Tips on minimising withdrawal symptoms from Effexor (aka Venlafaxine)

Posted by richyrich @richyrich, Nov 2, 2016

I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you

Liked by Bek, LynneB, kelly76, echams1 ... see all

@dianrib

Just 5 days off meds ? Thats great When I just cut down I feel real bad

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@dianrib….didn't you say you felt worse @ your current rate of cutting your dosage? Maybe you are cutting back too much, too quickly. You must listen to your body. Everyone is different. I've only been taking it for 2 years. Tommorrow will be 7 days. Its been trial and error. Anything to avoid the brain in the roller coaster for me. Let me know how you are doing! I'm here for you!!!

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@parus

All I can say is my withdrawal from EFFEXOR over 8 years ago is NOT something I would want to experience again. I can say I am more at peace with myself and others without this DRUG. Withdrawal from these type of DRUGS can be lethal w/o proper supervision. Sad that professionals are NOT better educated or just don't care…

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Did anybody tell you your body would become addicted?! Not me. I feel a class action lawsuit is inevitable!

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@brightwings

I am posting this so any that are interested can participate.
The NEXT SACRED CEREMONY in southern Missouri is scheduled for June 23, it starts at 9 am. Don't be late unless you have long distances to travel. I like to get there the evening before. The folks who attend are so wonderful, interesting, and healing folks.
The church is called New Haven Native American Church, Ava, Missouri. Google it.
There is a small chapel to stay in overnight if you choose. Lots of others will be there. We are up to about 70 or so folks every ceremony.
The location of the ceremony is 14 miles west of Ava, Missouri, straight west of Ava on highway 14. When you cross the Bryant River, you are there. Turn right at first driveway after river.
This ceremony is called Be Still in The Moment. Or Peyote. These sacred medicines have allowed me to get off the antidepressants. AND Ayawaska ended my depression.
So any questions, ask away. Smiling at you, Hope to see you there. Bright Wings

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I just wanted to let you know I purchased CBD oil today. I used it twice already. 3 drops under my tongue. I was vomiting last night and extreme nausea this morning. I haven't experienced it after taking it. Mind you, this could just be a fluke or an initial placebo effect. Can you tell me your experience as far as how quickly you felt relief ? Curious if it's pretty quickly after dosing or does it need awhile to get into my system quickly. Thank you! You've been really helpful. Truly appreciate it!

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@parus

All I can say is my withdrawal from EFFEXOR over 8 years ago is NOT something I would want to experience again. I can say I am more at peace with myself and others without this DRUG. Withdrawal from these type of DRUGS can be lethal w/o proper supervision. Sad that professionals are NOT better educated or just don't care…

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The medical profession covers themselves with all the printed warnings that come with each new prescription or refill. 🙁

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@dianrib

Just 5 days off meds ? Thats great When I just cut down I feel real bad

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Hi. Wanted to share my thoughts as well. Weaning off to quickly can give you horrible side effects. Definitely trial and error. I'm doing this now and it stinks. I just reduced again from 150mg to 75mg and it hit me to hard. I think (but don't know yet) in my case I need to alternate days. 150 mg then next day 75mg to slow the side effects a bit. You may have to increase a bit to stop all the side effects again and go slower. I think in my case I probably need to go from the 150mg to 125mg for example instead of going straight to just the 75mg a day. Does thst make sense?

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@dianrib

Just 5 days off meds ? Thats great When I just cut down I feel real bad

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@dianrib ….Let's tag her on this too ok?
THANKS. She's having g a rough time & I believe dealing w tablets like me.

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@dianrib

Just 5 days off meds ? Thats great When I just cut down I feel real bad

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@amelia42 …I tagged @ dianrib on this. Just figuring out the"@" thing!

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@medfree17

So I ended up making the decision to come of the Venafalaxine! Best decision ever! I have been constantly taking my CBD oil and I have never felt better! I have not taking any meds for 2 whole days and this is the first time in over a year! I am feeling fantastic right now because of it! I highly recommend trying! To everyone struggling stay strong and don’t let anxiety get the best of you. Be open about it even if people don’t understand. It has been the best form of therapy for me plus the CBD oil ❤️

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@brightwings….thank you so much! I always read your posts. You bring so much to the group. BTW…..I cannot find your post about the gathering in MS. I am intrigued to put it mildly. Was looking @ flights, closest to the gathering, also time of flights since I have so much tailbone pain, sacroiliac problems w numbness & pain down my leg & knee. Thanks!

