VDT rate and Cancer?

Posted by kinsan @kinsan, Jul 5, 2022

Hello everyone! Is there a rule of thumb regarding VDT of a lung nodule and the likelihood of that nodule being cancer?

If someone has a nodule that doubles in size in a matter of two weeks, does that present like acute inflammation, or a fast moving small cell cancer? The patient has been symptomatic for an acute illness that has yet to be diagnosed, and a lung nodule was discovered incidentally while evaluating the colon via CT, and it was imaged two more times in a span of two weeks and doubled in size between scan one and scan three.

A fourth scan is scheduled for next week, and if is still growing, plans are to biopsy the nodule. Thanks for your insights!

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@kinsan, welcome. I'm sure you've scoured the Internet already about volume doubling time (VDT). This article explains:

"The volume doubling time (VDT) is an important volumetric parameter primarily used in lung cancer screening and follow-up by chest CT. Volume doubling time is defined as the time required for a growing nodule to double its volume. A longer VDT suggests a more benign course, whilst a short VDT is indicative of a more aggressive lesion with higher histological grade." Read more here:
- Volume doubling time https://radiopaedia.org/articles/volume-doubling-time

Lung nodules are very common. I'm relieved to hear that the patient is being closely monitored and will get a biopsy. Is a gastric disorder suspected and hence the CT of the colon?

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