Titration with Tymlos?

Posted by pgn @pgn, Aug 30, 2024

I’ve recently been prescribed 80mg doses of Tymlos. I’ve been reading and have had a few bad reactions to other drugs (I’ve had Lupus since I was 62 and am now 73 ). After reading on this site I’ve recognized that some people have “built up” slowly to a full dose. They’ve started with a lower dose by clicks in the dosing pen. I asked my rheumatologist about trying this and she indicated that the manufacture of Tim Los indicated, but that wasn’t possible to do. Does anyone have any comments on this? Has anyone tried using the dosing pen in that manner? I think I’d feel more comfortable, easing onto the medication rather than taking the full dose. Thanks for your thoughts.

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Profile picture for gently @gently

hi lp30, no dots. You have to listen for clicks as you turn the dial. Each click is 10mcg. I hope this works for you. Some refrigerate the pen if titrating because the pen will last longer, I haven't taken Tymlos, but am taking Forteo--another good choice.

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@gently Thank you I will give it a try!

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Profile picture for harryboy7 @harryboy7

I have read a lot about Tymlos. Several people on this support group talked about one click, 2 clicks....and so on. Talking about doing less of the drug and then working up to the ordered dose.
I really like this idea. I am a retired hospital RN. We did this often, especially with some of the IV drugs we did.
I just got my first shipment of Tmylos. I have not started yet. My dose is 80mcg. It is set for that dose. I talked to Tymlos on the phone. They said you can't do that. I am curious about the people who do this.
Also they say the injection spot is only on the belly. There are several SQ injections site. Tymlos says only the belly for the shots. If we are giving daily shots on the belly...My belly will be a wreck. Feed back? Thanks Robin

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They want to sell their drug that is why they want you to use more of it. Just like Ozempic. Doctors are prescribing too high a dose and people lose weight so fast along with muscle. Micro dose is the key with Ozempic. Peptides are not a bad thing. I would ask a doctor you trust before you start.

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Profile picture for harryboy7 @harryboy7

That is what I am doing also. I too am titrating. I am now doing 6 clicks. My back hurts more, and I feel nauseous since doing 6 clicks. I probably will go back to 5 clicks'
I am curious where you got the information about Tymlos and testing with other amounts. I thought I read everything, and even talked with Tymlos. Nevertheless, I still would titrate. It just makes more sense. There has been a lot of talk regarding injection sites, Everything points to the stomach only. There are more SQ injections sites. Not just the belly, I am not sure way that is. Maybe you might have some information. Thanks for your information and your experience.

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@harryboy7 what about the thigh, which I used for a blood-thinner after surgery…?

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Profile picture for dvargo @dvargo

They want to sell their drug that is why they want you to use more of it. Just like Ozempic. Doctors are prescribing too high a dose and people lose weight so fast along with muscle. Micro dose is the key with Ozempic. Peptides are not a bad thing. I would ask a doctor you trust before you start.

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@dvargo I’m confused. How is Tymlos like Ozempic other than being a drug? Is there indication out there that you can gain the bone in a lesser dose?

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Profile picture for lp30 @lp30

@dvargo I’m confused. How is Tymlos like Ozempic other than being a drug? Is there indication out there that you can gain the bone in a lesser dose?

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@lp30 I am talking about dosage. How doctors over dose the meds. Ozempic is a life saver if you micro dose it. You would have to talk to your doctor about slow walking the Tymlos. Have you looked up what percentage Tymlos prevents fracture? Are there studies on how much bone you gain on Tymlos? We have to do our own research then decide.

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Profile picture for harryboy7 @harryboy7

I have read a lot about Tymlos. Several people on this support group talked about one click, 2 clicks....and so on. Talking about doing less of the drug and then working up to the ordered dose.
I really like this idea. I am a retired hospital RN. We did this often, especially with some of the IV drugs we did.
I just got my first shipment of Tmylos. I have not started yet. My dose is 80mcg. It is set for that dose. I talked to Tymlos on the phone. They said you can't do that. I am curious about the people who do this.
Also they say the injection spot is only on the belly. There are several SQ injections site. Tymlos says only the belly for the shots. If we are giving daily shots on the belly...My belly will be a wreck. Feed back? Thanks Robin

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I'm 70, female, and found out about my osteoporosis by fracturing my spine. I have been on Tymlos a full year. Started at the full dose; I want it to work! I don't ever want pain like that spine fracture again.

DEXA after 7 months showed gain of a full pint in the spine, from -3.1 to -2.1 (that is just osteopenia now). Never going back to osteoporosis again.

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Can someone tell me what the two black arrows mean when you click on the Tymlos pen? Is it a half dose?

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Profile picture for rileyf @rileyf

Can someone tell me what the two black arrows mean when you click on the Tymlos pen? Is it a half dose?

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@rileyf If your question is "when you see 2 black arrows is this 1/2 dose." Each click is 10 mcg. To see the 2 directional arrows in the window together, you would have had to had 4 clicks which is 40 mcg. The injection is programed at 8 clicks or 80 mcg, so the answer would be yes, the 2 arrows would be 40 mcg or 4 clicks.

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Profile picture for zygote @zygote

@rileyf If your question is "when you see 2 black arrows is this 1/2 dose." Each click is 10 mcg. To see the 2 directional arrows in the window together, you would have had to had 4 clicks which is 40 mcg. The injection is programed at 8 clicks or 80 mcg, so the answer would be yes, the 2 arrows would be 40 mcg or 4 clicks.

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@zygote Thank you so much for clarifying!!

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Profile picture for alicevondall @alicevondall

Because of extreme exhaustion I asked my Dr. if I could scale back on the dosage. My pen says 80 also-but she said it was impossible to do that, so I appreciate your information, Windyshores. Of course, after complaining to the Dr. within a few days my exhaustion did get better. So a big thank you for the people on here that told me to hold on-that it would get better. She did tell me to go off the Tymlos for 2-3 weeks and see if that made a difference. She also said tiredness was not a side effect of Tymlos, but I see other people on here have experienced extreme tiredness too. I am almost a month in, so I did not want to do that and go through the side effects all over again. Although I am still tired the extreme has disappeared, and walking does help in the morning.

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@alicevondall I have exhaustion every day. Problem is, I don't know if it is because of living with spouse with Dementia! I have a caregiver 5 days a week, so that helps. I think I will ask my bone doc about reducing dose since I only weigh 110 and am 5'2"

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