1. < Colorectal Cancer

Vectibix

Posted by davy80 @davy80, May 5, 2016

I am being treated for inoperable metastatic mesenteric cancer with the monoclonal antibody Vectibix. This is by iv infusion every two weeks. After 2nd session I have had many episodes of very low blood pressure(88/58) with extreme shortness of breath occurring when I do moderate activity. I've read that this is a side effect of Vectibix. Anyone else had similar experience and if so how did you deal with it?

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Ethan McConkey, Moderator | @ethanmcconkey | Jul 20, 2019

Hi @brenz, you may have noticed I moved your post to this existing discussion so you can see what others have said about this medication. Simply click VIEW & REPLY in your email notification to get to your post.

What have your doctors told you and your husband about this medication?

REPLY
Kanaaz Pereira, Connect Moderator | @kanaazpereira | Jul 23, 2019

Hi @brenz,

Here’s some information from Mayo Clinic on Vectibix (panitumumab): https://www.mayoclinic.org/drugs-supplements/panitumumab-intravenous-route/description/drg-20069235

I’m also tagging @rayleemorris, who was diagnosed with colorectal cancer in 2010, and has shared a few thoughts about Vectibis.

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lah | @lah | Nov 10, 2019
In reply to @brenz "Has anyone taken Vectibix ? If so what were your side effects? Did it work? My..." + (show)
@brenz

Has anyone taken Vectibix ? If so what were your side effects? Did it work? My husband will be starting it with Xeloda soon and looking for info on Vectibix. He has been on Xeloda so we know what to expect. Thank you

Jump to this post

My husband took vectibix . His side effects were the rash and acne on his face. He said it felt like his face was burning. Looked like he had a bad sunburn.He also had some mouth sores that made it hard to eat and he pretty much stopped eating. He lost a bunch of weight, so pack on the pounds if you can. After a couple bags of fluid, and dr stopped the infusion to give him a break. Unfortunately it did not cure his cancer .colon (cancer metastasized to his lungs.) Prayers and best of luck!

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1 reply
mscoyote | @mscoyote | Nov 12, 2019
In reply to @lah "My husband took vectibix . His side effects were the rash and acne on his face...." + (show)
@lah

My husband took vectibix . His side effects were the rash and acne on his face. He said it felt like his face was burning. Looked like he had a bad sunburn.He also had some mouth sores that made it hard to eat and he pretty much stopped eating. He lost a bunch of weight, so pack on the pounds if you can. After a couple bags of fluid, and dr stopped the infusion to give him a break. Unfortunately it did not cure his cancer .colon (cancer metastasized to his lungs.) Prayers and best of luck!

Jump to this post

Hi @lah, our story is very similar to yours, though no mouth sores or weight loss as yet, but certainly metasmases to lungs and liver. Our understanding is that vectibix (panitumumab) is only supposed to stop the tumours from growing. No hope of cure. Also prayers.

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