Completed 5 years of anastrozole. Withdrawal symptoms? Side effects?

@smspaz59 Yes! Just about the same timeframe & same symptoms. Trying to get my energy back. Hopefully others who have had same experience will post suggestions.

I have been reading up on all the comments. Most are about the effects when they are on it but only a few regarding when they go off. I am grateful and blessed to say I did not have much problems when I was put on it back in 2020. In the midst now that I read reviews, I think my plantar facitis started then. I just stopped in mid March this year after 5 years on Anastrozole. I noticed my right leg gets a bit tired after a bout of walking....but most of all I notice (rather my friends did) that I have lost weight. This is a major worry for me as I equate weight loss to cancer. But I just had my annual check up. My mamongram came back clear. My blood test cancer marker came back good. Cholestrol is good. Sugar level is good, no diabetes but slightly anemic. I am a small eater all my life but why am I losing weight? Oh I did not gain weight when I was Anastrozole. Anyone has this weight loss problem????Appreciate an input.

So did anyone else get off anastrozole, and how long were you on it before you stopped? And did you have surgery at some point along the way? Thank you!

I had 3 positive lymph nodes too and prescribed Verzenio. Just wondering if you ever took it and what your experience was?

I took myself off the anastrozole 2 weeks ago and still have the severe stiffness in my fingers and shoulders. I see my oncologist in 3 weeks to discuss these problems.

For me it took about 6 months to feel like myself again. Those drugs really beat the sh⭐️t out of me . The fatigue was the least of my problems. My bones were in constant pain .

Hi, would you be able to give me the website for the message board in the UK?
Thank you!

I appreciate your comments. I have felt fatigue on anastrazole and still 4 weeks after stopping (finished 5 years). Each year fatigue got a little worse and I too just do what I need to do. I am still able to strength training 3x a week and push myself but rest when I feel.like doing nothing much. I have been assured that the fatigue will get much better but to set realistic expectations because it can take months for your body to readjust. Patience is hard but I trust my oncologist!

I finished 5 years on Aug 24. No withdrawal but it is taking time to feel like I am not on it anymore. A lot of fatigue but I had terrible sleep for 5 years. So I think this is going to take time.

I wrote that in 2024. I had no heart issues before exemestane. Long story short.. in 2021 or 2022 i went to the ER. I was told i had either had passed a blood clot or had an arterial spasm. Cardiologist didnt know. He asked me if exemestane was a prothrombotic. I didnt know.
I took myself off exemestane because i didnt know what caused the heart episode neither did the docs.

Since April2025, im now back on exemestane.
However, since my heart episode in 2021/22, i immediately got off coffee and caffine.
Ive not had any heart incidents to attribute to exemestane but now, I do have afib randomly, but that started PRIOR to me going back on exemestane.