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@brightwings

I am posting this so any that are interested can participate.
The NEXT SACRED CEREMONY in southern Missouri is scheduled for June 23, it starts at 9 am. Don't be late unless you have long distances to travel. I like to get there the evening before. The folks who attend are so wonderful, interesting, and healing folks.
The church is called New Haven Native American Church, Ava, Missouri. Google it.
There is a small chapel to stay in overnight if you choose. Lots of others will be there. We are up to about 70 or so folks every ceremony.
The location of the ceremony is 14 miles west of Ava, Missouri, straight west of Ava on highway 14. When you cross the Bryant River, you are there. Turn right at first driveway after river.
This ceremony is called Be Still in The Moment. Or Peyote. These sacred medicines have allowed me to get off the antidepressants. AND Ayawaska ended my depression.
So any questions, ask away. Smiling at you, Hope to see you there. Bright Wings

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CBD? What does this stand for?

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Hi. I’m new here and happy to have found the group. I have anxiety and depression. Over the years I have taken various medications and have switched because they aren’t effective, stop working for me, or the side effects are awful. I have been on 150 mg of Effexor XR for years now. I ran out this week so haven’t been taking it for several days. I feel awful! Brain zaps, lightheaded, nauseous, diarrhea, sleeping a lot, cold/hot, vivid dreams…. I finally got my refill and resumed the medication this morning.

The brain zaps people mentioned coming off of Effexor caught my attention. Was anyone experiencing those while on it?? I have, along with my pupils being different sizes. A neurologist said I have migraines without headache and has me on another med to combat that. Now I’m wondering if all along it hasn’t been the Effexor, and if I should reach out to my psychiatrist about weaning off of it along with the second medication.

Meanwhile, I’m weathering the mini withdrawal and getting back on. No fun at all!!!

Thank you for your thoughts and input.

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Thank you everyone for your input on withdrawing from Effexor. I was put on Effexor 20 years ago for traumatic brain injury headaches and depression. I wanted to try life without Effexor, so my doc prescribed the 150mgs in smaller doses so that I could taper. My insurance wouldn’t cover the smaller doses and calls to my doc have gone unanswered. So, I am out of Effexor and on day 2 of forced cold turkey. Going to try a little exercise this morning as recommended by coloradogirl… I won’t begin to tell you guys how I feel – sounds like you’ve all been there. #tryingtobebrave

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@bamagirl10

Thank you everyone for your input on withdrawing from Effexor. I was put on Effexor 20 years ago for traumatic brain injury headaches and depression. I wanted to try life without Effexor, so my doc prescribed the 150mgs in smaller doses so that I could taper. My insurance wouldn’t cover the smaller doses and calls to my doc have gone unanswered. So, I am out of Effexor and on day 2 of forced cold turkey. Going to try a little exercise this morning as recommended by coloradogirl… I won’t begin to tell you guys how I feel – sounds like you’ve all been there. #tryingtobebrave

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Try weaning off slowly Good luck Its a struggle for most

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@gb1988

I’m weaning off of Venlafaxine after only 2 mos of taking it. It caused violent personality changes in me – which is atypical behavior. As in I was yelling at my amazing, gentle boyfriend / soon-to-be fiancé over NOTHING and felt like I could just hit him. HORRIBLE. I felt BIPOLAR. Thank goodness he went through a personality change, too, years before we met when he was trying to find the right meds for his anxiety, so he understood, otherwise I guarantee our almost 2-year relationship would have ended that night. I was sobbing uncontrollably, angry…gosh it was horrible. The medication was supposed to make me feel better for goodness sakes, not turn me into a worse version of myself!

I initially went on it after Sertraline caused only one of my pupils to dilate, and at the advice of the ER pharmacist, I immediately stopped taking the Sertraline, as this can be indicative of a rare but serious side effect. I had wanted help with GAD and bad PMDD, no depression outside of my menstrual cycle. (Can’t take birth control or any other type of hormonal therapy, so I wanted to find alternative options for helping the PMDD.)

My doctor then put me on 37.5 mg of Venlafaxine and as I said now I’m weaning off of it due to the crazy personality change after 2 mos. I’m done trying meds after this; for my somewhat milder symptoms, it’s not worth the side effects.

It’s day 5 of weaning off, I took 1/2 pill per doctor’s advice for the first 3 nights, didn’t take it last night (night 4) and now day 5 I feel like I’m going to throw up. I have the jitters too.

