I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you
Yes, you count the beads when you taper slowly. From 37.5 it should be an extremely slow taper, like less than 5%. Don't take it every other day because you'll be in constant ping ponging withdrawals. You count the beads in 3 capsules to get an average of how many beads are in each capsule then divide by the percentage to see how many beads to take out so that the remaining beads are 5% less than your dosage. But right now I would recommend staying at 37.5 until you are absolutely stable before trying to taper at all.
The 37.5 Venlafaxine capsule contains approximately 37 “balls” …37 times .1= 3.7. Subtract this amount from 37 for your next dose.
Liked by Leonard, sandij (Sandi James)
Persevere. Take care of you.
Call the prescribing doctor.
Pharmacists are helpful in explaining any supportive medical like Escitalopram
Liked by Lisa Lucier
I would say at least 3-4 weeks. You want to stay at the reduced dose until you are completely stable. If you have any withdrawal symptoms then stay on it at least another week.
Liked by texasduchess
If you dropped from 150 to 37.5 over some weeks, you are tapering too fast–feeling like cr*p is the big tip off. Ping-ponging on/off from one day to the next is just putting you into withdrawal over and over. The recommendation is to go back to the level where you felt good (that may be 75mg, or even 112.5mg), stabilize there for weeks, or even months before tapering (only 5-10%, or even less) again. Going slooowww is your friend! There's no point rushing the process if you ultimately can't get off Effexor because the withdrawals are too awful.
Is your doctor on board? He can help you taper off Effexor by prescribing a different formulation–changing from extended-release to regular release, or from capsules to tablets (I was on 25mg tablets that could be cut), or specifying a certain brand (@farm_mom found Teva had the most consistent size and number of beads within a capsule–helpful to those counting and throwing out beads to taper). Or your doctor can write a prescription for a compounding pharmacy to make tapered doses for you (the extra cost may well be worth it because you can glide down in incremental amounts, rather than make rather large jagged drops).
Yes, other people opened the capsules and removed beads. @sandij and @doorman just commented on how to do this.
Liked by doorman
I did not find specific info re XR's and regular's half-lives, but did find this: "Effexor XR provides a slower rate of absorption, but the same extent of absorption compared with the immediate-release tablet." The XR version evens out the amount in your system over the course of the day; that may mean the half-life of some of the drug is extended, but that's probably just a few hours.
You will know if you are tapering too fast–withdrawal symptoms are the big tip off. Only you can decide if they're tolerable, or not. If not, the recommendation is to go back to the level where you felt good, stabilize at that dose for weeks (or even months) before tapering again (you may want to taper less than 10% from this point on).
Liked by doorman
Hello. First of all you WILL eventually ween off. Secondly, I believe you’re going too fast still, so give yourself some normalcy and take the 37.5 everyday. When you’re ready, yes. Take out some of those small beads.
I took out 5 beads each time I went down a level. I had zero side effects but it took about 18 months. What’s the hurry?
I did ok but after six months completely clean, I went on Zoloft and seroquel. (Both generic). I was too sick of not being happy and well, truth be told, I was buying and selling too much. My family was suffering and my doctor pointedly told me it is highly likely I am bipolar. And so now I take meds for it. And they’re working 🙂
Good luck and go easy on yourself.
Liked by texasduchess, sandij (Sandi James)
@anne2019
Also, I just want to say THANK YOU to everyone on this post. I was beginning to think I was over-reacting or psycho-somatic. Surely it couldn't be this bad! You have all affirmed that my experience is real! I really want to get off this drug!
Liked by Lisa Lucier, Leonard, sandij (Sandi James)