Surgery or Radiation if large cribriform found in biopsy?

Posted by bhDC @bhdc, Jun 25 9:50am

Does anyone know the latest on what research (or generally accepted practice) says about surgery or radiation being the most effective way to address large cribriform?

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Fascinating discussion. Thanks to all who participated. Cribiform is being acknowledged as an independent risk factor but there sure doesn't seem to be consensus on what that means. My read to date is that it is a risk not fully captured by the Gleason scale so those of us that have this variant must be vigilant in asking these questions and pressing on whether standard treatment protocols are sufficient. It also occurred to me that I don't know if I have/ had large or small cribiform and I am not sure I need to know since I originally had surgery and now am on ADT after salvage radiation. Best wishes to all. Dave

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Profile picture for wheel1 @wheel1

Look into single port Retzius sparing surgery. Clearly at 74 you are pushing the envelope for surgery, but if you are in good health, check out the continence success with Retzius sparing surgery.

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@wheel1 Thanks - Dr. Sprenkle, my doc was one the first to use it at Yale. He showed me just why on my MRI my anatomy may not be amenable to the surgery. When I met him, I told him if it comes to that - "take it out". I appreciate an honest practitioner. Right now, both Yale and Hartford Health Care (Joseph Wagner, who's done the most RP's in the state of CT) advised that I'm intermediate, favorable risk. I'm still concerned, and that's why I'm here discussing this.

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Profile picture for dhasper @dhasper

Fascinating discussion. Thanks to all who participated. Cribiform is being acknowledged as an independent risk factor but there sure doesn't seem to be consensus on what that means. My read to date is that it is a risk not fully captured by the Gleason scale so those of us that have this variant must be vigilant in asking these questions and pressing on whether standard treatment protocols are sufficient. It also occurred to me that I don't know if I have/ had large or small cribiform and I am not sure I need to know since I originally had surgery and now am on ADT after salvage radiation. Best wishes to all. Dave

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@dhasper
Are you done with RT πŸ˜ƒ ??? If yes CONGRATS ! I hope that you did not have any special irritation of the bladder or rectum πŸ€ and are now just counting days till the end of ADT : ))) ! You got only 4 mos of it - right ? You must be really relieved and happy to now embrace all summer fun that is ahead of you : ))) !
Don't forget all of us here ; ) !!! lol

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Profile picture for dacaesar @dacaesar

@wheel1 Thanks - Dr. Sprenkle, my doc was one the first to use it at Yale. He showed me just why on my MRI my anatomy may not be amenable to the surgery. When I met him, I told him if it comes to that - "take it out". I appreciate an honest practitioner. Right now, both Yale and Hartford Health Care (Joseph Wagner, who's done the most RP's in the state of CT) advised that I'm intermediate, favorable risk. I'm still concerned, and that's why I'm here discussing this.

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@dacaesar
You have really competent and caring doctors, there is no doubt about it πŸ‘πŸ˜ƒ ! You are in good hands and it is a blessing : ))).

Wishing you great results with whatever path you choose πŸ€ : ))) !

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Profile picture for surftohealth88 @surftohealth88

@dacaesar
You have really competent and caring doctors, there is no doubt about it πŸ‘πŸ˜ƒ ! You are in good hands and it is a blessing : ))).

Wishing you great results with whatever path you choose πŸ€ : ))) !

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@surftohealth88 Definitely one of the luckier people in the country with great insurance where I can choose to go wherever to get the best care. And being in RI, near centers of excellence doesn't hurt either!

Thanks!

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