Tylenol eight hour arthritis pills for joint pain?

Posted by lindaadel @lindaadel, Sep 28, 2024

I was wondering if it pays to give Tylenol eight hour pain relief pills a try for my joint pain? every once in a while my rheumatologist asks me if I have ever tried Tylenol which I never did. I am not doing well on any of the pills that I’ve tried so far all they do is give me way too many side effects which are not great!!! any information would be helpful!!!

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twistedwillow | @twistedwillow | Dec 21, 2025

Quite right. I didn’t clarify extended release. Regular Tylenol can be split and are often marked. There are many contraindications to Tylenol and of course the dose should be checked with your dr. My main point is that healthcare is expensive and for those with limited income and no insurance knowing that generic is acceptable may help.

Mike | @dadcue | Dec 21, 2025

In reply to @twistedwillow "Quite right. I didn’t clarify extended release. Regular Tylenol can be split and are often marked...." + (show)

@twistedwillow

I absolutely agree that generics are acceptable in most cases and for most medications. Generic medications do save a lot of money.

There is no "brand-name" for the prednisone we take so all prednisone tablets are generic. The brand-name reference drug for prednisone is Deltasone, which has been discontinued in the United States.

The only remaining brand-name version of prednisone currently on the market in the U.S. is Rayos, which is a delayed-release tablet. That formulation of Prednisone costs a fortune for some reason in the U.S. Most insurance companies won't pay for Rayos because it is said that "it isn't medically necessary."

I have always wanted to try Rayos to see if I could go an entire night without pain. Thankfully ... I don't take Prednisone anymore. I have been on Actemra for 7 years and off Prednisone for 5 years.

Actemra costs a fortune too. However, I don't have anywhere near the hospitalizations and emergency room visits as I did when I was on Prednisone. I have also stopped almost 10 other medications which were primarily treating Prednisone side effects. Having reduced my overall medication burden by stopping ten other drugs used to manage prednisone side effects is a positive development for my overall health and well-being.

I take a small dose of generic acetaminophen almost every night before bedtime for "residual pain." Anyone who can take acetaminophen for pain instead of Prednisone is on the right track in my opinion.