How did you wean off Metoprolol?

Posted by kenny48 @kenny48, May 11, 2018

Hi,
I've been taking both flecainide and metoprolol now for eight years, as a prophylactic for Afib. I recently moved to North Carolina and have a new Cardiologist. Have had a lot of PVC's this past two months, and had to wear a heart monitor for an entire month. He said that although I had a lot of PVC's I didn't have even one PAC! He also noted that my BPM was low in the low fifties most of the time. He asked why I was taking metropolol. I told him that the only thing my previous doctor had said was " it makes the flecainide, work better". He suggested I stop taking the metoprolol to see how I do without it. Unfortunately I read a lot of information on the internet. I read that it can be very dangerous to stop taking it. I take 25 mg metoprolol succinate, split in half. Once in the morning with my flecainide, and then again in the evening for a second dose. He wants me to take half in the morning and skip the evening dose for two days, then stop entirely. Has anyone else stopped taking this drug in a similar manner? I'm worried that the cut off is too soon.

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Profile picture for haygood @haygood

I have a question about weaning off Metropoplol tartrate. I have been taking this med for approximately 6 years. It was started when I was having fluctuations of hypertension and heart palpitations. For about two years, I've been so fatigued and short of breath that I could hardly function. In the last month, it has become so bad that I can't do anything physical. My cardiologist said that I have no heart issues to cause this. I do have asthma which is pretty much controlled. I take 50 mgs of Losartan once a day, 2.5 mgs of amlodipine twice a day, and 12.5 Metropoplol tartrate twice a day. I called my cardiologist for an appointment to discus the meds with him and all I got was a call from his nurse to try discontinuing the metropoplol but to watch my blood pressure. Nothing about weaning off it but I did research and so I have just been taking 12.5 mgs once a day for 3 days. I am shaking, feel awful, blood pressure going up and down and am wondering if this is from lowering the dosage. I'm aware that I was already on a low dosage but I can be pretty sensitive to drugs. I have had problems with my blood pressure going to low and my pulse rate hardly ever goes over 50 and is sometimes in the 40's. If this continues, I will insist on an appointment and don't understand why they wouldn't give me an appointment to discuss this issue.

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I was taking 25 mg Metoprolol Tartrate and 2.5mg Amlodipine Besylate both twice a day. They are both for reducing blood pressure. the Amlodipine does not lower your heart rate like the Metoprolol does. My calves were mildly swollen from the Amlodipine. I had two incidents where my calves were hard as rocks.
I stopped the Amlodipine. The cardiologist said he was Ok with this but if my blood pressure goes over 140 take one Amlodipine. My systolic gets high but not my diastolic-usually in the 50's. My heart rate is usually in the 50's. My previous cardiologist told me since the diastolic was low not to take the metoprolol if the systolic goes below 120.
The generally accepted medical practice is to hold the Metoprolol is systolic is 110 or below or the heart rate is 60 or below. If I followed this for my heart rate I would never take it.
How high does your systolic get? Are you off all salt?
There are other drugs to lower it.
Here is an excellent article:
https://www.consumerreports.org/cro/2011/03/best-drugs-to-treat-high-blood-pressure/index.htm
There are7 pages (lower right)

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I have a question about weaning off Metropoplol tartrate. I have been taking this med for approximately 6 years. It was started when I was having fluctuations of hypertension and heart palpitations. For about two years, I've been so fatigued and short of breath that I could hardly function. In the last month, it has become so bad that I can't do anything physical. My cardiologist said that I have no heart issues to cause this. I do have asthma which is pretty much controlled. I take 50 mgs of Losartan once a day, 2.5 mgs of amlodipine twice a day, and 12.5 Metropoplol tartrate twice a day. I called my cardiologist for an appointment to discus the meds with him and all I got was a call from his nurse to try discontinuing the metropoplol but to watch my blood pressure. Nothing about weaning off it but I did research and so I have just been taking 12.5 mgs once a day for 3 days. I am shaking, feel awful, blood pressure going up and down and am wondering if this is from lowering the dosage. I'm aware that I was already on a low dosage but I can be pretty sensitive to drugs. I have had problems with my blood pressure going to low and my pulse rate hardly ever goes over 50 and is sometimes in the 40's. If this continues, I will insist on an appointment and don't understand why they wouldn't give me an appointment to discuss this issue.

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No, we can't know, Debra. We don't have your file, your history, nor what the prescribing Dr. has concluded about your circumstances, including if you are habituating to metoprolol. Heart arrhythmias like atrial fibrillation are progressive in nature. Because they progress, they tend to work their way out from under the first and second drugs prescribed to control your rate or your rhythm. At some point, the best advice is to treat the arrhythmia using mechanical means such as catheter ablation or a pacemaker. It's quite involved, and worth learning about, but most people find their medications becoming less effective over months and years.

