What's next?

Posted by sheridanb @sheridanb, Feb 26 11:30am

Folfirinox showed resistance after about 9 or 10 months. Now gem/abrax may be going the same route as CA19-9 numbers have gone from 300 to 800 in the last couple months. Scans are happening next week.... MRI's on 3 parts of his back, and brain, and CT on full body. I am aware the scan results are more important than the CA19-9 numbers... but I'm worried for my husband. Last time the numbers went up the scans did show new growth.
So, what options are next. Can he go back to folfirinox? Or are there other chemo drugs for pancan? I really hate to think about the folfirinox as it was really, really, really hard on him... losing weight and turned into a zombi. Dizziness and severe neuropathy have been a big issue with gem/abrax, but at least he can hold a conversation.
Yes, I'm concerned. Thanks.

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Update: The scans all looked good despite the CA19-9 numbers going up the last couple months. But side effects from chemo have gotten severe enough that our oncologist feels it is time for a little break from chemo... extra hydration... and start looking at the possibility of trials. We'll see the dr in a couple weeks. He says my husband has been a "real trooper" to be on chemo without a break for so long, and just feels he needs a break to see if he can recover some. But also knows that with the rising numbers that something... not yet in the scans... may be happening, so trials may be able to help.

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