Stage 4 metastatic prostate cancer

Posted by majed @majed, 16 hours ago

Hi all
My husband was diagnised with stage 4 metastatic prostate cancer, it has spread to bones and nearby lymph nodes, he is 51 and with other health issues
Whatbis his prognosis please

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No one can really tell you how long he has. He needs to get treatment, and it could stop the cancer in its tracks. His Gleason score tells you a lot about how aggressive the cancer is, Find that out from the doctor.

You need to find a good doctor for Either a second opinion or a primary doctor, a Genito Urinary Oncologist, or a center of excellence like Mayo would give you the best chance of your husband having a remission.

Normally he would be considered for triple therapy. ADT plus abiraterone or a lutamide plus Chemo. Health is a major factor however. That’s why it’s so important to see a doctor. They may only want to do some of those things.

They also may want to do radiation on the prostate, the bone metz and the Lymph nodes. Depends on how many spots there are.

They could use Pluvicto early to try and kill everything. There are so many choices.

You could request a Decipher test to see how likely metastasis is to return soon.

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Stage 4 to my spine in 2021 at age 56. I'm still here, still going strong, and still in full medically-induced remission.

Everyone's experience will be different, but especially if the stage 4 cancer is "oligometastatic" (just a few metastases) and "castrate-sensitive" (responds to hormone therapy), the prognosis could potentially be good, especially if he's getting modern treatments like radiation to his prostate and metastases, and one of the second generation ARSIs (the -lutamides) as part of his hormone therapy. More here:
https://www.scientificamerican.com/article/treating-prostate-cancer-at-any-stage/

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@northoftheborder

Stage 4 to my spine in 2021 at age 56. I'm still here, still going strong, and still in full medically-induced remission.

Everyone's experience will be different, but especially if the stage 4 cancer is "oligometastatic" (just a few metastases) and "castrate-sensitive" (responds to hormone therapy), the prognosis could potentially be good, especially if he's getting modern treatments like radiation to his prostate and metastases, and one of the second generation ARSIs (the -lutamides) as part of his hormone therapy. More here:
https://www.scientificamerican.com/article/treating-prostate-cancer-at-any-stage/

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What was your tratmwnt plan please

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@jeffmarc

No one can really tell you how long he has. He needs to get treatment, and it could stop the cancer in its tracks. His Gleason score tells you a lot about how aggressive the cancer is, Find that out from the doctor.

You need to find a good doctor for Either a second opinion or a primary doctor, a Genito Urinary Oncologist, or a center of excellence like Mayo would give you the best chance of your husband having a remission.

Normally he would be considered for triple therapy. ADT plus abiraterone or a lutamide plus Chemo. Health is a major factor however. That’s why it’s so important to see a doctor. They may only want to do some of those things.

They also may want to do radiation on the prostate, the bone metz and the Lymph nodes. Depends on how many spots there are.

They could use Pluvicto early to try and kill everything. There are so many choices.

You could request a Decipher test to see how likely metastasis is to return soon.

Jump to this post

Thanks

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@majed

What was your tratmwnt plan please

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My treatment course:

1. Emergency debulking surgery for the spinal lesion (which had compressed my spinal cord and paralyzed my legs).

2. 20 gy of post-surgical SBRT radiation to my spine spread over 5 sessions.

3. ADT (initially Firmagon, now Ogovyx) and Erleada/Apalutamide, ongoing, which rapidly reduced my PSA to undetectable.

4. 60 gy of SBRT radiation to my prostate itself, spread over 20 sessions.

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@northoftheborder

My treatment course:

1. Emergency debulking surgery for the spinal lesion (which had compressed my spinal cord and paralyzed my legs).

2. 20 gy of post-surgical SBRT radiation to my spine spread over 5 sessions.

3. ADT (initially Firmagon, now Ogovyx) and Erleada/Apalutamide, ongoing, which rapidly reduced my PSA to undetectable.

4. 60 gy of SBRT radiation to my prostate itself, spread over 20 sessions.

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God bless yoy with health
Hope you are able to walk now after the radiation

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@northoftheborder

Stage 4 to my spine in 2021 at age 56. I'm still here, still going strong, and still in full medically-induced remission.

Everyone's experience will be different, but especially if the stage 4 cancer is "oligometastatic" (just a few metastases) and "castrate-sensitive" (responds to hormone therapy), the prognosis could potentially be good, especially if he's getting modern treatments like radiation to his prostate and metastases, and one of the second generation ARSIs (the -lutamides) as part of his hormone therapy. More here:
https://www.scientificamerican.com/article/treating-prostate-cancer-at-any-stage/

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Sad…you went thru the meat grinder.

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@majed

God bless yoy with health
Hope you are able to walk now after the radiation

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Yes, it took a couple of years, but I got about 80% of my mobility back. Thank you.

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@ecurb

Sad…you went thru the meat grinder.

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The silver lining is that I never had to go through the agonising decision-making most of the rest of you went through, worrying about overtreatment, undertreatment, active surveillance, quality of life, etc etc.

I was suddenly flat on my back in a critical-care hospital bed with a bed pan. I *knew* it was serious, and I wasn't overly worried about extra side-effects from aggressive treatment. I just wanted to fight my way out of there.

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