Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)

Posted by richyrich @richyrich, Nov 2, 2016

I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you

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I'm in America, but unfortunately I can't go back to my original dose because it was so high, they said it would be dangerous for me.

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Profile picture for dewi-s @dewisoraya

Hi nonnie!

Wow that's a short amount of time! It could be withdrawal symptoms as you're body's trying to adjust to being without it.

When experiencing these symptoms, it could be a sign from your body that you may have tapered too quickly. I've read that in order to minimise these symptoms, it's suggested to taper more slowly and in smaller steps. That way your body has more time to adjust to it.

Right now I'm experiencing headaches (with a buzzing drum in my head almost?) and flu like symptoms. I am tapering Venlafaxine as well. Reading more and more about it, right now I'm preeettty sure these symptoms are withdrawal symptoms.
Also thank you @keppraeffect for making me think that it is probably good to taper down more slowly!

Can you talk about these symptoms with your doctor? I hope they can help you at least lessen the symptoms since you're already off the venlafaxine.

All the best!

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My goodness~ your taper is by far the quickest I have read about.
I am 63 - been on anti depressants for about 30 years. Initially started after a difficult child birth, a big company move shortly after. . I started off with Prozac - it saved me. I had developed agoraphobia . I thought I must have a brain tumor! Not much was written about it back in the day. But I was handed the book (by a stranger in a library ) (“Peace from nervous suffering” written by Claire Weeks. This was a Godsend. It was like it was written personally for me! I was not going crazy - !!! I have a chance. Eventually Prozac stopped working and went to a few different ones after that. Since 2021 I have been tapering off of Effexor. It stopped working for me once I was in full menopause. (2 years ago) I had no joy. I’ve been slowly eliminating it out of my system over a year and a half. 225mg- 150 (hardest taper..struggled..my darkest time). I felt like I was dying. Darkest thoughts. Paralyzing fear. With all the strength I had, I put my self into a 36 day TMS regiment. Just getting out of bed everyday and showing up an huge achievement. I started to feeling a positive shift after my 17th appt. - I was showering every day and running occasional errands. For a full month after - I felt normal. Energized, calm, participating in life, patient, engaging…best feeling in life. Is this what life is suppose to be like? After 40 days- the magic left me. I was devastated. One month passed and I decided to put my self back in to TMS but for only 3 days a week. I just started- so I will keep you posted. I am now on 75+37 1/2 mg …feel nauseous and have a lot of brushing sounds in my head. .. . I will eventually go to 75mg —anxiety is so debilitating to me.
They are not recommending Xanax..because the new studies are they are linked now to Alzheimer’s (besides being addictive) My pcp won’t prescribe them anymore. Paxil is out of the question because like Effexor…it’s another drug that’s a struggle to get off of. If I miss just 1 dose of Effexor, I can’t even walk without holding on to a wall! I can’t turn my head with out electrical shocks. Some shocks are so explosive and loud that it’s frightening. It’s like someone shutting off the power grid for a whole skyscraper. . I often feel like In have the flu. The sweeping and zaps are ridiculous. Big Pharma took their first Effexor pill off the market for a reason. I’ll never understand why this XR is even on the market. To me it’s a poison. I’ve been in anti-depressants for at least 30 years.
Anytime I mentioned i was feeling blue or having anxiety - my pcp’s just assumed my meds stopped working and changed them. It’s very frustrating.
Now I am experiencing restless leg/body syndrome- my body just jolts off the bed while trying to sleep. I am for medication if it works and has little side effects. Effexor is the devil. I’m sorry to all of you in this struggle. I will keep you in my thoughts. I’m rooting for all- N

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Profile picture for linxy @linxy

I went off Venlafaxine 4 weeks ago after being on it for several years. I tapered down from 225 to 75 myself, it was really ok. But i couldn't get down to 37.5 without getting brain zaps, nausea, headaches, insomnia, trembling, anxiety and all the rest. I went to see a psychiatrist who booked me into hospital for a couple of days to help me get off and to monitor me. For the first 2 days he put me on 37.5, then and from day 3 nothing. From day 1 though he put me on Urbanol that helped with anxiety, Aropax SR 25 mg, pain meds and nausea meds as necessary, Biotrazadone 100mg at night, Disipal that helped with the brainzaps and shaking and Inderal. Using those meds really helped a lot, i only experienced slight brain zaps, a little bit of nausea, diarrhea and vertigo, nothing as severe as when i tried to go of Venlafaxine by myself. Im off it now and adter a month i only get slight brain zaps occasionally, feeling a little weak and tired but nothing too bad. I could stop using Disipal, Inderal, pain and nausea meds.

