Surgery or Radiation if large cribriform found in biopsy?

Posted by bhDC @bhdc, Jun 25 9:50am

Does anyone know the latest on what research (or generally accepted practice) says about surgery or radiation being the most effective way to address large cribriform?

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Fascinating discussion. Thanks to all who participated. Cribiform is being acknowledged as an independent risk factor but there sure doesn't seem to be consensus on what that means. My read to date is that it is a risk not fully captured by the Gleason scale so those of us that have this variant must be vigilant in asking these questions and pressing on whether standard treatment protocols are sufficient. It also occurred to me that I don't know if I have/ had large or small cribiform and I am not sure I need to know since I originally had surgery and now am on ADT after salvage radiation. Best wishes to all. Dave

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Profile picture for wheel1 @wheel1

Look into single port Retzius sparing surgery. Clearly at 74 you are pushing the envelope for surgery, but if you are in good health, check out the continence success with Retzius sparing surgery.

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@wheel1 Thanks - Dr. Sprenkle, my doc was one the first to use it at Yale. He showed me just why on my MRI my anatomy may not be amenable to the surgery. When I met him, I told him if it comes to that - "take it out". I appreciate an honest practitioner. Right now, both Yale and Hartford Health Care (Joseph Wagner, who's done the most RP's in the state of CT) advised that I'm intermediate, favorable risk. I'm still concerned, and that's why I'm here discussing this.

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