Switch from Folfirinox to Gem/Abrax due to non response
Hello, my dad has had 8 rounds of Folfirinox, and initially was told that he was a candidate for surgery by both our local healthcare system and also a larger NCI center we visited. At Mayo, he was told that he is stage 4 and not a surgical candidate due to the lymph nodes involved along his aorta. All of his scans – PET and CT have been stable throughout – from beginning to the 4month point we are at now. Suggestions to us was that he switch types of chemo or look at trials. Hoping that the lymph nodes shrink to make surgery possible. Potentially radiation. He's had no trouble tolerating the Folfirinox. Initially we'd be told all along the way that there were no major arteries or veins involved, but Mayo said that they are. Who has dealt with a similar situation? Did Gem/abrax help shrink your tumors/nodes when Folfirinox didn't? Thought we were doing good by being on what they say is the "stronger" drug.