Symptoms from radiation/chemo for endometrial cancer? What helps?

Posted by smmc2025 @smmc2025, Jan 20, 2025

Ladies, if you could share your radiation & chemo symptoms and what you did to alleviate them? I’m getting ready for approx five weeks of these treatments for recurring endometrial cancer in upper right vaginal cuff. I’m nearly 5 years from endometrial cancer & complete hysterectomy. Recurrence discovered at physical exam in Sept 2024, followed by CT, Pet scan and biopsy. Pathology showed recurrence of same adenocarcinoma Figo 1, Grade 1 in vaginal cuff. Thank you for your support.

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Thank you all for sharing your journey out here; it is so helpful.

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Profile picture for riverland889 @riverland889

I am in similar situation to smmc2025. I was 3 years post full hysterectomy (did hyster because of bleeding, a tumor was found in the endometrium); Recurrence discovered 3 years later via pelvic exam. CT, Pet scan and biopsy followed, Pathology showed recurrence of same adenocarcinoma Figo 1, Grade 1 in my left vaginal cuff. I then did 5 weeks external radiation with once a week low dose chemo (cisplatin); the 5 sessions of brachytherapy. I didn't think there could possible be anything left after that. But a bit still showed on my scans. So now, because I can't do anymore radiation in that area, I have done 5 immunotherapy infusions (30 min a session), 3 weeks apart. Now switching to 6 weeks. Doing fine, recent scan was clear. No side effects yet. Keeping fingers crossed. Hope this is helpful in some way.

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Riverland889-so helpful; thank you. I’ve been hesitant about the immunotherapy; can you share which drug they used for immunotherapy? They’re mentioning Jemperli? To me. Wishing you complete healing and recovery.

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Profile picture for smmc2025 @smmc2025

Riverland889-so helpful; thank you. I’ve been hesitant about the immunotherapy; can you share which drug they used for immunotherapy? They’re mentioning Jemperli? To me. Wishing you complete healing and recovery.

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Jemperli. My oncologist explained that this particular drug is very receptive to my type of cancer, which sounds like it could be for yours also (but I'm NOT a doctor LOL). I don't want to jinx it, but so far I have no side effects and have received 5 infusions. Wishing you the best of luck in getting the proper treatment. please feel free to communicate with me.

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Profile picture for riverland889 @riverland889

Jemperli. My oncologist explained that this particular drug is very receptive to my type of cancer, which sounds like it could be for yours also (but I'm NOT a doctor LOL). I don't want to jinx it, but so far I have no side effects and have received 5 infusions. Wishing you the best of luck in getting the proper treatment. please feel free to communicate with me.

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Riverland, Thank you so much; I’m going to try the immunotherapy next infusion appt and it is jemperli that they are recommending. So thankful for you that you are responding well. Blessings, Smmc

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Please let me know how you do. Mine is a 30 min. infusion, goes quickly.

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Profile picture for riverland889 @riverland889

I am in similar situation to smmc2025. I was 3 years post full hysterectomy (did hyster because of bleeding, a tumor was found in the endometrium); Recurrence discovered 3 years later via pelvic exam. CT, Pet scan and biopsy followed, Pathology showed recurrence of same adenocarcinoma Figo 1, Grade 1 in my left vaginal cuff. I then did 5 weeks external radiation with once a week low dose chemo (cisplatin); the 5 sessions of brachytherapy. I didn't think there could possible be anything left after that. But a bit still showed on my scans. So now, because I can't do anymore radiation in that area, I have done 5 immunotherapy infusions (30 min a session), 3 weeks apart. Now switching to 6 weeks. Doing fine, recent scan was clear. No side effects yet. Keeping fingers crossed. Hope this is helpful in some way.

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@riverland889 what immunotherapy did you have?

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Profile picture for belle4 @belle4

@riverland889 what immunotherapy did you have?

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@belle4
I’m receiving Jemperli now every 6 weeks, 1/2hour infusion. When I first started it was every 3 weeks. I have been on it for over a year and will likely stay on it for another two years if all keeps going well.

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Profile picture for riverland889 @riverland889

@belle4
I’m receiving Jemperli now every 6 weeks, 1/2hour infusion. When I first started it was every 3 weeks. I have been on it for over a year and will likely stay on it for another two years if all keeps going well.

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@riverland889 thank you!! I am on Jemperli and have been during my 6 chemo treatments. Now going to just Jemperli every six weeks but 1000 instead of 500mg. Are you experiencing any side effects? I am hoping that my side effects were mainly from the chemo. I am only 2 weeks and 4 days out from my final chemo. Any insight you have would be appreciated.
All the best to you as we soldier on.

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My oncologist said that the future may be just the Jemperli or other immunotherapy, and no chemo. I haven’t had any side effects but other people report things like rashes, or headaches. I have been lucky. It’s been about 15 months. I am on 1,000 mg
Hope that helps

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