Tidvak (tisotumab vedotin) therapy for Metastatic Cervical Cancer

Hello!

Thanks for the warm welcome! A little about my journey.. I was first diagnosed back in October 2023. They discovered a mass against my pelvic wall with unknown origin that had similar cells as cervical cancer so that's how my team of doctors proceeded to diagnose & treat my invasive squamous cell carcinoma. I went through chemo & radiation for 5-6 weeks. Afterwards, my PET scans were clear up until the middle of 2024, when I started to feel my pain reoccuring in the same region as before. I had another PET scan and showed a little activity again around my mass. This is my second go at treatment to try and beat this thing. Since I had radiation done in the area prior, the next plan was to try different chemo drugs. I've had approximately 6 rounds of carboplatin and paclitaxel along with 3 rounds of immunotherapy drugs, avastin & keytruda. PET scan results showed the mass is still growing despite chemo treatment so now we are going to try Tivdak. I have had one dose, however, we are on pause until I can get a pain pump, scheduled for next week.. yay! Then I presume, I will continue with the Tivdak treatments. My doctors have given me another option to get rid of my mass but it involves a radical surgery that will be life changing. It will result in amputating my right leg due to the location of the mass. I am a mother of a growing 15 year old boy and caregiver of my soon to be 79 year old mother so I would rather exhaust all other options before having to do surgery. It has been a roller coaster ride for me to say the least both physically and mentally/emotionally. I've recently discovered this group so excited to do more research and read on stories of those with similar journeys. May I ask how you are doing now after your hysterectomy?

Hi … thank you. The treatments are rough. I don’t recover from them well. This week I took a break from them to see if o can recover. I have TIVDAK 11 next week. Then I’m due for a scan. I’m dealing with fatigue and neuropathy mostly. My red blood cell factors are low but not low enough to warrant a blood transfusion. My oncologist wants to keep going with TIVDAK so I’m following his orders!!!!

Would love to hear about your results if you are willing to share! I will be starting treatments here soon. Still feeling anxious but praying we will get the response we want.

I am still on TIVDAK. I will have my 13th treatment next week. I had a scan recently but do not know results yet. TIVDAK is rough after so many treatments. I can’t do much without assistance. I will know more next week.