Treatment for amyloidosis and multiple myeloma

I am currently on Velcade ad Daramumtab infusion to lower my light chains after Dara did not work alone. My first lab was yesterday and instead of lowering, my light chains had gone up 3/4 of a point. We're going to check agan in two weeks then "go from there". Is there anyone out there who has had a problem similar to this? If so, please respond as I''m very concerned. Becky Outlaw