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May I ask what you replaced it with ?

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Profile picture for tammy1016 @tammy1016

May I ask what you replaced it with ?

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Hi there. I am now on Aropax and Azor. I hope it helps.

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Profile picture for nananancy @nananancy

My goodness~ your taper is by far the quickest I have read about.
I am 63 - been on anti depressants for about 30 years. Initially started after a difficult child birth, a big company move shortly after. . I started off with Prozac - it saved me. I had developed agoraphobia . I thought I must have a brain tumor! Not much was written about it back in the day. But I was handed the book (by a stranger in a library ) (“Peace from nervous suffering” written by Claire Weeks. This was a Godsend. It was like it was written personally for me! I was not going crazy - !!! I have a chance. Eventually Prozac stopped working and went to a few different ones after that. Since 2021 I have been tapering off of Effexor. It stopped working for me once I was in full menopause. (2 years ago) I had no joy. I’ve been slowly eliminating it out of my system over a year and a half. 225mg- 150 (hardest taper..struggled..my darkest time). I felt like I was dying. Darkest thoughts. Paralyzing fear. With all the strength I had, I put my self into a 36 day TMS regiment. Just getting out of bed everyday and showing up an huge achievement. I started to feeling a positive shift after my 17th appt. - I was showering every day and running occasional errands. For a full month after - I felt normal. Energized, calm, participating in life, patient, engaging…best feeling in life. Is this what life is suppose to be like? After 40 days- the magic left me. I was devastated. One month passed and I decided to put my self back in to TMS but for only 3 days a week. I just started- so I will keep you posted. I am now on 75+37 1/2 mg …feel nauseous and have a lot of brushing sounds in my head. .. . I will eventually go to 75mg —anxiety is so debilitating to me.
They are not recommending Xanax..because the new studies are they are linked now to Alzheimer’s (besides being addictive) My pcp won’t prescribe them anymore. Paxil is out of the question because like Effexor…it’s another drug that’s a struggle to get off of. If I miss just 1 dose of Effexor, I can’t even walk without holding on to a wall! I can’t turn my head with out electrical shocks. Some shocks are so explosive and loud that it’s frightening. It’s like someone shutting off the power grid for a whole skyscraper. . I often feel like In have the flu. The sweeping and zaps are ridiculous. Big Pharma took their first Effexor pill off the market for a reason. I’ll never understand why this XR is even on the market. To me it’s a poison. I’ve been in anti-depressants for at least 30 years.
Anytime I mentioned i was feeling blue or having anxiety - my pcp’s just assumed my meds stopped working and changed them. It’s very frustrating.
Now I am experiencing restless leg/body syndrome- my body just jolts off the bed while trying to sleep. I am for medication if it works and has little side effects. Effexor is the devil. I’m sorry to all of you in this struggle. I will keep you in my thoughts. I’m rooting for all- N

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Most current study shows benzodiazepines are not linked to Alzheimer’s.

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I have been taking Effexor for 4 years. I am now at my lowest 37.5. I had to cold turkey stop on all medication’s for a surgery. I’m on day three Without it and these are the symptoms I’m experiencing. Anxiety,low energy,depression. I feel like I’m about to cry, but I don’t quite do it. My head is about to explode The brains zaps are terrible. Just getting out of bed is exhausting. My surgeries in two days after that, I’m hoping I could come back on it because I am miserable, irritable. Because I’m getting surgery, I can’t take anything else to help. Just been resting And avoiding people so I don’t snap at anyone. It’s pretty bad. I don’t even know myself without this medication. I knew it helped, but I didn’t think it helped to this extreme. I’m hoping the next two days are a little better. Forcing myself to eat and hydrate. Trying to get through this.

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Profile picture for tammy1016 @tammy1016

May I ask what you replaced it with ?

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What is brain zaps?

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Profile picture for looplu79 @looplu79

What is brain zaps?

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Like electrical currents running through your head. Fun.

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I’m down to opening the capsule and taking 1/5th each night to minimize the side effects. I titrate off EXTREMELY slowly! Be prepared for your doctor to look at you like you’re nuts, but whatever it takes and they need to know that some of use are very very sensitive to drugs.

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@pammiedon
have you been having any withdrawal effects on your current taper?
Thanks,
Jake

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