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Yes...misspelled it....probably misspelled Carville too but the name brand for that is coreg.

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Profile picture for debra54 @debra54

I was on metetplol for 10 years and my 1st visit at heart doctors he took me off and put me on cardevlol...I had irregular heartbeat for a week....I got a 2nd opinion and doctors keep telling me that cardivlol is better for the heart than meterplol.

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Do you mean the drug Metoprolol?

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Does anybody know why doctors are steering away from metetplol and recommending cardivlol?

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I was on metetplol for 10 years and my 1st visit at heart doctors he took me off and put me on cardevlol...I had irregular heartbeat for a week....I got a 2nd opinion and doctors keep telling me that cardivlol is better for the heart than meterplol.

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Profile picture for rezon8r @rezon8r

Anyone who wants to ween off beta blockers should read my story.
I had a heart attack July 2015 and was placed on beta blockers (metoprolol). I was on 25mg to start, half a pill in morning and evening. Over a few months my pulse was dropping to 43 bpm and my BP was very low. My doctor recommended cutting the dose to half to see how I did. It helped a bit. (12.5mg) once a day.

About 2 months later - out of the blue, my heart started racing 155 bpm and my blood pressure spiked to 180/100. I had chest pain, difficulty breathing, sweating, dizzy... was positive I was having another heart attack. Off to the ER. They did ecg and trope, X-ray... all was fine and my symptoms abated over a few hours.

The next attack happened about 3 weeks later. Same thing. They gave me a hotter monitor and nothing. This went on for a year. I had several stress tests that said all was good. They prescribed lorazepam and told me it was anxiety attacks.
Sometimes my heart rate was 170+ and bp 225/130.
I was in hell. Doing vagel exercises and holding my breath in a bowl of ice cold water. The attacks started to get worse and more frequent. Sometimes waking me up at 4am. The lorazepam did nothing to abate - but still 4 cardiologists, a heart specialist and maybe 25 different doctors wrote it off to anxiety attacks. Yet, after almost 3 years of this, I had strong suspicion it was a rebound effect from the beta blocker.

I tried to ween off it very slow for 2 years. Once I was off for 3 1/2 weeks and then BAM, massive attack that actually registered a tiny trope test. So I had to go back on.

Finally, my heart specialist said let’s switch beta blockers- that metoprolol is a twice a day drug and I was only taking a small amount once a day. So we switched to bisoprolol 2.5mg (half a pill) once a day. This was in August 2018.

The attacks stopped completely. What was happening, yet nobody will admit, was the metoprolol was wearing off every evening before I took my next dose, or shortly after... my body started to produce adrenaline again, and since I had developed billions more adrenal receptors (from being on beta blockers - bodies reaction to the drug), my body would flip out and I would have a hypertension/tachycardia attack.

2 weeks later on the bishoprolol and I felt like crap. Dizzy, no energy, insomnia... but no attacks. Bp and pulse were low so we cut dose to 1.25mg. Felt like crap for a month... then started to feel a little better.
This January, I had had enough of feeling dizzy and no energy. One night my pulse went down to 40bpm and my BP was 190/110. Off to emergency I went. They did all the tests and nothing. So we decided to cut my dose to ween off. I was told by several doctors to just go off cuz it was such a small amount. But having read so much, I thought I should ween. So .65mg tiny thing.

It has been 2 weeks now and I’ve been to ER with crazy high BP twice - but it always comes back down after a few hours on its own. I keep having these attacks again and I’m 100% sure it’s caused by the beta blocker.

This time I’m going to power through even if it kills me. This is a nightmare drug and after almost 4 years of pure hell - I have had enough.

My understanding is although I may be off the drug for months at some point- there is still the physical manifestations of the extra adrenal receptors that will eventually deteriorate as my chemistry normals.

Couldn’t imagine doing this without God. Good luck everyone who is fighting this battle.

