taking it for a short amount of time you’re not going to rebound when you switch to reclast. It seems to be the new protocol after taking Evenity. I had a great improvement with Evenity my T score in my spine was -4.6 after the year it was -3.3.
By the time you are do to take Prolia they may have a new protocol and it may work for you.

I was on Prolia for several years with minimal improvements before beginning Evenity (3 months now). I don’t know that going back on Prolia after I complete the 12 months of Evenity would be beneficial for me. I’ll have that discussion with my doctor before I complete the cycle of Evenity.

I most likely will go on reclast. Will find out tomorrow .

I also had zero gain with Prolia. Evenity brought my spine from -4.6 to -3.0. Previous endo said Prolia could improve it more so I agreed to 4 injections. No gain at all. I just switched to Reclast and have had unpleasant side effects, so not sure what’s next. Wish I could repeat Evenity, it’s the only med that’s helped at all.

@neesie0159 I went from -3.3 to -3.2 after 2 injections of prolia. I was switched after one year of Evenity. I then decided that prolia really didn’t work for me and went on Reclast. Now I’m at -3. After one year of reclast and most likely will do another year of reclast.

I just received my third injection of Prolia Yesterday. Previously, I had been on Fosamax But because I was having a hip replacement, I felt the prolia would be better at building bone Afterwards. My DEXA scan after a full year of Perlia showed an increase in my hip of 7.3% and 15.1% in my lumbar spine. I am still waiting for the doctor to get back to me because of arthritis in my lumbar spine I know it will not be a true 15.1% increase. The disappointment is that my forearm has gotten no better from the pro Leah, which I thought it would. My previous bone density in my arm was 4.1, now it is 4.4. So no improvement despite the fact that I work out with weights.