Tymlos and Liver Enzymes.

Posted by imay @imay, Dec 24, 2023

I have been using Tymlos for 5 month and two out of the three standard liver enzymes have increased significantly, both AST and Alkaline Phosphatase. My liver number was tested after 2 months and the elevation was slight but is is higher now. At that time I was told that some people get a jump in ALP from taking Tymlos. Has anyone had the problem? I wonder if I will be able to continue Tymlos, maybe at a reduced dose.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

@imay How interesting that you posted this today. I just got my lab results back before my next Evenity injections that take place on Dec. 26. Like you, my ALK phosphotase went up. There are reasons other than liver enzymes why these would increase such as changes in the bone. I plan to ask my prescribing endocrinologist about this. Are you going to ask your doctor too?

REPLY
@naturegirl5

@imay How interesting that you posted this today. I just got my lab results back before my next Evenity injections that take place on Dec. 26. Like you, my ALK phosphotase went up. There are reasons other than liver enzymes why these would increase such as changes in the bone. I plan to ask my prescribing endocrinologist about this. Are you going to ask your doctor too?

Jump to this post

Yes. I see my primary care doctor on the 3rd but I already sent a message through the portal to the PA who runs the bone clinic. She is the one who mentioned it. I have been reading up on it and it seems that ALK phosphatase can be a marker for bone building or breakdown. ALT is more specific to the liver, and that was normal, but AST can also reflect damage to the muscles, heart or liver. Mine was elevated too. Anyway, I think the reason they rechecked my liver enzymes after 2 months was because of a possible increase in ALK phosphatase, I just don't know what it means.

REPLY
Please sign in or register to post a reply.