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I also had unexplained spikes in BP 250/130 and pulse over 200 with a bit of arrhythmia thrown in AF and VF which was rather exciting and lots of ambulances but it all calmed down without explanation whilst in A&E. It was happening about 4 times a year. Doctors increased the dose of bisoprolol which made the problem worse. This was whilst on bisoprolol and rivaroxaban and ramipril. I started feeling really rubbish and was feeling really ill and very tired all the time. I thought my life was basically over but I was sure it was the tablets that was causing it all and was linked to how it affected my digestive system, it was causing my gut to balloon which seemed to cause the heart issues. All heart scans were fine. I argued with my doctor who gave me metoprolol instead of bisoprolol. This improved things a bit but after a while I was feeling ill again. So I experimented with the combinations and found the solution quickly. It turned out that the combination of Rivaroxaban and Bisoprolol shut down my digestive system which caused the spikes in BP, pulse and arrhythmia . I am now on aspirin, metoprolol (low dose) and ramipril and it has been a miraculous recovery. No spikes at all, lots of energy and lots of hope and everything works again properly and it has even cured my psoriasis. The tablets were causing the problems they were designed to stop which was a little disappointing. I hope this story helps.

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Profile picture for glr702 @glr702

Hello,
I took propranolol 10mg 4 times a day for a week. Had horrible side effects, was switched to metoprolol succinate 25mg once a day for 2 weeks, felt a little better but still many side effects, so I was on them for about 3 weeks only. I tapered down and took the last dose 6 days ago. The first day was horrible, then a little better the second, same on the third. However, I’m still having palpitations, dizziness, head feeling weird, some tachycardia (somewhat less today), weakness. I’m much better than when I was on the medication, that’s for sure. I had almost all of the side effects I could get and even ended up dehydrated in Urgent Care, also got anxiety for the first time in my life which has been horrible. So, my main question is: am I any close to the end of this road? I don’t know if I’ll ever be able to feel like myself again. I was put on this for occasional hypertension and tachycardia, which I believe was caused by stress. I would appreciate it so much if someone could help me with their experience. Thank you so much

I’m listing all the side effects I had with these medications, sorry for the long post:
✔️Blurred vision
✔️chest pain or discomfort
✔️like electrical current in head
✔️tingling, chills like on arms, back and head
✔️confusion
✔️palpitations
✔️dizziness, or lightheadedness when getting up suddenly from a lying or sitting position
✔️hair loss
✔️dry mouth
✔️hot flashes/heat intolerance
✔️sweating
✔️unusual tiredness or weakness
✔️insomnia, nightmares
✔️soft stools
✔️difficult or labored breathing
✔️difficulty with speaking
✔️extreme tiredness or weakness
✔️fast, pounding, or racing heartbeat or pulse
halos around lights
✔️headache
✔️overbright appearance of lights
✔️lose weight
✔️seeing, hearing, or feeling things that are not there
✔️tightness in the chest
✔️tingling of the hands or feet
✔️troubled breathing
✔️continuing loss of appetite that got to the point when only could eat liquids
✔️continuing abdominal pain
✔️continuing nausea
dark urine
✔️difficulty with moving
fever
✔️general tiredness and weakness
✔️hoarseness
✔️increased frequency of urination
✔️muscle pain
✔️sore throat
✔️sores, ulcers, or white spots on the lips or in the mouth-white tongue
✔️unpleasant breath odor
✔️weakness
✔️anxiety

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I am getting off Metoprolol now. The nausea is doing me in - same with Carvedilol. I am also having sores in my mouth, weakness, muscle pain, loss of hair and difficulty with breathing. I need to find a beta blocker that does not cause nausea. That seems hard to do.

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Profile picture for gloaming @gloaming

Most of us have HR less than 75 when at rest, but the medical community seems to think that anything less than 100 BPM is considered within 'normal' range. There are others in the medical community, and I share their view, that anything higher than 90 BPM is a sign that something is going on. Personally, and it's just my opinion, and I have been a fit runner all my adult life (with resting HR of 38), when I awaken to a heart at 70BPM, I figure I'm in slow AF or I'm having PACs (premature atrial contractions). A recent Holter monitor confirmed the PACs. When my Samsung Galaxy watch shows HR of 85, I know I'm in AF. Above 120 BPM, I'm in flutter.
You are allowed up to 200 mg of metoprolol each day ON THE ADVICE AND UNDER CARE OF A QAULIFIED PHYSICIAN!! I just came off 150 mg when a second ablation seemed to have fixed me. Months earlier, a week after my first ablation, I went into tachycardia and was put on amiodarone. I had to cut the metoprolol the same day...cold turkey. Didn't phase me because the nasty and toxic amiodarone cured my arrhythmia...oops...STOPPED my arrhythmia. There is no real cure that we know of. My point is, metoprolol works, but some don't tolerate it well. More may actually be better. You want your HR lower than 100 consistently, and if you can get it less than 80, that's great.

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Thank you for the reply..I think a fast heartrate 90 to 95 may be normal for me..some people might just have a higher heartrate and some lower...as long as I stay asymptomatic..not going to increase the medication...my heart rate does go down to 76 to 78 at night..I just wish it was like that during the day

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