Stage 4 Malignant Melanoma internal

Hi I was diagnosed stage 4 metastatic melanoma on my liver September 2015. No primary cancer point. The tumor was 15cm X 8 cm.... Inoperable. Fortunately the immunotherapy is working . I asked my oncologist is I would ever get to the NED status and she was I don't think so. I'm stable , no spreading , and the tumor has shrunk a great deal.
Is there anyone that is in a similar situation?

Hi I was diagnosed stage 4 metastatic melanoma on my liver September 2015. No primary cancer point. The tumor was 15cm X 8 cm.... Inoperable. Fortunately the immunotherapy is working . I asked my oncologist is I would ever get to the NED status and she was I don't think so. I'm stable , no spreading , and the tumor has shrunk a great deal.
Is there anyone that is in a similar situation?

Hi I was diagnosed stage 4 metastatic melanoma on my liver September 2015. No primary cancer point. The tumor was 15cm X 8 cm.... Inoperable. Fortunately the immunotherapy is working . I asked my oncologist is I would ever get to the NED status and she was I don't think so. I'm stable , no spreading , and the tumor has shrunk a great deal.
Is there anyone that is in a similar situation?

Hi Pam, welcome to Connect. I'd like to introduce you to a few fellow members who have experience with melanoma. First, please meet @lynnkay1956 who is also living with stage 4 melanoma, as well as @lindabf and @psfrazier who are caregivers to family members who have metastatic melanoma. @texas7777 and @cynaburst have had early stage melanoma.

Pam, are currently not taking any treatment?
We look forward to getting to know more about you.

Good news Meg4434 is that you are stable. Sounds like the combo of Yervoy/Opdivo did its work and reduced the tumor. It is my understanding that sometimes those drugs take time to work, so patience is impt. I pray your tumor continues to reduce.
I had been treated with Yervoy first, followed by Opdivo for my leg melanomas. I was lucky, after 2 infusions with Opdivo, all the melanomas disappeared - a true miracle. I could only withstand 6 infusions as my body went into total inflammation and Dr decided to stop the treatment. I still have some side effects (arthritis, joint pain, eye irritation, low sodium/hemoglobin counts) but all manageable. Prednisone has been my friend of late! But I am cancer free almost 2 yrs now, and very grateful.
Wish I could be of more help, but my experience has been limited, as the melanomas have not travelled beyond my leg, as of yet. I stay positive, but I do understand the melanomas are never curable, we just have to stay one step ahead.

Am having a y90 on Tues. I am so scared. This is all new to me. Please respond.

Do not be afraid Y90 is ok I got it feels I felt just little burning by my liver stomach since my cancer is liver mild pain because of the procedure my was by my leg going to my liver after that didn’t feel nauseous or chills just tiredness but again every body is diferente just be positive strong we got this F$&@ Cancer praying for you 🙏🏻🙏🏻

They have basically moved away ( at least for now) conventional chemotherapy and are now using targeted drugs like the B-raf and MEK inhibitors and Immunotherapy drugs like Ipilimumab ( yervoy) Nivolumab (opdivo) and Keytruda...they basically take off the brakes and kick up the immune system ( the opposite of chemo which kills fast growing cells, good and bad ones) . IL-2, interferon were the oldest drugs approved by the FDA for melanoma. Leukine is different in that it is a man-made protein that stimulates the growth of white blood cells in your body. Interferon is also a group of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses-they are found in the body and also man made...they don't do much for melanoma but do have some nasty side effects. Ipilimumab ( yervoy) Nivolumab (opdivo) and Keytruda are considered the gold star of melanoma treatments now. They are also doing TIL therapy but it is more complicated and does not have as high of response rate as Nivolumab or Keytruda.

After having a third Melanoma 8 years ago the first was negative and most recently 2 were positive 1 removed 5 years ago and 1 more 6 months ago, this last time 2 Lymph Nodes that were negative we have decided that the best move forward would be to start Keytruda. I have just had my first Keytruda infusion and feel great. No obvious side effects at this point, no loss of energy or pain!