However, I’m kicking myself because I had 4 cups of full caff coffee this morning about 4 hours ago (stupid!), and due to my extreme sensitivity anyway with caffeine, that made my nausea even worse. I feel like I’m about to burst into tears, too, because of not feeling well and the emotional changes of getting off the meds. If it’s this bad after only 2 mos taking 37.5 mg, I can’t imagine how terrible it would be for those on a large dose for years.

My body is HYPER sensitive to all things caffeine, alcohol, med related. My doctor even said she wouldn’t help me further with picking a 3rd medication to try, as my body indicates its more sensitive than others’. She referred me to a psychiatrist as they are “more familiar” with medications for anxiety, etc., and would do a better job picking a medication for me. But since the GAD/PMDD are mostly managable, I’m done with the experiment of trying medication to help – I gave it a good go.

I’m a 5’7”, 120 lbs, (29 yrs old), and my doctor said that having a smaller frame and lower dose should mean I won’t have as bad of withdrawal symptoms. Compared to others, I know she’s right, but as I’m typing this I’m fighting the urge to go try and throw up. AWFUL MEDICATION TO WEAN OFF OF! Do it gradually. Do not stop cold turkey – I am just so glad I was on a low dose for a short time. Doctor said it should only take 7 days for me to wean off since my dose was so small. Thank goodness it’s Saturday, so I can lie on the couch all day and I have tomorrow, too, to help me HOPEFULLY feel normal again by work Monday.

Tips: 1. Stay AWAY from caffeine 2. GRADUAL weaning off 3. Don’t give up! I’m also fighting the urge to take a half a pill today, but I don’t want to do that because that’ll set me back. I’m following my doctor’s weaning-off plan and in her words, there’s not much I can do to wean off since my dose was so small already. She said just to cut the pill in half and take the half pill for 3-4 nights.

Folks who are on very high doses, oh I feel for you. Blessings for strength to keep up the weaning-off path and not to relapse into taking it again.

I was petrified to wean off because “Doctor Internet” had so many posts about Venlafaxine being the worst medication of its kind you can possibly try to wean off of. Doctor Internet was right. It sucks, and I was only on 37.5 mg for 2 mos.

If possible, maybe ask your doctor about going on a different medication if you’re trying to decide between starting Venlafaxine (which is the generic brand of Effexor) and a different medication.

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@gb1988 based on your symptoms, I suggest that you obtain pharmacogenomics testing to see if you properly metabolize medications based on your genetics.

In a nutshell, based on your genes, you may be too slowly or too quickly metabolizing medications. Also, and this is very important, many medications inhibit (slow down) or induce (speed up) these genes as well. This is what is meant by "drug-drug interaction."

I was sick for 12 years, eventually took myself to Mayo Clinic, asked them to evaluate me for drug hypersensitivity, and we figured out that I don't properly-metabolize most drugs because of genetic polymorphisms (mutations). Many of these polymorphisms lie within the cytochrome p450 liver enzyme system.

If you can't get this done at Mayo, there are several mail order companies that do it, as well. I have used OneOme (owned by Mayo). You need to find a company that is certified by the state you live in to do this kind of testing.

Google "pharmacogenomics testing" and "PGx" testing.

You'll need to have your doctor contact the PGx testing lab to initiate the process.

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@parus

All I can say is my withdrawal from EFFEXOR over 8 years ago is NOT something I would want to experience again. I can say I am more at peace with myself and others without this DRUG. Withdrawal from these type of DRUGS can be lethal w/o proper supervision. Sad that professionals are NOT better educated or just don't care…

Jump to this post

Few bother to read the inserts WE count on our doctors to do whats right and warn us about serious side effects !!!

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@brightwings

I am posting this so any that are interested can participate.
The NEXT SACRED CEREMONY in southern Missouri is scheduled for June 23, it starts at 9 am. Don't be late unless you have long distances to travel. I like to get there the evening before. The folks who attend are so wonderful, interesting, and healing folks.
The church is called New Haven Native American Church, Ava, Missouri. Google it.
There is a small chapel to stay in overnight if you choose. Lots of others will be there. We are up to about 70 or so folks every ceremony.
The location of the ceremony is 14 miles west of Ava, Missouri, straight west of Ava on highway 14. When you cross the Bryant River, you are there. Turn right at first driveway after river.
This ceremony is called Be Still in The Moment. Or Peyote. These sacred medicines have allowed me to get off the antidepressants. AND Ayawaska ended my depression.
So any questions, ask away. Smiling at you, Hope to see you there. Bright Wings

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I TAKE IT for a short time No vomiting for me. CBD is New to me

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