Topical creams and lotions for Small Fiber Neuropathy

My Neurology NP prescribed a topical cream made up of gabapentin and amitriptyline for small fiber neuropathy. Does anyone have experience with a topical with either of these ingredients? She typically prescribes it with lidocaine, but I chose not to have it included because I don’t like the feeling of numbness and lidocaine doesn’t work well for me due to an underlying condition.

I tried a special compounded cream prescribed by my neurologist. It did have lidocaine and a bunch of other stuff. Was expensive and did nothing. The neurologist did say he had not seen any real success with the various creams he had prescribed, including those with Gabapentin

Thanks for sharing your experience. That’s kind of what I thought… I’ve tried topical diclofenac for pain and got no response. And I’ve used topical CBD for my neuropathy, which helps, but it’s unclear to me if it’s the CBD or just the fact I’m putting something moisturizing on.

I decided to go ahead and order it, so I guess I’ll see how it goes and can report back. Thanks again.

I have neuropathy in numerous areas, all pelvic, buttocks and upper front and back of thigh. For years…
Still working through potential causes- just finally diagnosed with ischial bursitis, both sides; having lower spine nerve ablation on 8/1; and seeing orthopedist 7/31 to go over results of left hip mri.
I am hoping that something can be found/fixed/or at least properly treated.
In the meantime, I am using diclofenac RX patches, pricey; look up good RX for best price, they work much better and longer than the gel. Also, using a tens unit when it gets really obnoxious. Another thing I have found, is a cream that is not RX, and can find online. Sombra. Has a bit of a burning sensation at first, but then just turns to warm. It feels so good, no drugs and can last for 3-4 hours. Wash your hands well after using!!!
Hope you find a way to cope! 🤞

Thanks! Wishing you luck with your follow-up and hope you’re able to find some answers and guidance. At the very least, for the bursitis pain, if it doesn’t calm down with anti-inflammatories, hopefully PT would help with that. I had/have this too, and it thankfully improved with PT, but wow bursitis pain can really burn.

@eno, @ch47, @day333 and all...I've tried everything from Voltarin cream which does give me some relief to ease things enough to relax my legs and feet some; tried magnesium cream that is helpful, but not enough; and multiple other creams and oils which did not much but helped my dry skin some...didn't resolve the issues.
Then, I was prescribed a steroid cream to use sparingly on my arms for the Sarcoid rash, for 2 weeks at a time since it begins to cause side effects such as thin skin and such. I used it one night on my feet and legs during a serious attack of burning and needles sticking, heat, etc. It was great! I now use that cream when I have a worse than normal attack and I'm thrilled with the results. It also resolved the rash on my legs that caused bumps so big, red, and irritating. They are gone. They may have been Sarcoid or vasculitis, don't know, don't care. It worked and resolved the issue. Now, I use CBD lotion several nights weekly on my arms and legs. I get it from Winged Wellness online. It has been very helpful in keeping legs, feet, arms, hands, shoulders, and neck free of rash, with fewer flares with pins and burning and pain. I'm very pleased.

I think I have a plan now that works well for me. Hopefully, some of my information will help you with this at times horrible discomfort. I have RLS and take Requip every evening. By taking it earlier than bedtime, it is helping me a lot with the RLS, and these creams added are making a huge difference in my nights.

Blessings as you walk this journey...Elizabeth

Thank you…could you share the name of the steroid cream? My doctors are so willing to try anything, unless harmful, of course. We have been working together so long-they know I use meds as rx’d.
It would be wonderful if the steroids would help-is there any concern about too much steroid use?

@ch47, and all...Of course. It's prescription: Triamcinolone Acetonide Cream USP, 0.1%./
I use it in an area occasionally, or as needed for no more than 2 weeks at a time, with 2 weeks off. This keeps me from having any steroid reactions. It's a wonderful way to get the steroid benefits without ingesting them, which I've done for decades with many ill effects. I have a steroid love/hate relationship as they have saved my life and helped so much while causing havoc in other areas.

Wishing you well with this regimen...Elizabeth

You all are a wonderful support system…

Thank you!
Will see what they say…