Tamoxifen 10mg vs 20mg

@colleenyoung, yes, I have a long history of sensitivities to meds. I’m taking a number of other meds for erythromelalgia, migraines, and other conditions. All of my specialists are looking out for interactions. No specific known interactions w tamoxifen, but my oncologist and neurologist had some concerns/expectations upfront on what side effects could be worse for me, just given what the typical side effects are and what my conditions are, coupled w what meds I take. Not to mention the ones I have taken over the years that have given me problems.
I’m ready to see what alternative might be better- messaged my dr through the portal this weekend. All of the wonderful ladies on her have given me hope that it’s worth some trial and error for something else.

Welcome, @kellyc14. It sounds like you have a history of sensitivity to medications. The side effects you're experiencing with Tamoxifen sound rough. Fingers crossed that the side effect ease up over time.

Do you take medication for your other conditions like erythromelalgia and migraines? Have you consulted with a pharmacist about drug interactions and symptom management?

Hi all. New here. I started tamoxifen a month ago. 10mg. Half dose bc of long history of difficulties w meds and other conditions (migraines, erythromelalgia). I hate the side effects so far. They trigger my erythromelalgia flares and I’m walking around in a brain fog. Not sure how long to give it before I give up. 48 y/o.

Thanks for your response, I really appreciate everyone's information. I referred the question to my onocologist, currently is out of the office - so maybe mid July for that response. But any of additional info would be great! Best to you, I have been on a AI for @ a year and a half and doing well. Concentrating hard on switching to a plant based diet and of course exercise!

Yes you did! Thanks. I just sent you a message.

@sparklegram - Thank you, Sparklegram and I hope you can find some relief or perhaps try something else. By the way, I believe I told you once before, I love your name!

Thank you for your response, Buckimom. I hope you have a full recovery from this drug!

@sparklegram - I thought I could go the distance, at least 5 years. The first year was a breeze; the 2nd was as destructive as being hit by a Mack truck. My hands & feet are crippled (now I'm going to be tested for Rheumatoid & Lupis. From the Arimidex? Don't know yet. Yes, my oncologist told me that my ductal carcinoma insitu was caught very early; all my mammograms have been clean; bloodwork is good oncologically and he feels I will be fine with no more Arimidex. My quality of life has slipped to practically zero. Luckily for me, my God given gift is the ability to entertain myself, lol.

@buckimom,- I SO want to get away from Arimidex as far away as possible, but I'm worried about the side effects of the other meds. what was your OncotypeDX score, Buckimom? Did your oncologist say it was OK to go off all of the drugs?

@100154 - i’ve has experience with Arimidex only. I was taken off of it last month, after 2 years, due to devastation to my joints and muscles. I’m not a candidate for Tamoxifin due to cardiac issues. I will not be trying any other “zole” medication & will be watched carefully.

A gal in this group posted info from her oncologist regarding percentages. I saved it and wii repost if permissible. Let me know.

All the best to you ❤️